Protein: Q9W1M9
Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4)

Gene: Q9W1M9, Rrp4
Organism: Drosophila melanogaster
Interactions: 98
UniProt ID: Q9W1M9

Gene Ontology (top 5):
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000956 - nuclear-transcribed mRNA catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1479636

Q9VKJ4
Csl4

3

3

Small-scale

0.817

High

1487618

Q9VW53
FI01414p

3

20

Small-scale

0.817

High

1177511

Q29QQ9
Ribosomal RNA-processing protein 42

2

20

High-throughput

0.737

High

1305060

EXOS3
Exosome complex component RRP40

2

7

High-throughput

0.737

High

1475400

Q9VGZ2
FI06805p

2

20

High-throughput

0.737

High

1479003

Q9VK19
FI07225p

2

20

High-throughput

0.737

High

1470116

Q9VC93
Exosome complex exonuclease RRP44

4

9

Small-scale

0.672

High

1473867

EXOSX
Exosome complex component 10 homolog

3

7

Small-scale

0.633

High

1489628

SPT6H
Transcription elongation factor SPT6

1

1

Small-scale

0.618

High

1343274

Q8SWT2
RNA helicase

1

1

High-throughput

0.575

High

1345980

Q8T4A9
Exosome complex component RRP45

1

20

High-throughput

0.575

High

1489634

Q9Y134
RNA helicase

1

7

High-throughput

0.575

High

1376988

Q95PE4
GEO07784p1

1

4

High-throughput

0.514

High

1379107

SAP47
Synapse-associated protein of 47 kDa

1

0

High-throughput

0.486

High

1174393

CP190
Centrosome-associated zinc finger protein Cp190

1

1

Small-scale

0.479

High

1476139

Q9VHC7
FI21236p1

1

0

Small-scale

0.458

High

231889

DKC1
H/ACA ribonucleoprotein complex subunit 4

1

1

High-throughput

0.445

High

616677

ARM
Armadillo segment polarity protein

1

1

High-throughput

0.445

High

654925

MA205
205 kDa microtubule-associated protein

1

2

High-throughput

0.445

High

1196598

Q4V5H1
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.445

High

1264953

Q7K1Q7
Ribosome assembly factor mrt4

1

1

High-throughput

0.445

High

1273718

Q7PLL3
Eukaryotic initiation factor 4B

1

2

High-throughput

0.445

High

1303670

Q8IN95
Nuclear migration protein nudC

1

1

High-throughput

0.445

High

1320861

Q8MMD2
Epidermal growth factor receptor pathway substrate clone 15, isoform B

1

1

High-throughput

0.445

High

1463453

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

1

High-throughput

0.445

High

1468816

Q9VB04
Protein CASC3

1

1

High-throughput

0.445

High

1476748

Q9VHT5
Large ribosomal subunit protein uL1m

1

1

High-throughput

0.445

High

1477041

SMD2
Probable small nuclear ribonucleoprotein Sm D2

1

1

High-throughput

0.445

High

1488954

Q9VZ88
AT07585p

1

2

High-throughput

0.445

High

1489630

NSUN2
tRNA

1

2

High-throughput

0.445

High

1489631

DDB1
DNA damage-binding protein 1

1

1

High-throughput

0.445

High

402296

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

Small-scale

0.437

High

1465530

SPT5H
Transcription elongation factor SPT5

1

1

Small-scale

0.437

High

426858

HP1
Heterochromatin protein 1

1

0

High-throughput

0.426

High

1050953

SSRP1
FACT complex subunit Ssrp1

1

0

High-throughput

0.426

High

1463355

Q9V3D8
GH27579p

1

0

High-throughput

0.426

High

1466538

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

0

High-throughput

0.426

High

1477865

RAGP1
Ran GTPase-activating protein

1

0

High-throughput

0.426

High

1479997

Q9VKW8
U6 snRNA-associated Sm-like protein LSm4

1

0

High-throughput

0.426

High

1483362

Q9VPM0
GH06023p

1

0

High-throughput

0.426

High

1487128

SMN
Survival motor neuron protein

1

0

High-throughput

0.426

High

1488185

RUXG
Probable small nuclear ribonucleoprotein G

1

0

High-throughput

0.426

High

1488348

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

1488877

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

0

High-throughput

0.426

High

1488993

THUM1
THUMP domain-containing protein 1 homolog

1

0

High-throughput

0.426

High

1489621

Q9W1M6
Regulatory protein zeste

1

0

High-throughput

0.426

High

1489627

ZN593
Zinc finger protein 593 homolog

1

0

High-throughput

0.426

High

1489629

Q9W4J4
GM14292p

1

0

High-throughput

0.426

High

1489633

SYQ
Probable glutamine--tRNA ligase

1

0

High-throughput

0.426

High

1345092

WDR55
WD repeat-containing protein 55 homolog

1

4

High-throughput

0.407

High

1377815

EBI
F-box-like/WD repeat-containing protein ebi

1

4

High-throughput

0.407

High

1463925

WDS
Protein will die slowly

1

5

High-throughput

0.407

High

1469641

Q9VBT1
CHK kinase-like domain-containing protein

1

1

High-throughput

0.407

High

1476455

RM19
Large ribosomal subunit protein bL19m

1

1

High-throughput

0.407

High

1480333

Q9VL60
RE01590p

1

1

High-throughput

0.407

High

1482705

Q9VNF6
Metastasis-associated protein MTA3

1

1

High-throughput

0.407

High

1484431

Q9VQS4
Spindly

1

1

High-throughput

0.407

High

1486545

POC1
POC1 centriolar protein homolog

1

3

High-throughput

0.407

High

1487278

Q9VVF8
Uncharacterized protein, isoform A

1

1

High-throughput

0.407

High

1487308

Q9VVI0
SD09427p

1

4

High-throughput

0.407

High

1488783

Q9VYQ9
Pleiotropic regulator 1

1

5

High-throughput

0.407

High

1488822

Q9VYT3
FI23714p1

1

1

High-throughput

0.407

High

1489626

Q9W3J4
LD35215p

1

1

High-throughput

0.407

High

53202

A1Z7K8
AaRS-interacting multifunctional protein 1

1

0

High-throughput

0.232

Low

54989

A1Z917
PiggyBac transposable element-derived protein domain-containing protein

1

0

High-throughput

0.232

Low

56913

A1ZAK3
Protein DEK

1

0

High-throughput

0.232

Low

232021

O44226
Elongin-B

1

0

High-throughput

0.232

Low

726524

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

847946

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.232

Low

875149

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.232

Low

887830

MCM2
DNA replication licensing factor Mcm2

1

0

High-throughput

0.232

Low

925878

SET
Protein SET

1

0

High-throughput

0.232

Low

1019531

AP2A
AP-2 complex subunit alpha

1

0

High-throughput

0.232

Low

1195972

Q4QQ70
IP09819p

1

0

High-throughput

0.232

Low

1261442

Q7JQT8
LD41464p

1

0

High-throughput

0.232

Low

1264061

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.232

Low

1264324

Q7K0L8
FLICE-associated huge protein, isoform A

1

0

High-throughput

0.232

Low

1266581

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.232

Low

1304664

CPLX
Complexin

1

0

High-throughput

0.232

Low

1305540

Q8IQI3
Uncharacterized protein, isoform B

1

0

High-throughput

0.232

Low

1306375

SPT16
FACT complex subunit spt16

1

0

High-throughput

0.232

Low

1321798

Q8MT77
LD28489p

1

0

High-throughput

0.232

Low

1344583

Q8SYM9
FI04119p

1

0

High-throughput

0.232

Low

1440228

NASP
Nuclear autoantigenic sperm protein homolog

1

0

High-throughput

0.232

Low

1463948

RUVB2
RuvB-like helicase 2

1

0

High-throughput

0.232

Low

1476347

Q9VHM3
LD30467p

1

0

High-throughput

0.232

Low

1476597

Q9VHR5
Veneno

1

0

High-throughput

0.232

Low

1481404

Q9VM14
dihydrolipoyllysine-residue acetyltransferase

1

0

High-throughput

0.232

Low

1481615

Q9VM97
Thrombospondin, isoform A

1

0

High-throughput

0.232

Low

1483329

RM10
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.232

Low

1485540

DBR1
Lariat debranching enzyme

1

0

High-throughput

0.232

Low

1485879

QTRT2
Queuine tRNA-ribosyltransferase accessory subunit 2

1

0

High-throughput

0.232

Low

1485940

Q9VT38
GH03795p

1

0

High-throughput

0.232

Low

1486759

RM39
Large ribosomal subunit protein mL39

1

0

High-throughput

0.232

Low

1486936

Q9VUR4
FI11905p

1

0

High-throughput

0.232

Low

1489507

Q9W108
FI01540p

1

0

High-throughput

0.232

Low

1489577

Q9W1H6
GH04238p

1

0

High-throughput

0.232

Low

1489632

Q9Y0Y5
Coatomer subunit epsilon

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025