Protein: PUR6
Probable multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)]

Gene: PUR6, pacs-1
Organism: Caenorhabditis elegans
Interactions: 25
UniProt ID: Q10457

Gene Ontology (top 5):
GO:0004638 - phosphoribosylaminoimidazole carboxylase activity
GO:0004639 - phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006189 - 'de novo' IMP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1013889

PUR6
Probable multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase

1

6

High-throughput

0.733

High

106659

SRC1
Tyrosine protein-kinase src-1

1

0

High-throughput

0.486

High

136573

O01661
Guanylate kinase/L-type calcium channel beta subunit domain-containing protein

1

1

High-throughput

0.464

High

711200

YKA7
Uncharacterized protein B0303.7

1

2

High-throughput

0.464

High

1013890

Q18204
SH3 domain-containing protein

1

4

High-throughput

0.464

High

1013896

Q95XW5
MAGUK family

1

1

High-throughput

0.464

High

1013897

Q9N415
Variant SH3 domain protein

1

1

High-throughput

0.464

High

1013898

CED2
Cell death abnormality protein 2

1

2

High-throughput

0.464

High

1013899

Q9U2T9
Intersectin-1

1

1

High-throughput

0.464

High

104633

ARK1
Ack-related non-receptor tyrosine kinase

1

2

High-throughput

0.457

High

107110

G5EEQ7
SH3 domain-containing protein

1

1

High-throughput

0.439

High

1013894

Q86DC0
SAM domain-containing protein

1

1

High-throughput

0.439

High

3048

MLK1
Mitogen-activated protein kinase kinase kinase mlk-1

1

0

High-throughput

0.438

High

105225

G5ECK4
SH3 domain-containing GRB2-like protein

1

2

High-throughput

0.417

High

1013891

Q18662
Caskin-2

1

3

High-throughput

0.417

High

103414

G4RZC8
PID domain-containing protein

1

0

High-throughput

0.265

Low

107479

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.265

Low

185077

NPHP1
Nephrocystin-1-like protein

1

0

High-throughput

0.265

Low

666209

SEM5
Sex muscle abnormal protein 5

1

0

High-throughput

0.265

Low

1013892

Q21004
Amphiphysin

1

0

High-throughput

0.265

Low

1013893

PLCG
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma plc-3

1

0

High-throughput

0.265

Low

1013895

Q8MQ71
SH3 domain-containing protein

1

0

High-throughput

0.265

Low

953912

LIN53
Probable histone-binding protein lin-53

1

0

High-throughput

0.249

Low

105558

DLG1
Disks large homolog 1

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024