Interactor 1: O61444 (O61444)
mitogen-activated protein kinase kinase (EC 2.7.12.2)
Gene: Mkk4
Interactor 2: JNK (P92208)
Stress-activated protein kinase JNK (dJNK) (EC 2.7.11.24) (Protein basket)
Gene: bsk
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.63 | 1.00 | 0.796 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19888449, 19079254, unassigned4 |
| Identification Methods | affinity chromatography technology, two hybrid array, experimental interaction detection |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Pkinase |
| Common GO terms | GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0007254 - JNK cascade GO:0030424 - axon GO:0033209 - tumor necrosis factor-mediated signaling pathway and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
