HitPredict
Protein: PSN2
Presenilin-2 (PS-2) (EC 3.4.23.-) [Cleaved into: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit]

Gene: PSN2, Psen2
Organism: Mus musculus
Interactions: 11
UniProt ID: Q61144

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000139 - Golgi membrane
GO:0001708 - cell fate specification
GO:0001756 - somitogenesis
GO:0001921 - positive regulation of receptor recycling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

890094

 PSN1
Presenilin-1

1

7

Small-scale

 0.618

High

1222351

 APH1A
Gamma-secretase subunit APH-1A

1

10

Small-scale

 0.618

High

1222352

 PEN2
Gamma-secretase subunit PEN-2

1

7

Small-scale

 0.618

High

97965

 RYR2
Ryanodine receptor 2

1

1

Small-scale

 0.479

High

204906

 NOTC2
Neurogenic locus notch homolog protein 2

1

10

Small-scale

 0.479

High

728039

 NOTC4
Neurogenic locus notch homolog protein 4

1

11

Small-scale

 0.479

High

944777

 NICA
Nicastrin

1

6

Small-scale

 0.479

High

1032082

 NOTC1
Neurogenic locus notch homolog protein 1

1

11

Small-scale

 0.479

High

1222349

 NOTC3
Neurogenic locus notch homolog protein 3

1

11

Small-scale

 0.479

High

1222350

 SORCN
Sorcin

1

2

Small-scale

 0.479

High

1222353

 CSEN
Calsenilin

1

4

Small-scale

 0.479

High

Service provided by Combinatics, Japan

Last updated: 11Aug2025