Protein: CILK1
Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Ciliogenesis associated kinase 1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK)

Gene: CILK1
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q9UPZ9

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

322120

CDK14
Cyclin-dependent kinase 14

3

18

High-throughput

0.861

High

443562

CDK1
Cyclin-dependent kinase 1

3

15

High-throughput

0.861

High

1025608

CDK16
Cyclin-dependent kinase 16

3

18

High-throughput

0.861

High

1387477

MSI2H
RNA-binding protein Musashi homolog 2

3

8

High-throughput

0.861

High

1106128

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

2

10

High-throughput

0.811

High

468922

HS90B
Heat shock protein HSP 90-beta

2

15

High-throughput

0.802

High

462051

HS90A
Heat shock protein HSP 90-alpha

2

14

High-throughput

0.789

High

703748

MK01
Mitogen-activated protein kinase 1

2

13

Small-scale

0.754

High

956699

CKS1
Cyclin-dependent kinases regulatory subunit 1

2

20

High-throughput

0.726

High

1316647

CDK20
Cyclin-dependent kinase 20

1

17

Small-scale

0.724

High

856990

BAG6
Large proline-rich protein BAG6

1

5

Small-scale

0.692

High

174847

MAST4
Microtubule-associated serine/threonine-protein kinase 4

1

14

High-throughput

0.691

High

1083462

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

1

High-throughput

0.691

High

1110424

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

12

High-throughput

0.691

High

1158603

CDC37
Hsp90 co-chaperone Cdc37

1

8

High-throughput

0.691

High

1335963

ZBT44
Zinc finger and BTB domain-containing protein 44

1

1

High-throughput

0.691

High

1404611

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

4

High-throughput

0.691

High

1117530

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

7

High-throughput

0.665

High

245019

KATIP
Katanin-interacting protein

3

1

High-throughput

0.662

High

1149284

NR0B2
Nuclear receptor subfamily 0 group B member 2

3

5

High-throughput

0.662

High

1462641

CILK1
Serine/threonine-protein kinase ICK

1

17

Small-scale

0.647

High

1449668

F217B
Protein FAM217B

3

0

High-throughput

0.638

High

1322170

CENPL
Centromere protein L

3

0

High-throughput

0.634

High

132528

CDC7
Cell division cycle 7-related protein kinase

1

19

Small-scale

0.618

High

635014

MAK
Serine/threonine-protein kinase MAK

1

17

High-throughput

0.618

High

640331

EPHA1
Ephrin type-A receptor 1

1

7

High-throughput

0.618

High

1194458

LARP7
La-related protein 7

1

11

High-throughput

0.618

High

1416482

LS14B
Protein LSM14 homolog B

3

1

High-throughput

0.609

High

1446183

A4GAT
Lactosylceramide 4-alpha-galactosyltransferase

3

1

High-throughput

0.609

High

1462254

A4GCT
Alpha-1,4-N-acetylglucosaminyltransferase

3

1

High-throughput

0.609

High

423468

A4
Amyloid-beta precursor protein

2

6

High-throughput

0.602

High

1215449

DEP1A
DEP domain-containing protein 1A

2

0

High-throughput

0.602

High

1448459

SMYD2
N-lysine methyltransferase SMYD2

2

0

High-throughput

0.595

High

575767

IL1R1
Interleukin-1 receptor type 1

2

7

High-throughput

0.574

High

268944

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

2

3

High-throughput

0.558

High

908796

MAT1
CDK-activating kinase assembly factor MAT1

1

3

Small-scale

0.553

High

414868

P53
Cellular tumor antigen p53

1

6

High-throughput

0.536

High

709182

TPP2
Tripeptidyl-peptidase 2

1

1

High-throughput

0.536

High

1210385

NU188
Nucleoporin NUP188

1

0

High-throughput

0.513

High

1154028

SMAD1
Mothers against decapentaplegic homolog 1

1

3

High-throughput

0.508

High

1322675

RPTOR
Regulatory-associated protein of mTOR

1

7

Small-scale

0.501

High

1462642

FBX7
F-box only protein 7

1

3

High-throughput

0.501

High

1206260

PREP
Presequence protease, mitochondrial

1

2

High-throughput

0.489

High

325166

HEXI1
Protein HEXIM1

1

6

High-throughput

0.479

High

446089

ENOA
Alpha-enolase

1

3

High-throughput

0.479

High

935302

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

975525

PRS10
26S proteasome regulatory subunit 10B

1

3

High-throughput

0.479

High

1094488

IFT88
Intraflagellar transport protein 88 homolog

1

6

High-throughput

0.479

High

1326390

NIN
Ninein

1

16

High-throughput

0.479

High

1459143

IF172
Intraflagellar transport protein 172 homolog

1

4

High-throughput

0.479

High

635917

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

Small-scale

0.458

High

1383282

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

391524

FRIL
Ferritin light chain

1

1

High-throughput

0.445

High

756409

MCM7
DNA replication licensing factor MCM7

1

6

Small-scale

0.445

High

977612

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

11

High-throughput

0.445

High

97133

E9PNY5
Fc gamma receptor IIIb

1

1

High-throughput

0.407

High

1007419

S35A1
CMP-sialic acid transporter

2

0

High-throughput

0.328

High

611758

BMP7
Bone morphogenetic protein 7

2

0

High-throughput

0.318

High

1451190

TM45A
Transmembrane protein 45A

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025