Protein: PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIase F) (EC 5.2.1.8) (Cyclophilin D) (CyP-D) (CypD) (Cyclophilin F) (Mitochondrial cyclophilin) (CyP-M) (Rotamase F)

Gene: PPIF
Organism: Homo sapiens
Interactions: 116
UniProt ID: P30405

Gene Ontology (top 5):
GO:0000413 - protein peptidyl-prolyl isomerization
GO:0002931 - response to ischemia
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

673674

PPIA
Peptidyl-prolyl cis-trans isomerase A

2

11

High-throughput

0.776

High

673734

ABI2
Abl interactor 2

4

2

High-throughput

0.705

High

673683

GRSF1
G-rich sequence factor 1

1

8

High-throughput

0.618

High

673721

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

3

High-throughput

0.618

High

673691

SYPL1
Synaptophysin-like protein 1

2

1

High-throughput

0.606

High

673743

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

2

6

High-throughput

0.606

High

673680

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

2

1

Small-scale

0.595

High

325047

AIFM1
Apoptosis-inducing factor 1, mitochondrial

2

3

High-throughput

0.584

High

673672

ARFP2
Arfaptin-2

2

0

High-throughput

0.580

High

386169

P53
Cellular tumor antigen p53

1

4

Small-scale

0.578

High

673703

BANP
Protein BANP

2

2

High-throughput

0.578

High

673695

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

7

High-throughput

0.571

High

262724

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

673692

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

439101

SYPH
Synaptophysin

2

1

High-throughput

0.553

High

554273

MUC1
Mucin-1

2

4

High-throughput

0.553

High

673666

MAGAB
Melanoma-associated antigen 11

2

3

High-throughput

0.553

High

673710

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.549

High

449204

LEG1
Galectin-1

1

2

High-throughput

0.536

High

547722

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

5

High-throughput

0.536

High

673661

MYH9
Myosin-9

1

1

High-throughput

0.536

High

673679

KPCZ
Protein kinase C zeta type

1

3

High-throughput

0.536

High

673693

RHG31
Rho GTPase-activating protein 31

2

3

High-throughput

0.521

High

673669

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

1

0

High-throughput

0.513

High

394185

A4
Amyloid-beta precursor protein

1

3

Small-scale

0.501

High

518092

ADT1
ADP/ATP translocase 1

1

2

Small-scale

0.501

High

673660

CLIP1
CAP-Gly domain-containing linker protein 1

1

7

High-throughput

0.489

High

673730

ANLN
Anillin

1

3

High-throughput

0.489

High

673662

SPB5
Serpin B5

1

2

Small-scale

0.481

High

59120

VWA8
von Willebrand factor A domain-containing protein 8

1

3

High-throughput

0.479

High

242814

TRI13
E3 ubiquitin-protein ligase TRIM13

1

4

High-throughput

0.479

High

264850

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

269987

RF1M
Peptide chain release factor 1, mitochondrial

1

3

High-throughput

0.479

High

348530

RASN
GTPase NRas

1

7

High-throughput

0.479

High

349148

RASH
GTPase HRas

1

6

High-throughput

0.479

High

349911

RASK
GTPase KRas

1

6

High-throughput

0.479

High

440362

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

499561

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.479

High

503513

HSP7C
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.479

High

673663

MDHM
Malate dehydrogenase, mitochondrial

1

2

High-throughput

0.479

High

673665

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.479

High

673668

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.479

High

673670

EFTU
Elongation factor Tu, mitochondrial

1

3

High-throughput

0.479

High

673673

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

4

High-throughput

0.479

High

673676

TFAM
Transcription factor A, mitochondrial

1

3

High-throughput

0.479

High

673682

MPPA
Mitochondrial-processing peptidase subunit alpha

1

3

High-throughput

0.479

High

673684

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

7

High-throughput

0.479

High

673685

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.479

High

673687

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

4

High-throughput

0.479

High

673690

E2F4
Transcription factor E2F4

1

3

High-throughput

0.479

High

673698

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

1

High-throughput

0.479

High

673700

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

673702

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

4

High-throughput

0.479

High

673704

ESR2
Estrogen receptor beta

1

12

High-throughput

0.479

High

673705

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

7

High-throughput

0.479

High

673706

FAKD4
FAST kinase domain-containing protein 4

1

4

High-throughput

0.479

High

673707

MCUR1
Mitochondrial calcium uniporter regulator 1

1

1

High-throughput

0.479

High

673709

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.479

High

673714

EFGM
Elongation factor G, mitochondrial

1

7

High-throughput

0.479

High

673718

TR61B
tRNA

1

1

High-throughput

0.479

High

673719

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

1

High-throughput

0.479

High

673722

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

1

High-throughput

0.479

High

673724

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

2

High-throughput

0.479

High

673725

MTRFR
Mitochondrial translation release factor in rescue

1

3

High-throughput

0.479

High

673726

MTG2
Mitochondrial ribosome-associated GTPase 2

1

2

High-throughput

0.479

High

673727

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

673731

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

2

High-throughput

0.479

High

673733

RMND1
Required for meiotic nuclear division protein 1 homolog

1

1

High-throughput

0.479

High

673735

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

4

High-throughput

0.479

High

673737

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

3

High-throughput

0.479

High

673738

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

71781

FM25C
Protein FAM25C

1

3

High-throughput

0.470

High

673677

PRB3
Basic salivary proline-rich protein 3

1

5

High-throughput

0.470

High

63295

MET15
12S rRNA N4-methylcytidine

1

0

High-throughput

0.458

High

117356

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

0

High-throughput

0.458

High

172981

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

327368

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

336844

OTC
Ornithine transcarbamylase, mitochondrial

1

0

High-throughput

0.458

High

344942

CYTN
Cystatin-SN

1

0

Small-scale

0.458

High

486467

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

525430

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.458

High

673667

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

673678

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

673686

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.458

High

673688

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

673689

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

673694

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

673697

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

673708

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

673711

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

673712

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

673713

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.458

High

673715

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.458

High

673716

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

673717

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

673720

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

673723

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

673728

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

673729

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

673732

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

0

High-throughput

0.458

High

673736

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

673742

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

489374

BCL2
Apoptosis regulator Bcl-2

1

3

Small-scale

0.457

High

71762

FM25A
Protein FAM25A

1

3

High-throughput

0.439

High

673664

BCL6
B-cell lymphoma 6 protein

1

1

High-throughput

0.437

High

673671

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

3

High-throughput

0.437

High

673675

RHOG
Rho-related GTP-binding protein RhoG

1

8

High-throughput

0.437

High

673696

OTUD1
OTU domain-containing protein 1

1

1

High-throughput

0.437

High

673701

MEPCE
7SK snRNA methylphosphate capping enzyme

1

3

High-throughput

0.437

High

673741

UBP24
Ubiquitin carboxyl-terminal hydrolase 24

1

2

High-throughput

0.437

High

303881

YIF1A
Protein YIF1A

2

0

High-throughput

0.316

High

673699

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.316

High

673740

CIDEB
Lipid transferase CIDEB

2

0

High-throughput

0.316

High

173439

RER1
Protein RER1

1

0

High-throughput

0.279

Low

673681

QOR
Quinone oxidoreductase

1

0

High-throughput

0.249

Low

673739

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024