Protein: COLI
Pro-opiomelanocortin (POMC) (Corticotropin-lipotropin) [Cleaved into: NPP; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanocyte-stimulating hormone alpha (Alpha-MSH) (Melanotropin alpha); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanocyte-stimulating hormone beta (Beta-MSH) (Melanotropin beta); Beta-endorphin; Met-enkephalin]

Gene: COLI, POMC
Organism: Homo sapiens
Interactions: 31
UniProt ID: P01189

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0005102 - signaling receptor binding
GO:0005179 - hormone activity
GO:0005184 - neuropeptide hormone activity
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

351591

MC4R
Melanocortin receptor 4

2

3

Small-scale

0.778

High

351592

MC5R
Melanocortin receptor 5

1

3

Small-scale

0.647

High

351593

MC3R
Melanocortin receptor 3

1

3

Small-scale

0.647

High

351597

MSHR
Melanocyte-stimulating hormone receptor

1

3

Small-scale

0.647

High

351599

E2F4
Transcription factor E2F4

2

1

High-throughput

0.628

High

351595

ERR3
Estrogen-related receptor gamma

2

0

High-throughput

0.580

High

351602

C102B
Coiled-coil domain-containing protein 102B

2

0

High-throughput

0.580

High

351603

BHA09
Class A basic helix-loop-helix protein 9

2

0

High-throughput

0.580

High

351604

HDDC2
5'-deoxynucleotidase HDDC2

2

0

High-throughput

0.580

High

351605

GLCTK
Glycerate kinase

2

0

High-throughput

0.580

High

351613

AIRIM
AFG2-interacting ribosome maturation factor

2

0

High-throughput

0.580

High

351614

ABI2
Abl interactor 2

2

0

High-throughput

0.580

High

351616

OAZ3
Ornithine decarboxylase antizyme 3

2

0

High-throughput

0.580

High

351607

PRS33
Serine protease 33

1

0

High-throughput

0.513

High

351588

VTNC
Vitronectin

1

0

Small-scale

0.480

High

351589

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

351596

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

0

Small-scale

0.426

High

50292

TSN11
Tetraspanin-11

2

0

High-throughput

0.328

High

351590

DCAM
S-adenosylmethionine decarboxylase proenzyme

2

0

High-throughput

0.328

High

351601

UBR4
E3 ubiquitin-protein ligase UBR4

2

0

High-throughput

0.328

High

351608

TTL
Tubulin--tyrosine ligase

2

0

High-throughput

0.328

High

351611

KLH15
Kelch-like protein 15

2

0

High-throughput

0.328

High

252954

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.316

High

351594

SUOX
Sulfite oxidase, mitochondrial

2

0

High-throughput

0.316

High

351598

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.316

High

351606

VA0D2
V-type proton ATPase subunit d 2

2

0

High-throughput

0.316

High

351609

IKBD
NF-kappa-B inhibitor delta

2

0

High-throughput

0.316

High

351610

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

351612

THIOM
Thioredoxin, mitochondrial

2

0

High-throughput

0.316

High

351615

KLH42
Kelch-like protein 42

2

0

High-throughput

0.316

High

351600

THEM4
Acyl-coenzyme A thioesterase THEM4

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024