Interactor 1: CSP3 (G5ECW5)
Non-catalytic caspase homolog csp-3
Gene: csp-3
Interactor 2: CED3 (P42573)
Cell death protein 3 (EC 3.4.22.60) (Caspase ced-3) [Cleaved into: Cell death protein 3 subunit p17; Cell death protein 3 subunit p15; Cell death protein 3 subunit p13]
Gene: ced-3
Species: Caenorhabditis elegans
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 1.00 | 0.761 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18776901 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, protease assay, pull down |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Peptidase_C14~Peptidase_C14 |
| Common GO terms | GO:0004197 - cysteine-type endopeptidase activity GO:0005737 - cytoplasm GO:0006508 - proteolysis GO:1904747 - positive regulation of apoptotic process involved in development |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025