HitPredict

Interactor 1: D3YT29 (D3YT29)
PDZ domain-containing protein
Gene: magi-1

Interactor 2: Q9BIC1 (Q9BIC1)
Afadin
Gene: afd-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	22981773
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PDZ~PDZ
Common GO terms	GO:0005912 - adherens junction GO:0007165 - signal transduction GO:0032880 - regulation of protein localization
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 829 Ce			1 1658
+	Hs
		936419 MAGI1_HUMAN (2-638): 1.24e-43: 173: 14.80		AFAD_HUMAN (4-1526): 0: 597: 26.04
+	Hs
		246108 MAGI1_HUMAN (2-638): 1.24e-43: 173: 14.80		KIF1B_HUMAN (123-564): 1.35e-86: 316: 13.75
+	Hs
		230561 MAGI1_HUMAN (2-638): 1.24e-43: 173: 14.80		KIF1C_HUMAN (123-567): 4.04e-85: 306: 13.73
+	Hs
		1401115 MAGI1_HUMAN (2-638): 1.24e-43: 173: 14.80		KI13B_HUMAN (10-555): 1.5e-68: 258: 11.75
+	Hs
		299763 MPDZ_HUMAN (133-386): 2.19e-23: 109: 17.03		KIF14_HUMAN (10-708): 1.27e-66: 252: 12.29
+	Rn
		312761 DLG1_RAT (31-427): 4.25e-23: 107: 14.91		KIF1B_RAT (10-566): 1.55e-62: 239: 12.54
+	Mm
		1223740 MAGI3_MOUSE (147-766): 1.23e-40: 164: 14.75		DLG4_MOUSE (901-1058): 9.28e-17: 88.3: 23.27
+	Rn
		1224262 DLG1_RAT (31-427): 4.25e-23: 107: 14.91		DLG2_RAT (887-1330): 1.91e-31: 136: 13.19
+	Rn
		723902 NHRF3_RAT (590-827): 2.89e-26: 115: 21.43		DLG4_RAT (901-1058): 9.28e-17: 88.3: 23.27
+	Rn
		723883 DLG1_RAT (31-427): 4.25e-23: 107: 14.91		DLG4_RAT (901-1058): 9.28e-17: 88.3: 23.27
+	Hs
		299801 MPDZ_HUMAN (133-386): 2.19e-23: 109: 17.03		LIN7C_HUMAN (894-1063): 6.92e-18: 85.6: 22.03
+	Rn
		1224258 DLG1_RAT (31-427): 4.25e-23: 107: 14.91		DLG3_RAT (969-1045): 9.26e-14: 78.7: 26.58
+	Mm
		1223608 DLG1_MOUSE (647-829): 4.32e-18: 91.5: 23.00		DLG4_MOUSE (901-1058): 9.28e-17: 88.3: 23.27
+	Hs
		1006071 DLG2_HUMAN (693-829): 8.12e-18: 90.8: 23.40		DLG4_HUMAN (901-1058): 9.28e-17: 88.3: 23.27
+	Mm
		313202 DLG1_MOUSE (647-829): 4.32e-18: 91.5: 23.00		LIN7C_MOUSE (894-1063): 6.92e-18: 85.6: 22.03
+	Rn
		1022043 GRIP2_RAT (3-697): 2.16e-22: 105: 12.77		GRIP1_RAT (904-1076): 7.68e-10: 66.1: 17.14
+	Hs
		1152416 DLG2_HUMAN (693-829): 8.12e-18: 90.8: 23.40		DLG3_HUMAN (969-1045): 7.23e-14: 79.1: 26.58
+	Mm
		999796 DLG2_MOUSE (693-829): 7.15e-18: 90.8: 23.40		DLG3_MOUSE (969-1045): 8.87e-14: 78.7: 26.58
+	Hs
		1091503 DLG2_HUMAN (693-829): 8.12e-18: 90.8: 23.40		DLG1_HUMAN (924-1058): 4.12e-11: 70.2: 24.09