Protein: HMEN
Segmentation polarity homeobox protein engrailed

Gene: HMEN, en
Organism: Drosophila melanogaster
Interactions: 24
UniProt ID: P02836

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

393684

GROU
Protein groucho

7

20

Small-scale

0.744

High

393682

GSBN
Protein gooseberry-neuro

1

20

Small-scale

0.713

High

393701

Q9W4I4
Helix loop helix protein 4C, isoform A

1

15

High-throughput

0.656

High

393687

ETS3
DNA-binding protein D-ETS-3

1

19

High-throughput

0.541

High

393689

HR78
Nuclear hormone receptor HR78

1

20

High-throughput

0.541

High

393694

Q9VAY8
Buddy of Hmr 1

1

15

High-throughput

0.541

High

393691

Q8SX32
type I protein arginine methyltransferase

1

6

High-throughput

0.508

High

393696

Q9VL91
LD23102p

1

5

High-throughput

0.508

High

235181

HTH
Homeobox protein homothorax

1

20

High-throughput

0.492

High

393688

EXD
Homeobox protein extradenticle

1

20

High-throughput

0.492

High

393698

SPT7
SAGA complex subunit Spt7

1

0

High-throughput

0.486

High

393700

Q9W3S4
LD46272p

1

0

High-throughput

0.486

High

121963

M9PH39
histone acetyltransferase

1

20

Small-scale

0.479

High

305451

O77430
GEO01111p1

1

2

High-throughput

0.479

High

393692

CLASP
CLIP-associating protein

1

2

High-throughput

0.479

High

393695

Q9VDE3
LD08669p

1

8

High-throughput

0.479

High

393699

Q9VYH9
Hector, isoform A

1

1

High-throughput

0.464

High

95197

E1JIH4
Uncharacterized protein, isoform D

1

0

High-throughput

0.458

High

393685

OSKA
Maternal effect protein oskar

2

0

High-throughput

0.310

High

393683

ARRA
Phosrestin-2

1

0

High-throughput

0.265

Low

393686

CAND
Calpain-D

1

0

High-throughput

0.265

Low

393690

Q7JZ94
Cuticular protein 50Ca

1

0

High-throughput

0.265

Low

393697

Q9VR24
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

393693

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025