Interactor 1: MCCA (Q99MR8)
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)
Gene: Mccc1

Interactor 2: MCCA (Q99MR8)
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha)
Gene: Mccc1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 29199018, 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Biotin_carb_C~Biotin_carb_C, Biotin_carb_C~Biotin_carb_N, Biotin_carb_C~Biotin_lipoyl, Biotin_carb_C~CPSase_L_D2, Biotin_carb_N~Biotin_carb_N, Biotin_carb_N~Biotin_lipoyl, Biotin_carb_N~CPSase_L_D2, Biotin_lipoyl~Biotin_lipoyl, Biotin_lipoyl~CPSase_L_D2, CPSase_L_D2~CPSase_L_D2
Common GO terms GO:0004485 - methylcrotonoyl-CoA carboxylase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005759 - mitochondrial matrix
and 3 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 717
Mm

1 717
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Cj
+ Ec
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025