Protein: SIT1
Signaling threshold-regulating transmembrane adapter 1 (SHP2-interacting transmembrane adapter protein) (Suppression-inducing transmembrane adapter 1) (gp30/40)

Gene: SIT1
Organism: Homo sapiens
Interactions: 16
UniProt ID: Q9Y3P8

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0019900 - kinase binding
GO:0042169 - SH2 domain binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

295715

UPK1B
Uroplakin-1b

2

1

High-throughput

0.606

High

225459

ITM2A
Integral membrane protein 2A

2

0

High-throughput

0.580

High

934300

BI1
Bax inhibitor 1

2

0

High-throughput

0.580

High

1092842

MALL
MAL-like protein

2

0

High-throughput

0.580

High

1288423

TSN33
Tetraspanin-33

2

0

High-throughput

0.580

High

440257

LCK
Tyrosine-protein kinase Lck

1

1

Small-scale

0.479

High

440801

FYN
Tyrosine-protein kinase Fyn

1

1

Small-scale

0.479

High

849088

ZAP70
Tyrosine-protein kinase ZAP-70

1

4

Small-scale

0.479

High

849275

KSYK
Tyrosine-protein kinase SYK

1

4

Small-scale

0.479

High

49831

CLRN2
Clarin-2

2

0

High-throughput

0.316

High

335584

BMP10
Bone morphogenetic protein 10

2

0

High-throughput

0.316

High

688426

PPLA
Phospholamban

2

0

High-throughput

0.316

High

1410688

APOL2
Apolipoprotein L2

2

0

High-throughput

0.316

High

1450224

TM140
Transmembrane protein 140

2

0

High-throughput

0.316

High

1053775

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

0

Small-scale

0.289

High

941617

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025