Protein: RYR2
Ryanodine receptor 2 (RYR-2) (RyR2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)

Gene: RYR2
Organism: Mus musculus
Interactions: 68
UniProt ID: E9Q401

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0002027 - regulation of heart rate
GO:0003143 - embryonic heart tube morphogenesis
GO:0003220 - left ventricular cardiac muscle tissue morphogenesis
GO:0003300 - cardiac muscle hypertrophy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

93493

FKB1B
Peptidyl-prolyl cis-trans isomerase FKBP1B

2

10

Small-scale

0.776

High

93431

RYR2
Ryanodine receptor 2

2

16

Small-scale

0.744

High

93458

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

2

10

Small-scale

0.737

High

93470

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

2

11

Small-scale

0.737

High

93435

PKD2
Polycystin-2

1

20

Small-scale

0.618

High

93469

SORCN
Sorcin

1

7

Small-scale

0.618

High

93215

E9PV66
Myosin XVIIIb

1

8

High-throughput

0.575

High

93337

RYR1
Ryanodine receptor 1

1

17

High-throughput

0.575

High

93463

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

8

High-throughput

0.575

High

93464

MYH1
Myosin-1

1

11

High-throughput

0.575

High

93490

PLEC
Plectin

1

9

High-throughput

0.575

High

93252

E9PX29
Spectrin beta chain

1

7

High-throughput

0.514

High

93468

SPEG
Striated muscle-specific serine/threonine-protein kinase

1

13

High-throughput

0.514

High

93471

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

High-throughput

0.514

High

93474

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

5

High-throughput

0.514

High

93479

PLCE1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

1

6

Small-scale

0.500

High

93432

E9Q9K8
A kinase

1

9

Small-scale

0.479

High

93442

GRIA2
Glutamate receptor 2

1

6

High-throughput

0.479

High

93466

PSN2
Presenilin-2

1

1

Small-scale

0.479

High

93445

DYN2
Dynamin-2

1

1

High-throughput

0.457

High

93459

TERA
Transitional endoplasmic reticulum ATPase

1

6

High-throughput

0.457

High

93438

MYPC3
Myosin-binding protein C, cardiac-type

1

10

High-throughput

0.445

High

93439

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.445

High

93448

CAV3
Caveolin-3

1

3

High-throughput

0.445

High

93451

1433Z
14-3-3 protein zeta/delta

1

14

High-throughput

0.445

High

93454

ARF1
ADP-ribosylation factor 1

1

2

High-throughput

0.445

High

93461

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

2

High-throughput

0.445

High

93465

IRAG2
Inositol 1,4,5-triphosphate receptor associated 2

1

3

High-throughput

0.445

High

93467

SNTA1
Alpha-1-syntrophin

1

2

High-throughput

0.445

High

93477

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

8

High-throughput

0.445

High

93478

LRC10
Leucine-rich repeat-containing protein 10

1

5

High-throughput

0.445

High

93488

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

6

High-throughput

0.445

High

93075

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

8

High-throughput

0.407

High

93433

KNG1
Kininogen-1 [Cleaved into: Kininogen-1 heavy chain; Bradykinin; Kininogen-1 light chain]

1

5

High-throughput

0.407

High

93434

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.407

High

93437

PSA3
Proteasome subunit alpha type-3

1

3

High-throughput

0.407

High

93440

FABPH
Fatty acid-binding protein, heart

1

2

High-throughput

0.407

High

93441

CATD
Cathepsin D

1

1

High-throughput

0.407

High

93446

AINX
Alpha-internexin

1

8

High-throughput

0.407

High

93447

PSA2
Proteasome subunit alpha type-2

1

3

High-throughput

0.407

High

93449

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

4

High-throughput

0.407

High

93452

TCPB
T-complex protein 1 subunit beta

1

3

High-throughput

0.407

High

93453

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.407

High

93455

RL19
Large ribosomal subunit protein eL19

1

3

High-throughput

0.407

High

93456

H33
Histone H3.3

1

4

High-throughput

0.407

High

93457

G3BP2
Ras GTPase-activating protein-binding protein 2

1

6

High-throughput

0.407

High

93460

C1QC
Complement C1q subcomponent subunit C

1

1

High-throughput

0.407

High

93462

COBL1
Cordon-bleu protein-like 1

1

6

High-throughput

0.407

High

93472

TBB2A
Tubulin beta-2A chain

1

2

High-throughput

0.407

High

93475

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

1

4

High-throughput

0.407

High

93476

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

4

High-throughput

0.407

High

93480

FIBG
Fibrinogen gamma chain

1

8

High-throughput

0.407

High

93481

SFPQ
Splicing factor, proline- and glutamine-rich

1

8

High-throughput

0.407

High

93482

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

9

High-throughput

0.407

High

93483

SPA3N
Serine protease inhibitor A3N

1

5

High-throughput

0.407

High

93484

NONO
Non-POU domain-containing octamer-binding protein

1

9

High-throughput

0.407

High

93486

EF1G
Elongation factor 1-gamma

1

4

High-throughput

0.407

High

93487

HRG
Histidine-rich glycoprotein

1

4

High-throughput

0.407

High

93491

PSA4
Proteasome subunit alpha type-4

1

3

High-throughput

0.407

High

93492

SYVC
Valine--tRNA ligase

1

4

High-throughput

0.407

High

93489

COPB
Coatomer subunit beta

1

0

High-throughput

0.238

Low

93436

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.232

Low

93443

CTNA1
Catenin alpha-1

1

0

High-throughput

0.232

Low

93444

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.232

Low

93450

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.232

Low

93473

SPAT7
Spermatogenesis-associated protein 7 homolog

1

0

High-throughput

0.232

Low

93485

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024