Protein: DEK
Protein DEK

Gene: DEK
Organism: Homo sapiens
Interactions: 150
UniProt ID: P35659

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

214121

SPOP
Speckle-type POZ protein

6

1

Small-scale

0.735

High

727359

CSK21
Casein kinase II subunit alpha

4

4

High-throughput

0.705

High

586597

CSK22
Casein kinase II subunit alpha'

4

4

High-throughput

0.699

High

727360

H31
Histone H3.1

5

4

Small-scale

0.699

High

727356

H4
Histone H4

3

1

Small-scale

0.656

High

244029

BRD4
Bromodomain-containing protein 4

3

3

High-throughput

0.640

High

727412

H2B1H
Histone H2B type 1-H

2

3

High-throughput

0.601

High

302972

HEXI1
Protein HEXIM1

2

0

High-throughput

0.585

High

727434

DAXX
Death domain-associated protein 6

2

0

Small-scale

0.585

High

346096

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

631362

BRD2
Bromodomain-containing protein 2

2

4

High-throughput

0.584

High

727357

H2B1C
Histone H2B type 1-C/E/F/G/I

2

3

High-throughput

0.584

High

63068

RHG42
Rho GTPase-activating protein 42

2

1

High-throughput

0.571

High

727385

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

3

High-throughput

0.571

High

727396

RHG24
Rho GTPase-activating protein 24

2

2

High-throughput

0.571

High

727433

RHG20
Rho GTPase-activating protein 20

2

2

High-throughput

0.571

High

226689

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

359713

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

0

High-throughput

0.559

High

727431

KIF15
Kinesin-like protein KIF15

2

2

Small-scale

0.549

High

727344

CDK8
Cyclin-dependent kinase 8

1

1

High-throughput

0.536

High

727392

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.536

High

727417

ARHGQ
Rho guanine nucleotide exchange factor 26

2

1

High-throughput

0.521

High

727352

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

1

High-throughput

0.515

High

727430

KI13B
Kinesin-like protein KIF13B

1

2

High-throughput

0.515

High

133351

NOP56
Nucleolar protein 56

1

0

High-throughput

0.513

High

197952

PHF1
PHD finger protein 1

1

0

High-throughput

0.513

High

649339

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

727366

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.513

High

727406

HDAC2
Histone deacetylase 2

1

0

Small-scale

0.513

High

727411

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

727419

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.513

High

727427

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.513

High

727429

TF7L2
Transcription factor 7-like 2

1

0

High-throughput

0.513

High

174676

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

727367

EP300
Histone acetyltransferase p300

1

3

Small-scale

0.501

High

727407

CBP
CREB-binding protein

1

3

Small-scale

0.501

High

727409

KAT2B
Histone acetyltransferase KAT2B

1

3

Small-scale

0.501

High

224763

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

0

High-throughput

0.493

High

727387

ULK3
Serine/threonine-protein kinase ULK3

1

2

High-throughput

0.489

High

727415

TRI63
E3 ubiquitin-protein ligase TRIM63

1

2

High-throughput

0.481

High

727422

TRI55
Tripartite motif-containing protein 55

1

2

High-throughput

0.481

High

369098

ESR1
Estrogen receptor

1

0

High-throughput

0.479

High

162449

XPO1
Exportin-1

1

1

High-throughput

0.479

High

239309

CC14B
Dual specificity protein phosphatase CDC14B

1

1

High-throughput

0.479

High

260776

H2AY
Core histone macro-H2A.1

1

2

Small-scale

0.479

High

267924

EED
Polycomb protein EED

1

3

High-throughput

0.479

High

308457

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.479

High

373793

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

379074

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

503557

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

569298

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

683874

1433S
14-3-3 protein sigma

1

1

Small-scale

0.479

High

727343

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

727345

CENPA
Histone H3-like centromeric protein A

1

4

High-throughput

0.479

High

727347

HDGF
Hepatoma-derived growth factor

1

2

High-throughput

0.479

High

727350

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.479

High

727353

WDR5
WD repeat-containing protein 5

1

2

High-throughput

0.479

High

727358

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.479

High

727361

H33
Histone H3.3

1

4

High-throughput

0.479

High

727369

FOXC1
Forkhead box protein C1

1

1

High-throughput

0.479

High

727374

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

727376

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

727378

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

727379

BRD3
Bromodomain-containing protein 3

1

4

High-throughput

0.479

High

727380

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

727382

H2A2C
Histone H2A type 2-C

1

2

Small-scale

0.479

High

727383

H2B2E
Histone H2B type 2-E

1

3

Small-scale

0.479

High

727386

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

1

1

High-throughput

0.479

High

727390

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.479

High

727395

SRRM1
Serine/arginine repetitive matrix protein 1

1

1

Small-scale

0.479

High

727402

CSK23
Casein kinase II subunit alpha 3

1

4

High-throughput

0.479

High

727404

DNJC9
DnaJ homolog subfamily C member 9

1

1

High-throughput

0.479

High

727408

KAT6A
Histone acetyltransferase KAT6A

1

1

Small-scale

0.479

High

727413

FBXW7
F-box/WD repeat-containing protein 7

1

2

Small-scale

0.479

High

727420

H2A1J
Histone H2A type 1-J

1

2

High-throughput

0.479

High

727436

BAZ1B
Tyrosine-protein kinase BAZ1B

1

6

Small-scale

0.479

High

119214

LEG9
Galectin-9

1

0

High-throughput

0.458

High

122527

MEN1
Menin

1

0

High-throughput

0.458

High

155287

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

177829

TMPS2
Transmembrane protease serine 2

1

0

High-throughput

0.458

High

209720

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

224330

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.458

High

233252

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

298220

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

322261

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

403601

AP2A
Transcription factor AP-2-alpha

1

0

Small-scale

0.458

High

441913

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

552087

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

625179

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

650518

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

717494

BMI1
Polycomb complex protein BMI-1

1

0

Small-scale

0.458

High

719827

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

727349

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

727354

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

727355

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

727363

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

727364

H11
Histone H1.1

1

0

Small-scale

0.458

High

727365

UBE3A
Ubiquitin-protein ligase E3A

1

0

High-throughput

0.458

High

727368

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

727370

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

727372

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

0

High-throughput

0.458

High

727373

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

727377

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

727384

MIDN
Midnolin

1

0

High-throughput

0.458

High

727389

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

727393

ARMC8
Armadillo repeat-containing protein 8

1

0

High-throughput

0.458

High

727394

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

727399

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.458

High

727403

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

727410

RENT1
Regulator of nonsense transcripts 1

1

0

Small-scale

0.458

High

727414

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

727416

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

727418

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

727424

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

727432

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

727435

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

727437

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

0

High-throughput

0.458

High

727439

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

727351

CDC42
Cell division control protein 42 homolog

1

3

High-throughput

0.457

High

330883

PAK4
Serine/threonine-protein kinase PAK 4

1

1

High-throughput

0.445

High

401529

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

727371

STF1
Steroidogenic factor 1

1

3

Small-scale

0.445

High

148465

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.437

High

255555

OBSL1
Obscurin-like protein 1

1

1

High-throughput

0.437

High

456812

FURIN
Furin

1

1

High-throughput

0.437

High

727388

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

727391

TAXB1
Tax1-binding protein 1

1

1

High-throughput

0.437

High

727425

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

727438

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

484433

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.426

High

496445

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

528681

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

532406

TCTP
Translationally-controlled tumor protein

1

0

Small-scale

0.426

High

727362

SRSF2
Serine/arginine-rich splicing factor 2

1

0

Small-scale

0.426

High

727423

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

727426

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

727346

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

727381

H31T
Histone H3.1t

1

4

High-throughput

0.408

High

727400

GPT11
G patch domain-containing protein 11

2

0

High-throughput

0.316

High

727421

ACE2
Angiotensin-converting enzyme 2

2

0

High-throughput

0.305

High

727398

SH2D3
SH2 domain-containing protein 3C

2

0

High-throughput

0.298

High

727397

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.279

Low

241233

PRAM2
PRAME family member 2

1

0

Small-scale

0.249

Low

351959

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

726067

BASI
Basigin

1

0

High-throughput

0.249

Low

727348

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.249

Low

727375

CUL7
Cullin-7

1

0

High-throughput

0.249

Low

727401

CC112
Coiled-coil domain-containing protein 112

1

0

High-throughput

0.249

Low

727405

SSH1
Protein phosphatase Slingshot homolog 1

1

0

High-throughput

0.249

Low

727428

LUC7L
Putative RNA-binding protein Luc7-like 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024