Protein: GRPE1
GrpE protein homolog 1, mitochondrial (HMGE) (Mt-GrpE#1)

Gene: GRPE1, GRPEL1
Organism: Homo sapiens
Interactions: 152
UniProt ID: Q9HAV7

Gene Ontology (top 5):
GO:0000774 - adenyl-nucleotide exchange factor activity
GO:0001405 - PAM complex, Tim23 associated import motor
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

751838

GRP75
Stress-70 protein, mitochondrial

5

5

High-throughput

0.925

High

1250782

GRPE2
GrpE protein homolog 2, mitochondrial

3

5

High-throughput

0.861

High

1334962

GRPE1
GrpE protein homolog 1, mitochondrial

3

5

Small-scale

0.855

High

1263184

PALLD
Palladin

3

0

High-throughput

0.638

High

1332221

DEN2D
DENN domain-containing protein 2D

3

0

High-throughput

0.638

High

1219012

HSC20
Iron-sulfur cluster co-chaperone protein HscB

2

1

High-throughput

0.611

High

529741

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.602

High

1202910

SPA24
Spermatogenesis-associated protein 24

2

0

High-throughput

0.602

High

169959

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

0

High-throughput

0.589

High

1051098

ICT1
Large ribosomal subunit protein mL62

2

0

High-throughput

0.585

High

347934

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

1086796

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

1

High-throughput

0.584

High

584277

ELK1
ETS domain-containing protein Elk-1

2

6

High-throughput

0.571

High

666179

SHC1
SHC-transforming protein 1

2

1

High-throughput

0.571

High

262975

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

1130607

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

0

High-throughput

0.547

High

845744

RAB9A
Ras-related protein Rab-9A

2

1

High-throughput

0.537

High

547851

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

1

High-throughput

0.536

High

1304295

EYA1
Eyes absent homolog 1

1

1

High-throughput

0.536

High

182213

PDPK1
3-phosphoinositide-dependent protein kinase 1

2

1

High-throughput

0.521

High

1031714

GRB10
Growth factor receptor-bound protein 10

2

1

High-throughput

0.521

High

1234561

SH2D3
SH2 domain-containing protein 3C

2

2

High-throughput

0.521

High

296623

TPPP
Tubulin polymerization-promoting protein

1

0

High-throughput

0.513

High

521308

SKI
Ski oncogene

1

0

High-throughput

0.513

High

646464

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.513

High

398096

ISG15
Ubiquitin-like protein ISG15

1

1

Small-scale

0.501

High

1048035

RB33A
Ras-related protein Rab-33A

1

1

High-throughput

0.489

High

976513

ERCC6
DNA excision repair protein ERCC-6

1

0

High-throughput

0.480

High

1282385

WBP2
WW domain-binding protein 2

1

0

Small-scale

0.480

High

258203

DNJB6
DnaJ homolog subfamily B member 6

1

8

High-throughput

0.479

High

265043

MPPB
Mitochondrial-processing peptidase subunit beta

1

2

High-throughput

0.479

High

279345

DNJB5
DnaJ homolog subfamily B member 5

1

2

High-throughput

0.479

High

374901

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

379885

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

440743

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

570077

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

592505

RAB5A
Ras-related protein Rab-5A

1

1

High-throughput

0.479

High

636521

DNJB2
DnaJ homolog subfamily B member 2

1

6

High-throughput

0.479

High

657862

ELK4
ETS domain-containing protein Elk-4

1

6

High-throughput

0.479

High

692189

ELF1
ETS-related transcription factor Elf-1

1

7

High-throughput

0.479

High

777748

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

781152

ETV5
ETS translocation variant 5

1

7

High-throughput

0.479

High

785411

ELK3
ETS domain-containing protein Elk-3

1

7

High-throughput

0.479

High

794569

ETV4
ETS translocation variant 4

1

7

High-throughput

0.479

High

803239

IF2M
Translation initiation factor IF-2, mitochondrial

1

3

High-throughput

0.479

High

827600

EFTU
Elongation factor Tu, mitochondrial

1

2

High-throughput

0.479

High

944629

ELF3
ETS-related transcription factor Elf-3

1

7

High-throughput

0.479

High

1014509

MPPA
Mitochondrial-processing peptidase subunit alpha

1

2

High-throughput

0.479

High

1043235

CUL4A
Cullin-4A

1

1

High-throughput

0.479

High

1067474

EEA1
Early endosome antigen 1

1

1

High-throughput

0.479

High

1152974

MRM1
rRNA methyltransferase 1, mitochondrial

1

1

High-throughput

0.479

High

1192101

DNJB7
DnaJ homolog subfamily B member 7

1

8

High-throughput

0.479

High

1245923

DNJB8
DnaJ homolog subfamily B member 8

1

9

High-throughput

0.479

High

1262165

DNJA4
DnaJ homolog subfamily A member 4

1

3

High-throughput

0.479

High

1262561

DNJB3
DnaJ homolog subfamily B member 3

1

8

High-throughput

0.479

High

1284529

MCUR1
Mitochondrial calcium uniporter regulator 1

1

2

High-throughput

0.479

High

1286857

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.479

High

1290504

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

3

High-throughput

0.479

High

1297254

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

9

High-throughput

0.479

High

1304307

EYA3
Eyes absent homolog 3

1

1

High-throughput

0.479

High

1326591

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

2

High-throughput

0.479

High

1331125

MTG2
Mitochondrial ribosome-associated GTPase 2

1

1

High-throughput

0.479

High

1334963

DNJC4
DnaJ homolog subfamily C member 4

1

9

High-throughput

0.479

High

1334966

DJC11
DnaJ homolog subfamily C member 11

1

9

High-throughput

0.479

High

1334970

DJC27
DnaJ homolog subfamily C member 27

1

1

High-throughput

0.479

High

59316

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

325404

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.458

High

354564

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

360430

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

373428

CATA
Catalase

1

0

High-throughput

0.458

High

385545

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

485089

GLI2
Zinc finger protein GLI2

1

0

High-throughput

0.458

High

486644

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

583368

HXK1
Hexokinase-1

1

0

High-throughput

0.458

High

637564

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.458

High

648890

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

673628

MPIP3
M-phase inducer phosphatase 3

1

0

High-throughput

0.458

High

719158

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

749864

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

772166

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

799368

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

868336

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

869747

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.458

High

881029

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

896228

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

916879

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

935256

H31
Histone H3.1

1

0

High-throughput

0.458

High

959055

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

981433

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

990319

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1020570

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

1045868

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

1116555

LARP7
La-related protein 7

1

0

High-throughput

0.458

High

1128258

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1148793

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1220158

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

0

High-throughput

0.458

High

1292229

AURKB
Aurora kinase B

1

0

High-throughput

0.458

High

1299474

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1301150

EFGM
Elongation factor G, mitochondrial

1

0

High-throughput

0.458

High

1302847

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.458

High

1305887

SMAD5
Mothers against decapentaplegic homolog 5

1

0

High-throughput

0.458

High

1315025

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1317132

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1329805

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1333090

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1333359

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1334151

SFXN1
Sideroflexin-1

1

0

High-throughput

0.458

High

1334964

ANM8
Protein arginine N-methyltransferase 8

1

0

Small-scale

0.458

High

1334965

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.458

High

1334967

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

0

High-throughput

0.458

High

1334971

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1334972

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

0

High-throughput

0.458

High

1334973

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1334976

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

402491

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

781661

ETV6
Transcription factor ETV6

1

5

High-throughput

0.437

High

995231

GOGA2
Golgin subfamily A member 2

1

1

High-throughput

0.437

High

1148492

LHX8
LIM/homeobox protein Lhx8

1

1

High-throughput

0.437

High

1167898

DJC14
DnaJ homolog subfamily C member 14

1

9

High-throughput

0.437

High

1252947

DJB14
DnaJ homolog subfamily B member 14

1

7

High-throughput

0.437

High

1281185

LHX4
LIM/homeobox protein Lhx4

1

1

High-throughput

0.437

High

1333325

DJC18
DnaJ homolog subfamily C member 18

1

9

High-throughput

0.437

High

1334968

DJB12
DnaJ homolog subfamily B member 12

1

8

High-throughput

0.437

High

1334974

DJC16
DnaJ homolog subfamily C member 16

1

8

High-throughput

0.437

High

1334975

NINL
Ninein-like protein

1

1

High-throughput

0.437

High

906142

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

High-throughput

0.426

High

958772

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.426

High

1301387

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

1318851

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

1203385

PRSR2
Proline and serine-rich protein 2

2

0

High-throughput

0.328

High

432473

GALT
Galactose-1-phosphate uridylyltransferase

2

0

High-throughput

0.316

High

1102802

CCD57
Coiled-coil domain-containing protein 57

2

0

High-throughput

0.316

High

1334969

SPG21
Maspardin

2

0

High-throughput

0.316

High

914369

RB11A
Ras-related protein Rab-11A

2

0

High-throughput

0.307

High

1285195

SH3K1
SH3 domain-containing kinase-binding protein 1

2

0

High-throughput

0.298

High

1298757

SCLT1
Sodium channel and clathrin linker 1

2

0

High-throughput

0.298

High

456295

IFIT1
Interferon-induced protein with tetratricopeptide repeats 1

1

0

High-throughput

0.279

Low

473072

BNIP5
Protein BNIP5

1

0

High-throughput

0.279

Low

1251923

RIN3
Ras and Rab interactor 3

1

0

High-throughput

0.279

Low

1334977

MTL5
Tesmin

1

0

High-throughput

0.279

Low

169616

BET1
BET1 homolog

1

0

High-throughput

0.249

Low

382152

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.249

Low

507244

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.249

Low

719620

MERL
Merlin

1

0

High-throughput

0.249

Low

951354

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.249

Low

1021352

FOXL1
Forkhead box protein L1

1

0

High-throughput

0.249

Low

1026364

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

Small-scale

0.249

Low

1060285

NFAC4
Nuclear factor of activated T-cells, cytoplasmic 4

1

0

High-throughput

0.249

Low

1171778

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1331331

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1047267

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024