Protein: Q9BIC1
Afadin

Gene: Q9BIC1, afd-1
Organism: Caenorhabditis elegans
Interactions: 33
UniProt ID: Q9BIC1

Gene Ontology (top 5):
GO:0005912 - adherens junction
GO:0007155 - cell adhesion
GO:0007165 - signal transduction
GO:0032880 - regulation of protein localization
GO:0050839 - cell adhesion molecule binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

145052

DLK1
Mitogen-activated protein kinase kinase kinase dlk-1

1

20

High-throughput

0.698

High

92525

D3YT29
PDZ domain-containing protein

1

19

Small-scale

0.621

High

144610

AIR2
Aurora/IPL1-related protein kinase 2

1

7

High-throughput

0.553

High

759034

PLK1
Serine/threonine-protein kinase plk-1

1

5

High-throughput

0.553

High

195550

O16511
Activated in Blocked Unfolded protein response

1

7

High-throughput

0.494

High

196360

EYA1
Protein phosphatase eya-1

1

5

High-throughput

0.494

High

759469

CHTB1
Chitin binding domain

1

12

High-throughput

0.494

High

1164825

Q17400
Activated in Blocked Unfolded protein response

1

6

High-throughput

0.494

High

1170850

Q22378
EB domain-containing protein

1

12

High-throughput

0.494

High

1301224

PDE3
Probable 3',5'-cyclic phosphodiesterase pde-3

1

2

High-throughput

0.494

High

1373884

CES2
Transcription factor ces-2

1

5

High-throughput

0.494

High

1409380

Q9N5S5
Potassium channel tetramerisation-type BTB domain-containing protein

1

19

High-throughput

0.494

High

113306

G5EFG1
PDZ and LIM domain protein Zasp

1

12

High-throughput

0.481

High

232039

HMP2
Beta-catenin-like protein hmp-2

1

20

Small-scale

0.479

High

1018796

HMP1
Alpha-catenin-like protein hmp-1

1

16

Small-scale

0.479

High

1379828

HMR1
Cadherin-related hmr-1

1

1

Small-scale

0.479

High

113433

G5EFL5
PDZ and LIM domain protein Zasp

1

13

High-throughput

0.457

High

1171339

FZO1
Transmembrane GTPase fzo-1

1

2

Small-scale

0.439

High

1180840

Q2XMY4
Trichohyalin

1

17

High-throughput

0.439

High

1306839

Q8ITW3
BZIP domain-containing protein

1

1

High-throughput

0.439

High

233109

O44490
ELKS/RAB6-interacting/CAST family member 2

1

19

High-throughput

0.437

High

111171

JUN
Transcription factor jun-1

1

7

High-throughput

0.417

High

116019

H2L0F6
BZIP domain-containing protein

1

1

High-throughput

0.417

High

1180837

Q2XMY3
Trichohyalin

1

16

High-throughput

0.417

High

234414

CSC1
Chromosome segregation and cytokinesis defective protein 1

1

0

High-throughput

0.304

High

115288

NSY7
Transcription factor nsy-7

1

0

High-throughput

0.282

High

196710

O18051
Coiled-coil domain-containing protein 146

1

0

High-throughput

0.282

High

1169746

Q20373
Uncharacterized protein

1

0

High-throughput

0.282

High

1171322

Q23390
Activated in Blocked Unfolded protein response

1

0

High-throughput

0.282

High

1201345

Q56VX2
BED-type domain-containing protein

1

0

High-throughput

0.282

High

1321862

Q8MYM0
C2H2-type domain-containing protein

1

0

High-throughput

0.282

High

1409379

Q9N4Z2
Nbl1_Borealin_N domain-containing protein

1

0

High-throughput

0.282

High

1409381

Q9TZ84
Ubiquitin-like domain-containing protein

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025