Protein: OTUB1
Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (Ubiquitin-specific-processing protease OTUB1)

Gene: OTUB1
Organism: Mus musculus
Interactions: 18
UniProt ID: Q7TQI3

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005737 - cytoplasm
GO:0006281 - DNA repair
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

509130

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

2

5

Small-scale

0.687

High

957885

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

11

Small-scale

0.618

High

670126

NECD
Necdin

1

2

Small-scale

0.481

High

530849

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.479

High

927859

ATX1
Ataxin-1

1

1

High-throughput

0.479

High

1191096

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

2

High-throughput

0.479

High

1224188

SMAD2
Mothers against decapentaplegic homolog 2

1

5

Small-scale

0.479

High

1274586

SMAD3
Mothers against decapentaplegic homolog 3

1

5

Small-scale

0.479

High

205061

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

0

High-throughput

0.458

High

915320

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

0

High-throughput

0.458

High

1274584

FACD2
Fanconi anemia group D2 protein homolog

1

0

High-throughput

0.458

High

999113

1433F
14-3-3 protein eta

1

5

High-throughput

0.445

High

1274585

WDTC1
WD and tetratricopeptide repeats protein 1

1

2

High-throughput

0.437

High

1274587

EED
Polycomb protein EED

1

1

High-throughput

0.437

High

1274588

ATAD1
Outer mitochondrial transmembrane helix translocase

1

1

Small-scale

0.437

High

1223585

DLG4
Disks large homolog 4

1

0

High-throughput

0.426

High

551451

A4
Amyloid-beta precursor protein

1

2

Small-scale

0.408

High

108733

G3X9H5
Huntingtin

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025