Protein: RPA12
DNA-directed RNA polymerase I subunit RPA12 (A12) (A12.2) (DNA-directed RNA polymerase I 13.7 kDa polypeptide)

Gene: RPA12
Organism: Saccharomyces cerevisiae S288C
Interactions: 77
UniProt ID: P32529

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001054 - RNA polymerase I activity
GO:0003676 - nucleic acid binding
GO:0005634 - nucleus
GO:0005736 - RNA polymerase I complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

604521

RPA2
DNA-directed RNA polymerase I subunit RPA135

9

13

Small-scale

0.972

High

501339

RPA1
DNA-directed RNA polymerase I subunit RPA190

8

20

Small-scale

0.963

High

593120

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

4

6

High-throughput

0.896

High

692700

RPA49
DNA-directed RNA polymerase I subunit RPA49

3

3

Small-scale

0.830

High

692688

RPA43
DNA-directed RNA polymerase I subunit RPA43

5

1

Small-scale

0.714

High

429665

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

4

12

High-throughput

0.694

High

593215

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

4

7

High-throughput

0.694

High

604663

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

4

6

High-throughput

0.694

High

692699

CDC14
Tyrosine-protein phosphatase CDC14

4

1

High-throughput

0.691

High

593295

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

3

5

High-throughput

0.662

High

655595

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

3

9

High-throughput

0.662

High

692694

RPA14
DNA-directed RNA polymerase I subunit RPA14

4

0

Small-scale

0.650

High

692689

RPA34
DNA-directed RNA polymerase I subunit RPA34

3

0

Small-scale

0.616

High

692675

MSN4
Zinc finger protein MSN4

1

1

Small-scale

0.573

High

510640

SSB1
Ribosome-associated molecular chaperone SSB1

2

5

High-throughput

0.552

High

692682

SSB2
Ribosome-associated molecular chaperone SSB2

2

5

High-throughput

0.552

High

692702

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

692678

HMT1
Protein arginine N-methyltransferase 1

1

0

Small-scale

0.518

High

614905

KC12
Casein kinase I homolog 2

1

1

High-throughput

0.501

High

692697

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.489

High

416207

SIR2
NAD-dependent histone deacetylase SIR2

1

1

High-throughput

0.479

High

661660

TF2B
Transcription initiation factor IIB

1

6

High-throughput

0.479

High

692677

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.479

High

692683

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

5

High-throughput

0.479

High

692698

APJ1
J domain-containing protein APJ1

1

4

High-throughput

0.479

High

692706

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.479

High

692709

IWR1
RNA polymerase II nuclear localization protein IWR1

1

1

High-throughput

0.479

High

692684

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.460

High

692705

RNT1
Ribonuclease 3

1

0

Small-scale

0.460

High

406893

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

419461

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

645329

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

692679

RRN10
RNA polymerase I-specific transcription initiation factor RRN10

1

0

High-throughput

0.458

High

692685

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

692691

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

692696

RRN9
RNA polymerase I-specific transcription initiation factor RRN9

1

0

High-throughput

0.458

High

692711

MAK21
Ribosome biogenesis protein MAK21

1

0

High-throughput

0.458

High

490661

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.445

High

493475

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

413385

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

543405

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.437

High

692687

BUD27
Bud site selection protein 27

1

1

High-throughput

0.437

High

692690

NET1
Nucleolar protein NET1

1

1

High-throughput

0.437

High

692695

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.437

High

692704

TOF2
Topoisomerase 1-associated factor 2

1

1

High-throughput

0.437

High

376691

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.426

High

640881

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

692473

ZUO1
Zuotin

1

1

High-throughput

0.407

High

692673

RSSA1
Small ribosomal subunit protein uS2A

2

0

High-throughput

0.298

High

692680

RCK2
Serine/threonine-protein kinase RCK2

1

0

High-throughput

0.261

Low

692701

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.261

Low

141225

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

357952

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

383021

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

405504

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

407805

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

425832

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

470936

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

472088

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

479992

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

480555

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

482151

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

631747

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

634529

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

692674

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

692676

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

692681

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

692686

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

692692

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

692703

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

692707

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.249

Low

692708

VAM6
Vacuolar morphogenesis protein 6

1

0

Small-scale

0.249

Low

692710

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

399376

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

534716

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.232

Low

667137

RL8B
Large ribosomal subunit protein eL8B

1

0

High-throughput

0.232

Low

692693

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024