Protein: CDC25
Cell division control protein 25

Gene: CDC25
Organism: Saccharomyces cerevisiae S288C
Interactions: 97
UniProt ID: P04821

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

350781

RAS2
Ras-like protein 2

9

20

Small-scale

0.975

High

350755

RAS1
Ras-like protein 1

4

20

Small-scale

0.893

High

389665

CDC25
Cell division control protein 25

1

3

Small-scale

0.713

High

389725

MDS3
Negative regulator of sporulation MDS3

4

1

High-throughput

0.700

High

389666

KAPA
cAMP-dependent protein kinase type 1

3

5

Small-scale

0.686

High

389693

HRR25
Casein kinase I homolog HRR25

3

2

Small-scale

0.667

High

365522

HSP82
ATP-dependent molecular chaperone HSP82

3

1

Small-scale

0.648

High

389708

SSZ1
Ribosome-associated complex subunit SSZ1

2

3

High-throughput

0.601

High

389685

PP11
Serine/threonine-protein phosphatase PP1-1

2

0

High-throughput

0.595

High

389738

DIG2
Down-regulator of invasive growth 2

2

0

High-throughput

0.588

High

389701

BRR2
Pre-mRNA-splicing helicase BRR2

2

0

Small-scale

0.587

High

389689

CG23
G2/mitotic-specific cyclin-3

2

0

Small-scale

0.585

High

389680

FUS3
Mitogen-activated protein kinase FUS3

1

3

Small-scale

0.578

High

389714

SA185
SIT4-associating protein SAP185

2

0

High-throughput

0.576

High

389669

CYAA
Adenylate cyclase

1

1

Small-scale

0.561

High

389678

KSS1
Mitogen-activated protein kinase KSS1

1

3

Small-scale

0.561

High

389676

KIN1
Serine/threonine protein kinase KIN1

1

1

High-throughput

0.541

High

389696

VPS10
Vacuolar protein sorting/targeting protein VPS10

1

1

High-throughput

0.541

High

389697

BTAF1
TATA-binding protein-associated factor MOT1

1

1

High-throughput

0.541

High

389700

PMD1
Negative regulator of sporulation PMD1

1

1

High-throughput

0.541

High

389712

VTH1
VPS10 homolog 1

1

1

High-throughput

0.541

High

389753

EAF3
Chromatin modification-related protein EAF3

1

2

High-throughput

0.541

High

389667

KAPB
cAMP-dependent protein kinase type 2

1

4

High-throughput

0.536

High

389686

MCK1
Protein kinase MCK1

1

3

High-throughput

0.536

High

389694

BMH1
Protein BMH1

1

4

High-throughput

0.536

High

389707

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

3

High-throughput

0.536

High

389674

AK
Aspartokinase

1

0

High-throughput

0.518

High

389677

STE12
Protein STE12

1

0

High-throughput

0.518

High

389687

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.518

High

389690

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.518

High

389695

ACBP
Acyl-CoA-binding protein

1

0

High-throughput

0.518

High

389705

SHE3
SWI5-dependent HO expression protein 3

1

0

High-throughput

0.518

High

389716

NMD5
Nonsense-mediated mRNA decay protein 5

1

0

High-throughput

0.518

High

389722

BUL1
Ubiquitin ligase-binding protein BUL1

1

0

High-throughput

0.518

High

389731

PDR16
Phosphatidylinositol transfer protein PDR16

1

0

High-throughput

0.518

High

389732

DMA2
E3 ubiquitin-protein ligase DMA2

1

0

High-throughput

0.518

High

389735

ATG21
Autophagy-related protein 21

1

0

High-throughput

0.518

High

389736

DIG1
Down-regulator of invasive growth 1

1

0

High-throughput

0.518

High

389737

MET31
Transcriptional regulator MET31

1

0

High-throughput

0.518

High

389743

RPN7
26S proteasome regulatory subunit RPN7

1

0

High-throughput

0.518

High

389749

PSR2
Probable phosphatase PSR2

1

0

High-throughput

0.518

High

389752

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.518

High

389719

IML1
Vacuolar membrane-associated protein IML1

1

0

High-throughput

0.517

High

389671

HSP73
Heat shock protein SSA3

1

4

Small-scale

0.515

High

389672

HSP71
Heat shock protein SSA1

1

4

Small-scale

0.515

High

389673

HSP72
Heat shock protein SSA2

1

4

Small-scale

0.515

High

389720

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

0

High-throughput

0.513

High

389668

PBS2
MAP kinase kinase PBS2

1

4

High-throughput

0.501

High

389675

INO1
Inositol-3-phosphate synthase

1

1

High-throughput

0.501

High

389691

NFS1
Cysteine desulfurase, mitochondrial

1

1

High-throughput

0.501

High

389698

IME2
Meiosis induction protein kinase IME2/SME1

1

2

High-throughput

0.501

High

389715

KEG1
Beta-1,6-glucan synthesis-associated protein KEG1

1

1

High-throughput

0.501

High

389723

GCSP
Glycine dehydrogenase

1

1

High-throughput

0.501

High

389724

ALG10
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

1

High-throughput

0.501

High

389726

LSG1
Large subunit GTPase 1

1

1

High-throughput

0.501

High

389745

BSP1
Protein BSP1

1

1

High-throughput

0.501

High

389755

YI31B
Transposon Ty3-I Gag-Pol polyprotein

1

1

High-throughput

0.501

High

389683

IRA1
Inhibitory regulator protein IRA1

1

2

High-throughput

0.494

High

389713

BNR1
BNI1-related protein 1

1

1

High-throughput

0.494

High

389729

RT19
Small ribosomal subunit protein uS19m

1

1

High-throughput

0.494

High

389027

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.480

High

389681

SPO7
Sporulation-specific protein SPO7

1

0

High-throughput

0.480

High

389688

DPB2
DNA polymerase epsilon subunit B

1

0

High-throughput

0.480

High

389702

PRX1
Peroxiredoxin PRX1, mitochondrial

1

0

High-throughput

0.480

High

389703

IMB2
Importin subunit beta-2

1

0

Small-scale

0.480

High

389709

LCF3
Long-chain-fatty-acid--CoA ligase 3

1

0

High-throughput

0.480

High

389727

FHN1
Non-classical export protein 2 homolog 1

1

0

High-throughput

0.480

High

389740

SSY1
SPS-sensor component SSY1

1

0

High-throughput

0.480

High

389741

TPP1
Polynucleotide 3'-phosphatase

1

0

High-throughput

0.480

High

389747

YET3
Endoplasmic reticulum transmembrane protein 3

1

0

High-throughput

0.480

High

389684

CG12
G1/S-specific cyclin CLN2

1

1

Small-scale

0.479

High

57900

YM084
Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.460

High

389679

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

389692

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

389699

TOR2
Serine/threonine-protein kinase TOR2

1

0

High-throughput

0.458

High

389717

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.458

High

389721

ASK10
Activator of SKN7 protein 10

1

0

High-throughput

0.458

High

389734

MUK1
Protein MUK1

1

0

High-throughput

0.458

High

389742

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

389744

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

389748

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

389751

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

389718

YJ00
UPF0508 protein YJR030C

1

1

High-throughput

0.457

High

389730

YN93
Uncharacterized hydrolase YNR064C

1

1

High-throughput

0.457

High

389746

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

1

High-throughput

0.445

High

389670

PRTB
Cerevisin

1

2

High-throughput

0.437

High

389710

NPR2
Nitrogen permease regulator 2

1

1

High-throughput

0.437

High

389711

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

389739

NSE5
Non-structural maintenance of chromosome element 5

1

0

High-throughput

0.426

High

389750

CWC2
Pre-mRNA-splicing factor CWC2

1

0

High-throughput

0.426

High

389706

YB75
Uncharacterized protein YBR225W

4

0

High-throughput

0.356

High

389704

YBQ3
Uncharacterized protein YBR053C

1

0

High-throughput

0.282

High

389733

SPR6
Sporulation-specific protein

1

0

High-throughput

0.282

High

389682

COQ1
Hexaprenyl pyrophosphate synthase, mitochondrial

1

0

High-throughput

0.261

Low

389728

COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

1

0

High-throughput

0.261

Low

389754

IRC11
Putative increased recombination centers protein 11

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024