Protein: MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)

Gene: MCCA, Mccc1
Organism: Mus musculus
Interactions: 18
UniProt ID: Q99MR8

Gene Ontology (top 5):
GO:0004485 - methylcrotonoyl-CoA carboxylase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1408887

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

3

15

High-throughput

0.827

High

237047

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

3

High-throughput

0.479

High

1297430

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

1

0

High-throughput

0.458

High

267107

MYPC3
Myosin-binding protein C, cardiac-type

1

2

High-throughput

0.445

High

108836

G3X9H5
Huntingtin

1

2

High-throughput

0.437

High

398928

CFAD
Complement factor D

1

5

High-throughput

0.437

High

1188909

STING
Stimulator of interferon genes protein

1

2

High-throughput

0.437

High

1221812

SC6A4
Sodium-dependent serotonin transporter

1

1

High-throughput

0.437

High

1317615

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.437

High

1408888

HSPB2
Heat shock protein beta-2

1

2

High-throughput

0.437

High

267073

OSMR
Oncostatin-M-specific receptor subunit beta

1

4

Small-scale

0.407

High

651567

CBL
E3 ubiquitin-protein ligase CBL

1

9

High-throughput

0.407

High

1189591

CBLB
E3 ubiquitin-protein ligase CBL-B

1

4

High-throughput

0.407

High

1231068

Q6AXH7
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.407

High

1296736

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

3

High-throughput

0.407

High

1282445

FACD2
Fanconi anemia group D2 protein homolog

1

0

High-throughput

0.249

Low

905938

CAV3
Caveolin-3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025