Protein: RCC1
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)

Gene: RCC1
Organism: Homo sapiens
Interactions: 167
UniProt ID: P18754

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000785 - chromatin
GO:0000794 - condensed nuclear chromosome
GO:0003682 - chromatin binding
GO:0005085 - guanyl-nucleotide exchange factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

578412

RAN
GTP-binding nuclear protein Ran

16

8

Small-scale

0.986

High

134832

IMA3
Importin subunit alpha-3

5

2

Small-scale

0.929

High

131376

IMA4
Importin subunit alpha-4

4

2

Small-scale

0.899

High

578387

RANG
Ran-specific GTPase-activating protein

4

9

High-throughput

0.699

High

578435

IMB1
Importin subunit beta-1

5

0

Small-scale

0.692

High

243907

BRD4
Bromodomain-containing protein 4

4

4

High-throughput

0.676

High

578415

UBC9
SUMO-conjugating enzyme UBC9

3

10

High-throughput

0.675

High

63873

RGPD3
RanBP2-like and GRIP domain-containing protein 3

3

10

High-throughput

0.667

High

152761

RGPD8
RANBP2-like and GRIP domain-containing protein 8

3

10

High-throughput

0.667

High

578389

RAGP1
Ran GTPase-activating protein 1

3

1

High-throughput

0.667

High

578395

RBP2
E3 SUMO-protein ligase RanBP2

3

4

High-throughput

0.667

High

578460

NAV1
Neuron navigator 1

3

4

High-throughput

0.667

High

578469

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

3

10

High-throughput

0.667

High

578475

NUSAP
Nucleolar and spindle-associated protein 1

3

0

High-throughput

0.638

High

162391

XPO1
Exportin-1

2

5

Small-scale

0.629

High

578486

RANB3
Ran-binding protein 3

2

9

Small-scale

0.625

High

578446

H2B2E
Histone H2B type 2-E

2

6

Small-scale

0.619

High

578488

RCC2
Protein RCC2

1

13

High-throughput

0.618

High

578402

FOXA1
Hepatocyte nuclear factor 3-alpha

2

5

High-throughput

0.611

High

578441

DLGP5
Disks large-associated protein 5

2

0

High-throughput

0.602

High

391538

H2A1B
Histone H2A type 1-B/E

2

5

High-throughput

0.601

High

578384

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

5

High-throughput

0.600

High

578410

H4
Histone H4

2

3

Small-scale

0.595

High

345883

MYC
Myc proto-oncogene protein

2

4

High-throughput

0.584

High

578424

EP300
Histone acetyltransferase p300

2

6

High-throughput

0.584

High

578467

OTUB1
Ubiquitin thioesterase OTUB1

2

2

High-throughput

0.571

High

578481

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

2

3

High-throughput

0.571

High

578474

NTM1A
N-terminal Xaa-Pro-Lys N-methyltransferase 1

1

0

Small-scale

0.561

High

578379

RAB4A
Ras-related protein Rab-4A

1

1

High-throughput

0.553

High

578430

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.549

High

578378

VCAM1
Vascular cell adhesion protein 1

2

3

High-throughput

0.549

High

578392

KC1A
Casein kinase I isoform alpha

1

1

Small-scale

0.543

High

126428

FOXE1
Forkhead box protein E1

1

4

High-throughput

0.536

High

128432

DNM1L
Dynamin-1-like protein

1

2

High-throughput

0.536

High

176117

PPM1G
Protein phosphatase 1G

1

1

High-throughput

0.536

High

270762

FOXH1
Forkhead box protein H1

1

8

High-throughput

0.536

High

328730

TOP3B
DNA topoisomerase 3-beta-1

1

2

High-throughput

0.536

High

483381

RGPD1
RANBP2-like and GRIP domain-containing protein 1

1

11

High-throughput

0.536

High

578380

LMNB1
Lamin-B1

1

5

High-throughput

0.536

High

578394

NU153
Nuclear pore complex protein Nup153

1

14

High-throughput

0.536

High

578414

SUMO1
Small ubiquitin-related modifier 1

1

2

High-throughput

0.536

High

578416

CSK21
Casein kinase II subunit alpha

1

8

High-throughput

0.536

High

578436

NUMA1
Nuclear mitotic apparatus protein 1

1

3

High-throughput

0.536

High

578443

MARE1
Microtubule-associated protein RP/EB family member 1

1

2

High-throughput

0.536

High

578449

DJC21
DnaJ homolog subfamily C member 21

1

4

High-throughput

0.536

High

578454

FOXI2
Forkhead box protein I2

1

3

High-throughput

0.536

High

578471

FOXB1
Forkhead box protein B1

1

6

High-throughput

0.536

High

578478

FOXQ1
Forkhead box protein Q1

1

7

High-throughput

0.536

High

578482

FOXP1
Forkhead box protein P1

1

3

High-throughput

0.536

High

578492

HDAC9
Histone deacetylase 9

1

6

High-throughput

0.536

High

564792

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

Small-scale

0.527

High

578418

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

0

High-throughput

0.513

High

578423

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.513

High

578483

KDM4C
Lysine-specific demethylase 4C

1

0

High-throughput

0.513

High

148038

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

5

High-throughput

0.508

High

321700

WIZ
Protein Wiz

1

1

High-throughput

0.508

High

386063

P53
Cellular tumor antigen p53

1

6

High-throughput

0.508

High

537794

KPYM
Pyruvate kinase PKM

1

1

High-throughput

0.508

High

578398

APLP1
Amyloid beta precursor like protein 1

1

1

High-throughput

0.508

High

578405

ACTB
Actin, cytoplasmic 1

1

3

High-throughput

0.508

High

578413

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

4

High-throughput

0.508

High

578422

TLE1
Transducin-like enhancer protein 1

1

5

High-throughput

0.508

High

578425

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

6

High-throughput

0.508

High

578432

TBB3
Tubulin beta-3 chain

1

7

High-throughput

0.508

High

578456

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.508

High

578493

KMT2B
Histone-lysine N-methyltransferase 2B

1

3

High-throughput

0.508

High

578494

FAF1
FAS-associated factor 1

1

3

High-throughput

0.508

High

174612

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

8

High-throughput

0.501

High

578407

SUMO2
Small ubiquitin-related modifier 2

1

2

High-throughput

0.501

High

578417

H31
Histone H3.1

1

7

Small-scale

0.501

High

578421

ERCC6
DNA excision repair protein ERCC-6

1

2

High-throughput

0.501

High

578445

H2A2C
Histone H2A type 2-C

1

5

Small-scale

0.501

High

578381

FGFR2
Fibroblast growth factor receptor 2

1

4

High-throughput

0.500

High

578438

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.493

High

362798

FINC
Fibronectin

1

3

High-throughput

0.489

High

578406

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

5

High-throughput

0.489

High

578448

CCD93
Coiled-coil domain-containing protein 93

1

1

High-throughput

0.489

High

214844

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.486

High

279791

CDKA2
Cyclin-dependent kinase 2-associated protein 2

1

0

High-throughput

0.486

High

436606

TNR16
Tumor necrosis factor receptor superfamily member 16

1

0

High-throughput

0.486

High

505764

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.486

High

526805

HXD8
Homeobox protein Hox-D8

1

0

High-throughput

0.486

High

578400

ZN135
Zinc finger protein 135

1

0

High-throughput

0.486

High

578450

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.486

High

578470

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.486

High

578473

CAB45
45 kDa calcium-binding protein

1

0

High-throughput

0.486

High

578497

CSAD
Cysteine sulfinic acid decarboxylase

1

0

High-throughput

0.486

High

578390

BAG6
Large proline-rich protein BAG6

1

4

High-throughput

0.481

High

578495

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

119152

LEG9
Galectin-9

1

1

High-throughput

0.479

High

226478

PRKN
E3 ubiquitin-protein ligase parkin

1

13

High-throughput

0.479

High

233205

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

255494

OBSL1
Obscurin-like protein 1

1

4

High-throughput

0.479

High

260750

H2AY
Core histone macro-H2A.1

1

6

Small-scale

0.479

High

294347

RECQ4
ATP-dependent DNA helicase Q4

1

5

High-throughput

0.479

High

373653

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.479

High

381790

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.479

High

475320

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

12

Small-scale

0.479

High

551912

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

555286

H2AX
Histone H2AX

1

6

High-throughput

0.479

High

568174

TAL1
T-cell acute lymphocytic leukemia protein 1

1

4

Small-scale

0.479

High

578382

BRD2
Bromodomain-containing protein 2

1

10

High-throughput

0.479

High

578383

DNJB2
DnaJ homolog subfamily B member 2

1

3

High-throughput

0.479

High

578385

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

578386

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

578391

YAP1
Transcriptional coactivator YAP1

1

5

High-throughput

0.479

High

578396

GSK3A
Glycogen synthase kinase-3 alpha

1

6

High-throughput

0.479

High

578397

GSK3B
Glycogen synthase kinase-3 beta

1

6

High-throughput

0.479

High

578399

HDGF
Hepatoma-derived growth factor

1

2

High-throughput

0.479

High

578408

WDR5
WD repeat-containing protein 5

1

4

High-throughput

0.479

High

578409

NTF2
Nuclear transport factor 2

1

2

High-throughput

0.479

High

578411

H2B1C
Histone H2B type 1-C/E/F/G/I

1

6

High-throughput

0.479

High

578419

VIGLN
Vigilin

1

2

High-throughput

0.479

High

578420

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

578428

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.479

High

578429

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.479

High

578431

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

578433

CUL3
Cullin-3

1

8

High-throughput

0.479

High

578434

RBM39
RNA-binding protein 39

1

4

High-throughput

0.479

High

578437

CUL7
Cullin-7

1

4

High-throughput

0.479

High

578439

KIF14
Kinesin-like protein KIF14

1

4

High-throughput

0.479

High

578440

BRD3
Bromodomain-containing protein 3

1

10

High-throughput

0.479

High

578444

EZH2
Histone-lysine N-methyltransferase EZH2

1

3

High-throughput

0.479

High

578452

H2A2A
Histone H2A type 2-A

1

5

High-throughput

0.479

High

578455

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

578458

SMC5
Structural maintenance of chromosomes protein 5

1

4

High-throughput

0.479

High

578463

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

578464

ESR2
Estrogen receptor beta

1

9

High-throughput

0.479

High

578466

MBD6
Methyl-CpG-binding domain protein 6

1

5

High-throughput

0.479

High

578468

RING2
E3 ubiquitin-protein ligase RING2

1

6

High-throughput

0.479

High

578476

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

578480

WWTR1
WW domain-containing transcription regulator protein 1

1

5

High-throughput

0.479

High

578484

Q9H4D1
Protein kinase

1

4

High-throughput

0.479

High

578485

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.479

High

578489

MBD5
Methyl-CpG-binding domain protein 5

1

3

High-throughput

0.479

High

578490

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

578459

TRM2A
tRNA

1

1

High-throughput

0.464

High

214080

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

578388

NKX21
Homeobox protein Nkx-2.1

1

0

High-throughput

0.458

High

578426

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

578427

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

578442

TEAD2
Transcriptional enhancer factor TEF-4

1

0

High-throughput

0.458

High

578447

MIDN
Midnolin

1

0

High-throughput

0.458

High

578457

LYRIC
Protein LYRIC

1

0

Small-scale

0.458

High

578462

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

578487

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

578496

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

401390

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

578403

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

5

High-throughput

0.445

High

578472

VRK1
Serine/threonine-protein kinase VRK1

1

2

Small-scale

0.445

High

578479

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.445

High

148381

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.437

High

578451

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.437

High

578465

MFRN2
Mitoferrin-2

1

1

High-throughput

0.437

High

578491

SEC63
Translocation protein SEC63 homolog

1

2

High-throughput

0.437

High

414563

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

0

Small-scale

0.426

High

578393

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.408

High

147049

NEMP1
Nuclear envelope integral membrane protein 1

1

0

High-throughput

0.279

Low

578404

NU107
Nuclear pore complex protein Nup107

1

0

High-throughput

0.279

Low

326909

DDAH2
Putative hydrolase DDAH2

1

0

High-throughput

0.265

Low

393767

SCG1
Secretogranin-1

1

0

High-throughput

0.265

Low

578401

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.265

Low

578461

FAD1
FAD synthase

1

0

High-throughput

0.265

Low

329339

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

530414

ITA4
Integrin alpha-4

1

0

High-throughput

0.249

Low

578477

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low

578453

CREL2
Protein disulfide isomerase CRELD2

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024