Protein: VPP2
V-type proton ATPase 116 kDa subunit a 2 (V-ATPase 116 kDa subunit a 2) (Lysosomal H(+)-transporting ATPase V0 subunit a 2) (TJ6) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2)

Gene: VPP2, ATP6V0A2
Organism: Homo sapiens
Interactions: 120
UniProt ID: Q9Y487

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain
GO:0001669 - acrosomal vesicle
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

648093

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

3

9

High-throughput

0.861

High

900021

VA0D1
V-type proton ATPase subunit d 1

3

12

High-throughput

0.861

High

175622

VA0E1
V-type proton ATPase subunit e 1

2

3

High-throughput

0.811

High

1274159

VPP1
V-type proton ATPase 116 kDa subunit a 1

2

6

High-throughput

0.811

High

597747

VATC1
V-type proton ATPase subunit C 1

2

8

High-throughput

0.789

High

736135

VATE1
V-type proton ATPase subunit E 1

2

5

High-throughput

0.789

High

1237964

VA0D2
V-type proton ATPase subunit d 2

2

12

High-throughput

0.789

High

275149

RENR
Renin receptor

4

4

High-throughput

0.699

High

1035691

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

6

High-throughput

0.691

High

1335304

VPP4
V-type proton ATPase 116 kDa subunit a 4

1

6

High-throughput

0.691

High

1079869

VAS1
V-type proton ATPase subunit S1

3

5

High-throughput

0.675

High

1088410

VATF
V-type proton ATPase subunit F

3

6

High-throughput

0.675

High

554385

MUC1
Mucin-1

3

2

High-throughput

0.667

High

597713

VATB2
V-type proton ATPase subunit B, brain isoform

3

9

High-throughput

0.667

High

793539

MUC18
Cell surface glycoprotein MUC18

3

4

High-throughput

0.667

High

1234103

TM199
Transmembrane protein 199

3

4

High-throughput

0.667

High

1298847

CC115
Coiled-coil domain-containing protein 115

3

3

High-throughput

0.667

High

547374

VATB1
V-type proton ATPase subunit B, kidney isoform

3

9

High-throughput

0.656

High

314461

NPT2B
Sodium-dependent phosphate transport protein 2B

2

1

High-throughput

0.628

High

353314

CD4
T-cell surface glycoprotein CD4

2

1

High-throughput

0.628

High

823298

MRP
MARCKS-related protein

2

1

High-throughput

0.628

High

842280

BCAM
Basal cell adhesion molecule

2

4

High-throughput

0.628

High

1132989

CSCL2
CSC1-like protein 2

2

3

High-throughput

0.628

High

1239543

AT11C
Phospholipid-transporting ATPase IG

2

3

High-throughput

0.628

High

1357086

FZD10
Frizzled-10

2

1

High-throughput

0.628

High

1377794

VATD
V-type proton ATPase subunit D

2

5

High-throughput

0.628

High

318304

VATG2
V-type proton ATPase subunit G 2

1

7

High-throughput

0.618

High

354913

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

2

1

High-throughput

0.611

High

1152218

LTOR1
Ragulator complex protein LAMTOR1

2

1

Small-scale

0.611

High

121233

LEG8
Galectin-8

3

6

High-throughput

0.609

High

1114077

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

3

3

High-throughput

0.609

High

1244231

T185A
Transmembrane protein 185A

3

1

High-throughput

0.609

High

1301970

SERC2
Serine incorporator 2

3

1

High-throughput

0.609

High

236347

B4GT3
Beta-1,4-galactosyltransferase 3

2

0

High-throughput

0.602

High

850354

CLCN6
H(+)/Cl(-) exchange transporter 6

2

0

High-throughput

0.602

High

1264966

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

2

0

High-throughput

0.602

High

1303455

CYH2
Cytohesin-2

2

4

Small-scale

0.595

High

1127222

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

2

High-throughput

0.574

High

1223576

K2013
Uncharacterized protein KIAA2013

2

4

High-throughput

0.574

High

370793

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

537329

DRD2
D(2) dopamine receptor

1

1

High-throughput

0.541

High

62226

ARRD5
Arrestin domain-containing protein 5

1

1

High-throughput

0.536

High

206442

LTOR5
Ragulator complex protein LAMTOR5

1

1

High-throughput

0.536

High

365254

FRIH
Ferritin heavy chain

1

1

High-throughput

0.536

High

505507

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

1

High-throughput

0.536

High

873329

EMP3
Epithelial membrane protein 3

1

1

High-throughput

0.536

High

874716

AQP5
Aquaporin-5

1

4

High-throughput

0.536

High

896701

RAB14
Ras-related protein Rab-14

1

2

High-throughput

0.536

High

918973

RAB1A
Ras-related protein Rab-1A

1

2

High-throughput

0.536

High

1032074

UT1
Urea transporter 1

1

1

High-throughput

0.536

High

1079477

VAMP3
Vesicle-associated membrane protein 3

1

5

High-throughput

0.536

High

1139814

PLPP4
Phospholipid phosphatase 4

1

1

High-throughput

0.536

High

1205406

STX12
Syntaxin-12

1

2

High-throughput

0.536

High

1260996

SFT2A
Vesicle transport protein SFT2A

1

1

High-throughput

0.536

High

1328162

RAB1B
Ras-related protein Rab-1B

1

1

High-throughput

0.536

High

1347991

M4A12
Membrane-spanning 4-domains subfamily A member 12

1

1

High-throughput

0.536

High

1349069

GPC5D
G-protein coupled receptor family C group 5 member D

1

1

High-throughput

0.536

High

670417

AQP1
Aquaporin-1

1

4

High-throughput

0.515

High

253768

AUXI
Auxilin

1

0

High-throughput

0.513

High

274163

CXB3
Gap junction beta-3 protein

1

0

High-throughput

0.513

High

274311

STK16
Serine/threonine-protein kinase 16

1

0

High-throughput

0.513

High

436121

ANXA6
Annexin A6

1

0

High-throughput

0.513

High

501440

CD8B
T-cell surface glycoprotein CD8 beta chain

1

0

High-throughput

0.513

High

503254

PPAL
Lysosomal acid phosphatase

1

0

High-throughput

0.513

High

603812

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.513

High

975130

CAV1
Caveolin-1

1

0

High-throughput

0.513

High

1125809

XKR4
XK-related protein 4

1

0

High-throughput

0.513

High

1134958

SYT6
Synaptotagmin-6

1

0

High-throughput

0.513

High

1349013

TREM2
Triggering receptor expressed on myeloid cells 2

1

0

High-throughput

0.513

High

1350274

PCD10
Protocadherin-10

1

0

High-throughput

0.513

High

216397

EDIL3
EGF-like repeat and discoidin I-like domain-containing protein 3

1

1

High-throughput

0.489

High

449395

LEG1
Galectin-1

1

6

High-throughput

0.489

High

591167

BTF3
Transcription factor BTF3

1

1

High-throughput

0.489

High

1168274

CERS6
Ceramide synthase 6

1

1

High-throughput

0.489

High

1204240

F131B
Protein FAM131B

1

1

High-throughput

0.489

High

1234885

TTC9C
Tetratricopeptide repeat protein 9C

1

3

High-throughput

0.489

High

1291832

CERS2
Ceramide synthase 2

1

1

High-throughput

0.489

High

1343845

ANLN
Anillin

1

1

High-throughput

0.489

High

1346334

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

1

1

High-throughput

0.489

High

1356025

TBD
Tubulin delta chain

1

1

High-throughput

0.489

High

168087

NPC1
NPC intracellular cholesterol transporter 1

1

4

High-throughput

0.479

High

206210

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

901082

RHOA
Transforming protein RhoA

1

4

High-throughput

0.479

High

926726

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

1

High-throughput

0.479

High

1234007

EMC5
ER membrane protein complex subunit 5

1

2

High-throughput

0.479

High

1255996

RN128
E3 ubiquitin-protein ligase RNF128

1

3

High-throughput

0.479

High

1330450

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.479

High

1377795

SAR1B
Small COPII coat GTPase SAR1B

1

4

High-throughput

0.479

High

256175

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

527906

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

Small-scale

0.458

High

682087

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

Small-scale

0.458

High

1087640

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

1245519

ZNRF2
E3 ubiquitin-protein ligase ZNRF2

1

0

Small-scale

0.458

High

119578

LEG9
Galectin-9

1

6

High-throughput

0.437

High

447309

HXB5
Homeobox protein Hox-B5

1

1

High-throughput

0.437

High

1129186

RNFT1
E3 ubiquitin-protein ligase RNFT1

1

4

High-throughput

0.437

High

1156755

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1172406

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1237045

EMC1
ER membrane protein complex subunit 1

1

2

High-throughput

0.437

High

1237119

RN148
RING finger protein 148

1

3

High-throughput

0.437

High

1240849

RN149
E3 ubiquitin-protein ligase RNF149

1

3

High-throughput

0.437

High

1328900

DJC25
DnaJ homolog subfamily C member 25

1

1

High-throughput

0.437

High

1344229

SAR1A
Small COPII coat GTPase SAR1A

1

6

High-throughput

0.437

High

623408

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

2

0

High-throughput

0.328

High

1139971

SPRY7
SPRY domain-containing protein 7

2

0

High-throughput

0.328

High

1204623

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

2

0

High-throughput

0.328

High

1356981

TMCC3
Transmembrane and coiled-coil domain protein 3

2

0

High-throughput

0.328

High

351866

PAHO
Pancreatic polypeptide prohormone

1

0

High-throughput

0.279

Low

514507

PSPC
Surfactant protein C

1

0

High-throughput

0.279

Low

654928

CALX
Calnexin

1

0

High-throughput

0.279

Low

678111

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.279

Low

961891

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.279

Low

1121848

KCP3
Keratinocyte-associated protein 3

1

0

High-throughput

0.279

Low

1149034

STUM
Protein stum homolog

1

0

High-throughput

0.279

Low

1160340

ERIC5
Glutamate-rich protein 5

1

0

High-throughput

0.279

Low

1174569

CYS1
Cystin-1

1

0

High-throughput

0.279

Low

1268041

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.279

Low

1333674

PAAT
ATPase PAAT

1

0

High-throughput

0.279

Low

1377796

COX11
Cytochrome c oxidase assembly protein COX11, mitochondrial

1

0

High-throughput

0.279

Low

1346222

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024