Protein: ITM2A
Integral membrane protein 2A (Protein E25)

Gene: ITM2A
Organism: Homo sapiens
Interactions: 22
UniProt ID: O43736

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0002317 - plasma cell differentiation
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0042985 - negative regulation of amyloid precursor protein biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

225441

DOA
HLA class II histocompatibility antigen, DO alpha chain

2

8

High-throughput

0.628

High

225443

ATP7B
Copper-transporting ATPase 2

2

10

High-throughput

0.628

High

225445

AT12A
Potassium-transporting ATPase alpha chain 2

2

7

High-throughput

0.628

High

225446

ATP7A
Copper-transporting ATPase 1

2

8

High-throughput

0.628

High

225456

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

2

1

High-throughput

0.628

High

225439

CLD7
Claudin-7

2

2

High-throughput

0.606

High

225442

FCGR1
High affinity immunoglobulin gamma Fc receptor I

2

4

High-throughput

0.606

High

225455

TMED9
Transmembrane emp24 domain-containing protein 9

2

2

High-throughput

0.606

High

225459

SIT1
Signaling threshold-regulating transmembrane adapter 1

2

0

High-throughput

0.580

High

223572

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

2

1

High-throughput

0.574

High

225453

RSPRY
RING finger and SPRY domain-containing protein 1

2

1

High-throughput

0.574

High

225458

DJC16
DnaJ homolog subfamily C member 16

2

6

High-throughput

0.574

High

225451

FNDC9
Fibronectin type III domain-containing protein 9

2

1

High-throughput

0.553

High

225447

DDR1
Epithelial discoidin domain-containing receptor 1

1

3

High-throughput

0.536

High

225452

S67A1
Solute carrier family 67 member A1

1

7

High-throughput

0.536

High

225440

A4
Amyloid-beta precursor protein

1

6

Small-scale

0.515

High

225449

T179B
Transmembrane protein 179B

1

0

High-throughput

0.493

High

225448

TRI14
Tripartite motif-containing protein 14

1

2

High-throughput

0.439

High

225454

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.437

High

225450

KLH36
Kelch-like protein 36

2

0

High-throughput

0.328

High

225444

MEOX2
Homeobox protein MOX-2

1

0

High-throughput

0.299

High

225457

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025