Protein: APH1A
Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha)

Gene: APH1A
Organism: Mus musculus
Interactions: 15
UniProt ID: Q8BVF7

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001656 - metanephros development
GO:0005769 - early endosome
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

890097

PSN1
Presenilin-1

2

10

Small-scale

0.776

High

1222351

PSN2
Presenilin-2

1

10

Small-scale

0.618

High

944779

NICA
Nicastrin

1

6

Small-scale

0.515

High

147544

DPYL2
Dihydropyrimidinase-related protein 2

1

1

Small-scale

0.479

High

147971

STXB1
Syntaxin-binding protein 1

1

1

Small-scale

0.479

High

408255

MBP
Myelin basic protein

1

1

Small-scale

0.479

High

569652

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

1

Small-scale

0.479

High

949315

MYPR
Myelin proteolipid protein

1

1

Small-scale

0.479

High

972268

1433E
14-3-3 protein epsilon

1

1

Small-scale

0.479

High

983638

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

1

Small-scale

0.479

High

1244696

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

3

Small-scale

0.479

High

1297460

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

3

Small-scale

0.479

High

990009

1433Z
14-3-3 protein zeta/delta

1

3

Small-scale

0.437

High

1297459

PDE10
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

1

1

Small-scale

0.437

High

855300

SYT1
Synaptotagmin-1

1

0

Small-scale

0.426

High


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Last updated: 11Aug2025