Protein: FHIT
Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Adenosine 5'-monophosphoramidase FHIT) (EC 3.9.1.-) (Adenylylsulfatase) (EC 3.6.2.1) (Adenylylsulfate-ammonia adenylyltransferase) (EC 2.7.7.51) (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (Dinucleosidetriphosphatase) (Fragile histidine triad protein)

Gene: FHIT
Organism: Homo sapiens
Interactions: 21
UniProt ID: P49789

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0001650 - fibrillar center
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

890264

FHIT
Bis(5'-adenosyl)-triphosphatase

10

16

Small-scale

0.978

High

890269

RHG19
Rho GTPase-activating protein 19

2

0

High-throughput

0.602

High

764546

CTNB1
Catenin beta-1

1

2

Small-scale

0.589

High

890277

MTMR6
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6

2

0

High-throughput

0.585

High

890273

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.580

High

890276

LEF1
Lymphoid enhancer-binding factor 1

1

1

Small-scale

0.554

High

890265

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.549

High

783200

TRI23
E3 ubiquitin-protein ligase TRIM23

1

1

High-throughput

0.541

High

890268

RB40B
Ras-related protein Rab-40B

1

1

High-throughput

0.541

High

890267

REL
Proto-oncogene c-Rel

1

0

High-throughput

0.518

High

890272

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

297945

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.460

High

321465

PRP6
Pre-mRNA-processing factor 6

1

0

High-throughput

0.460

High

890274

YTHD1
YTH domain-containing family protein 1

1

0

High-throughput

0.460

High

890266

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

890275

RBL2A
Rab-like protein 2A

1

2

High-throughput

0.437

High

85420

B7ZBD5
RAB, member of RAS oncogene family like 2A

1

1

High-throughput

0.407

High

377850

GAST
Gastrin [Cleaved into: Gastrin-71

1

0

High-throughput

0.279

Low

890270

CBY2
Protein chibby homolog 2

1

0

High-throughput

0.279

Low

890271

FDSCP
Follicular dendritic cell secreted peptide

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025