Protein: PKHA5
Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)

Gene: PKHA5, PLEKHA5
Organism: Homo sapiens
Interactions: 231
UniProt ID: Q9HAU0

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0010314 - phosphatidylinositol-5-phosphate binding
GO:0014069 - postsynaptic density
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

350563

RASK
GTPase KRas

3

20

High-throughput

0.827

High

915984

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

1125525

PDZ11
PDZ domain-containing protein 11

4

20

Small-scale

0.699

High

905127

1433G
14-3-3 protein gamma

4

20

High-throughput

0.699

High

982514

1433F
14-3-3 protein eta

4

20

High-throughput

0.699

High

200789

ARHG9
Rho guanine nucleotide exchange factor 9

1

9

High-throughput

0.698

High

1045526

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

20

High-throughput

0.698

High

1296378

ASPP1
Apoptosis-stimulating of p53 protein 1

1

20

High-throughput

0.698

High

1334839

PKHA5
Pleckstrin homology domain-containing family A member 5

1

17

High-throughput

0.698

High

1334862

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

11

High-throughput

0.691

High

683724

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.667

High

942963

SRPK2
SRSF protein kinase 2

1

20

High-throughput

0.647

High

1334847

GINM1
Glycoprotein integral membrane protein 1

3

0

High-throughput

0.638

High

910040

1433E
14-3-3 protein epsilon

2

12

High-throughput

0.635

High

1334863

PKHA6
Pleckstrin homology domain-containing family A member 6

1

20

High-throughput

0.625

High

120649

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

166613

DCLK1
Serine/threonine-protein kinase DCLK1

1

18

High-throughput

0.618

High

171334

EPHB6
Ephrin type-B receptor 6

1

19

High-throughput

0.618

High

232987

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

5

High-throughput

0.618

High

253410

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

16

High-throughput

0.618

High

325893

LATS1
Serine/threonine-protein kinase LATS1

1

20

High-throughput

0.618

High

338998

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.618

High

348930

RASN
GTPase NRas

1

20

High-throughput

0.618

High

349655

RASH
GTPase HRas

1

20

High-throughput

0.618

High

411861

LCK
Tyrosine-protein kinase Lck

1

16

High-throughput

0.618

High

434015

LYN
Tyrosine-protein kinase Lyn

1

17

High-throughput

0.618

High

435765

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.618

High

508203

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.618

High

545625

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

568798

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

12

High-throughput

0.618

High

665661

EPHB2
Ephrin type-B receptor 2

1

20

High-throughput

0.618

High

725564

COPB2
Coatomer subunit beta'

1

10

Small-scale

0.618

High

835524

GSK3A
Glycogen synthase kinase-3 alpha

1

10

High-throughput

0.618

High

836000

GSK3B
Glycogen synthase kinase-3 beta

1

11

High-throughput

0.618

High

845743

RAB9A
Ras-related protein Rab-9A

1

16

High-throughput

0.618

High

852627

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

876505

AFAD
Afadin

1

20

High-throughput

0.618

High

892603

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

894450

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

900922

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

901245

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

913121

ARF6
ADP-ribosylation factor 6

1

16

High-throughput

0.618

High

914367

RB11A
Ras-related protein Rab-11A

1

5

High-throughput

0.618

High

921731

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

14

High-throughput

0.618

High

925629

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

940567

CXAR
Coxsackievirus and adenovirus receptor

1

10

High-throughput

0.618

High

951352

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

960413

CDK16
Cyclin-dependent kinase 16

1

12

High-throughput

0.618

High

997220

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

11

High-throughput

0.618

High

1044162

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

12

High-throughput

0.618

High

1070402

RAB35
Ras-related protein Rab-35

1

11

High-throughput

0.618

High

1071703

KS6A2
Ribosomal protein S6 kinase alpha-2

1

16

High-throughput

0.618

High

1072602

EPHA7
Ephrin type-A receptor 7

1

18

High-throughput

0.618

High

1136546

SPD2A
SH3 and PX domain-containing protein 2A

1

15

High-throughput

0.618

High

1166723

WDR82
WD repeat-containing protein 82

1

20

High-throughput

0.618

High

1183557

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1217987

KSR1
Kinase suppressor of Ras 1

1

20

High-throughput

0.618

High

1246175

COP1
E3 ubiquitin-protein ligase COP1

1

16

High-throughput

0.618

High

1269227

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.618

High

1273280

ARHG2
Rho guanine nucleotide exchange factor 2

1

20

Small-scale

0.618

High

1285194

SH3K1
SH3 domain-containing kinase-binding protein 1

1

20

High-throughput

0.618

High

1292228

AURKB
Aurora kinase B

1

16

High-throughput

0.618

High

1300670

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

20

High-throughput

0.618

High

1301712

TESK2
Dual specificity testis-specific protein kinase 2

1

4

High-throughput

0.618

High

1311598

RTKN
Rhotekin

1

4

High-throughput

0.618

High

1326744

WWTR1
WW domain-containing transcription regulator protein 1

1

17

High-throughput

0.618

High

1331328

PKHA4
Pleckstrin homology domain-containing family A member 4

1

18

High-throughput

0.618

High

1334841

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

1334845

ANLN
Anillin

1

8

High-throughput

0.618

High

1334846

LATS2
Serine/threonine-protein kinase LATS2

1

20

High-throughput

0.618

High

927545

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.611

High

716775

CTNA1
Catenin alpha-1

2

8

Small-scale

0.584

High

1051468

DCTN1
Dynactin subunit 1

2

20

High-throughput

0.584

High

1044706

FHL3
Four and a half LIM domains protein 3

2

19

High-throughput

0.558

High

230917

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

20

High-throughput

0.553

High

283033

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

20

High-throughput

0.553

High

297679

RHBT1
Rho-related BTB domain-containing protein 1

1

20

High-throughput

0.553

High

318225

DIRA3
GTP-binding protein Di-Ras3

1

16

High-throughput

0.553

High

564690

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.553

High

592019

RAB4A
Ras-related protein Rab-4A

1

9

High-throughput

0.553

High

600673

EPHA1
Ephrin type-A receptor 1

1

19

High-throughput

0.553

High

608137

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.553

High

793477

MUC18
Cell surface glycoprotein MUC18

1

9

High-throughput

0.553

High

872491

EPHA5
Ephrin type-A receptor 5

1

20

High-throughput

0.553

High

1018193

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

20

High-throughput

0.553

High

1076766

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.553

High

1081607

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.553

High

1153742

STYK1
Tyrosine-protein kinase STYK1

1

20

High-throughput

0.553

High

1240465

POC1A
POC1 centriolar protein homolog A

1

16

High-throughput

0.553

High

1296737

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.553

High

1330924

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.553

High

1334844

KI13B
Kinesin-like protein KIF13B

1

18

High-throughput

0.553

High

1334860

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

17

High-throughput

0.553

High

61879

CC88B
Coiled-coil domain-containing protein 88B

1

20

High-throughput

0.541

High

444482

K1C19
Keratin, type I cytoskeletal 19

1

7

High-throughput

0.541

High

729040

K1C20
Keratin, type I cytoskeletal 20

1

7

High-throughput

0.541

High

898199

MAX
Protein max

1

10

High-throughput

0.541

High

963422

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

20

High-throughput

0.541

High

1068669

PLEC
Plectin

1

19

High-throughput

0.541

High

1121461

CCD92
Coiled-coil domain-containing protein 92

1

1

High-throughput

0.541

High

1137852

CE350
Centrosome-associated protein 350

1

17

High-throughput

0.541

High

1199881

KTN1
Kinectin

1

20

High-throughput

0.541

High

1271310

EVPL
Envoplakin

1

20

High-throughput

0.541

High

1313532

CP250
Centrosome-associated protein CEP250

1

15

High-throughput

0.541

High

1334865

KIF3A
Kinesin-like protein KIF3A

1

18

High-throughput

0.541

High

165059

SC16A
Protein transport protein Sec16A

1

12

High-throughput

0.536

High

654056

MAP4
Microtubule-associated protein 4

1

18

High-throughput

0.536

High

672307

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

11

High-throughput

0.536

High

855736

KIF11
Kinesin-like protein KIF11

1

20

High-throughput

0.536

High

915281

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

9

High-throughput

0.536

High

960978

CLH1
Clathrin heavy chain 1

1

3

High-throughput

0.536

High

1050797

FHL2
Four and a half LIM domains protein 2

1

20

High-throughput

0.536

High

1069272

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

1

5

High-throughput

0.536

High

1085686

HIF1A
Hypoxia-inducible factor 1-alpha

1

2

High-throughput

0.536

High

1283592

TRI52
E3 ubiquitin-protein ligase TRIM52

1

9

High-throughput

0.536

High

1334867

KCTD3
BTB/POZ domain-containing protein KCTD3

2

9

Small-scale

0.533

High

1188194

KANL1
KAT8 regulatory NSL complex subunit 1

1

0

High-throughput

0.518

High

1334857

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

1

0

High-throughput

0.518

High

1086321

H31T
Histone H3.1t

1

6

High-throughput

0.515

High

365069

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

869541

ATN1
Atrophin-1

1

14

High-throughput

0.506

High

301328

MTCL2
Microtubule cross-linking factor 2

1

20

High-throughput

0.494

High

877454

LAMB2
Laminin subunit beta-2

1

7

High-throughput

0.494

High

1189145

CC186
Coiled-coil domain-containing protein 186

1

17

High-throughput

0.494

High

648607

CALL3
Calmodulin-like protein 3

1

2

High-throughput

0.489

High

1238119

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

16

High-throughput

0.489

High

1334856

PNMA2
Paraneoplastic antigen Ma2

1

1

High-throughput

0.489

High

868750

ATX1
Ataxin-1

1

0

High-throughput

0.484

High

569125

DESM
Desmin

1

16

High-throughput

0.481

High

1272355

RENT1
Regulator of nonsense transcripts 1

1

9

High-throughput

0.481

High

1334866

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

3

High-throughput

0.481

High

116909

KIF2A
Kinesin-like protein KIF2A

1

20

High-throughput

0.479

High

151199

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

20

High-throughput

0.479

High

163303

XPO1
Exportin-1

1

20

High-throughput

0.479

High

196509

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

8

High-throughput

0.479

High

206001

TGON2
Trans-Golgi network integral membrane protein 2

1

10

High-throughput

0.479

High

208297

DCX
Neuronal migration protein doublecortin

1

5

Small-scale

0.479

High

213010

STX6
Syntaxin-6

1

1

High-throughput

0.479

High

232521

KDM1A
Lysine-specific histone demethylase 1A

1

10

High-throughput

0.479

High

237318

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

5

High-throughput

0.479

High

264406

GGYF1
GRB10-interacting GYF protein 1

1

16

High-throughput

0.479

High

279715

FLOT1
Flotillin-1

1

10

High-throughput

0.479

High

305635

ZFPL1
Zinc finger protein-like 1

1

2

High-throughput

0.479

High

347930

MYC
Myc proto-oncogene protein

1

10

High-throughput

0.479

High

397512

ADT2
ADP/ATP translocase 2

1

8

Small-scale

0.479

High

409237

K2C8
Keratin, type II cytoskeletal 8

1

5

High-throughput

0.479

High

430341

PROF1
Profilin-1

1

5

High-throughput

0.479

High

443818

VIME
Vimentin

1

16

High-throughput

0.479

High

507243

LAMP1
Lysosome-associated membrane glycoprotein 1

1

4

High-throughput

0.479

High

522201

CADH1
Cadherin-1

1

9

High-throughput

0.479

High

547222

EZRI
Ezrin

1

20

High-throughput

0.479

High

567277

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

575851

VINC
Vinculin

1

10

High-throughput

0.479

High

647290

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

672900

CDC27
Cell division cycle protein 27 homolog

1

13

Small-scale

0.479

High

673521

MPIP2
M-phase inducer phosphatase 2

1

6

High-throughput

0.479

High

675232

CLIP1
CAP-Gly domain-containing linker protein 1

1

20

High-throughput

0.479

High

684333

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

717352

CTNB1
Catenin beta-1

1

20

High-throughput

0.479

High

910577

RS14
Small ribosomal subunit protein uS11

1

2

Small-scale

0.479

High

933624

TBA4A
Tubulin alpha-4A chain

1

13

High-throughput

0.479

High

975045

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

1017803

STX4
Syntaxin-4

1

6

High-throughput

0.479

High

1022996

CDC16
Cell division cycle protein 16 homolog

1

12

Small-scale

0.479

High

1038725

HDAC1
Histone deacetylase 1

1

7

High-throughput

0.479

High

1060620

ZN638
Zinc finger protein 638

1

15

High-throughput

0.479

High

1077124

MARE1
Microtubule-associated protein RP/EB family member 1

1

4

High-throughput

0.479

High

1080787

ZYX
Zyxin

1

14

High-throughput

0.479

High

1206058

MIB1
E3 ubiquitin-protein ligase MIB1

1

18

High-throughput

0.479

High

1218654

DEN6A
Protein DENND6A

1

1

High-throughput

0.479

High

1243947

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1256255

DEN1A
DENN domain-containing protein 1A

1

11

High-throughput

0.479

High

1256894

PARD3
Partitioning defective 3 homolog

1

20

High-throughput

0.479

High

1263460

SRS12
Serine/arginine-rich splicing factor 12

1

20

High-throughput

0.479

High

1269656

ESR2
Estrogen receptor beta

1

12

High-throughput

0.479

High

1285357

PF21A
PHD finger protein 21A

1

12

High-throughput

0.479

High

1290065

RNF31
E3 ubiquitin-protein ligase RNF31

1

11

High-throughput

0.479

High

1300440

RAB3I
Rab-3A-interacting protein

1

2

High-throughput

0.479

High

1310151

LZTS2
Leucine zipper putative tumor suppressor 2

1

20

High-throughput

0.479

High

1329090

VP33B
Vacuolar protein sorting-associated protein 33B

1

6

High-throughput

0.479

High

1330411

DNJC5
DnaJ homolog subfamily C member 5

1

16

High-throughput

0.479

High

1332627

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1334840

RC3H2
Roquin-2

1

20

High-throughput

0.479

High

1334843

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.479

High

1334850

ZRAN1
Ubiquitin thioesterase ZRANB1

1

14

High-throughput

0.479

High

1334851

LIMA1
LIM domain and actin-binding protein 1

1

17

High-throughput

0.479

High

1334852

CDC23
Cell division cycle protein 23 homolog

1

11

Small-scale

0.479

High

1334853

APC5
Anaphase-promoting complex subunit 5

1

1

Small-scale

0.479

High

1334855

RCOR1
REST corepressor 1

1

6

High-throughput

0.479

High

1334858

ZBT21
Zinc finger and BTB domain-containing protein 21

1

15

High-throughput

0.479

High

1334859

PPM1H
Protein phosphatase 1H

1

3

High-throughput

0.479

High

1334864

CBY1
Protein chibby homolog 1

1

3

High-throughput

0.479

High

1334848

RFOX1
RNA binding protein fox-1 homolog 1

1

20

High-throughput

0.462

High

1100936

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

1334854

APC4
Anaphase-promoting complex subunit 4

1

0

Small-scale

0.458

High

240188

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

4

High-throughput

0.445

High

718210

BMI1
Polycomb complex protein BMI-1

1

10

High-throughput

0.445

High

787309

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

12

High-throughput

0.445

High

965158

ANK2
Ankyrin-2

1

13

High-throughput

0.445

High

1200004

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

10

High-throughput

0.445

High

1299750

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

16

High-throughput

0.445

High

132597

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

178792

STX7
Syntaxin-7

1

6

High-throughput

0.437

High

670222

MARCS
Myristoylated alanine-rich C-kinase substrate

1

9

High-throughput

0.437

High

1084192

OCLN
Occludin

1

7

High-throughput

0.437

High

1148224

RNF43
E3 ubiquitin-protein ligase RNF43

1

9

High-throughput

0.437

High

1152111

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.437

High

1162120

RHDF2
Inactive rhomboid protein 2

1

4

High-throughput

0.437

High

1171773

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1173151

SYDE1
Rho GTPase-activating protein SYDE1

1

20

High-throughput

0.437

High

1188885

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.437

High

1203856

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

1230378

CXD3
Gap junction delta-3 protein

1

5

High-throughput

0.437

High

1252642

SHKB1
SH3KBP1-binding protein 1

1

9

Small-scale

0.437

High

1283067

CK052
Uncharacterized protein C11orf52

1

4

High-throughput

0.437

High

1334842

E41LA
Band 4.1-like protein 4A

1

20

High-throughput

0.437

High

1334849

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

4

High-throughput

0.437

High

1334861

MARE3
Microtubule-associated protein RP/EB family member 3

1

4

High-throughput

0.437

High

1121886

Q53SB5
Desmin

1

16

High-throughput

0.417

High

56742

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

8

High-throughput

0.407

High

225054

ZNRD2
Protein ZNRD2

2

0

High-throughput

0.328

High

204560

PROM1
Prominin-1

1

0

High-throughput

0.282

High

217205

EXTL3
Exostosin-like 3

1

0

High-throughput

0.282

High

1185294

3BP5L
SH3 domain-binding protein 5-like

1

0

High-throughput

0.282

High

1290943

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1293859

MR1L1
MORF4 family-associated protein 1-like 1

1

0

High-throughput

0.279

Low

1334868

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.279

Low

928691

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.249

Low

1229857

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.249

Low

1167099

Q6VEQ4
CXYorf1

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024