Protein: SFPQ
Splicing factor, proline- and glutamine-rich (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)

Gene: SFPQ
Organism: Mus musculus
Interactions: 43
UniProt ID: Q8VIJ6

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000380 - alternative mRNA splicing, via spliceosome
GO:0000724 - double-strand break repair via homologous recombination
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1341536

PSPC1
Paraspeckle component 1

1

15

Small-scale

0.618

High

1354141

SFPQ
Splicing factor, proline- and glutamine-rich

1

17

High-throughput

0.618

High

1354143

TADBP
TAR DNA-binding protein 43

1

18

Small-scale

0.618

High

1354144

NONO
Non-POU domain-containing octamer-binding protein

1

18

Small-scale

0.618

High

312707

LMX1B
LIM homeobox transcription factor 1-beta

1

4

Small-scale

0.536

High

1354145

TSC1
Hamartin

1

14

High-throughput

0.536

High

205753

PER1
Period circadian protein homolog 1

1

7

Small-scale

0.479

High

236760

PER2
Period circadian protein homolog 2

1

7

Small-scale

0.479

High

542877

RARA
Retinoic acid receptor alpha

1

20

Small-scale

0.479

High

927947

ATX1
Ataxin-1

1

2

High-throughput

0.479

High

966060

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

20

High-throughput

0.479

High

972295

1433E
14-3-3 protein epsilon

1

6

High-throughput

0.479

High

990030

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1054422

NR4A2
Nuclear receptor subfamily 4 group A member 2

1

20

Small-scale

0.479

High

1189466

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

18

Small-scale

0.479

High

1191151

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

7

High-throughput

0.479

High

1221136

SIN3A
Paired amphipathic helix protein Sin3a

1

2

Small-scale

0.479

High

1222500

SAP
Prosaposin

1

1

High-throughput

0.479

High

1223454

CTR9
RNA polymerase-associated protein CTR9 homolog

1

9

Small-scale

0.479

High

1225212

TFE3
Transcription factor E3

1

8

High-throughput

0.479

High

1231594

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

18

Small-scale

0.479

High

1233048

TEDC2
Tubulin epsilon and delta complex protein 2

1

1

High-throughput

0.479

High

1257406

SPOP
Speckle-type POZ protein

1

6

High-throughput

0.479

High

1282334

FACD2
Fanconi anemia group D2 protein homolog

1

7

High-throughput

0.479

High

1298632

KAT5
Histone acetyltransferase KAT5

1

5

Small-scale

0.479

High

1317307

PPHLN
Periphilin-1

1

2

Small-scale

0.479

High

1354142

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

663161

GRIA2
Glutamate receptor 2

1

0

High-throughput

0.458

High

1297098

CBAR1
CBY1-interacting BAR domain-containing protein 1

1

0

High-throughput

0.458

High

236626

ITB3
Integrin beta-3

1

1

High-throughput

0.457

High

396

AUTS2
Autism susceptibility gene 2 protein homolog

1

9

Small-scale

0.445

High

98074

DESP
Desmoplakin

1

4

High-throughput

0.445

High

1354146

MECP2
Methyl-CpG-binding protein 2

1

9

Small-scale

0.445

High

398816

CFAD
Complement factor D

1

4

High-throughput

0.437

High

1296172

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

9

High-throughput

0.437

High

1298311

MT21E
Protein-lysine methyltransferase METTL21E

1

8

High-throughput

0.437

High

1298690

TTC23
Tetratricopeptide repeat protein 23

1

1

High-throughput

0.437

High

1317503

FNDC5
Fibronectin type III domain-containing protein 5

1

3

High-throughput

0.437

High

1341431

BFAR
Bifunctional apoptosis regulator

1

20

Small-scale

0.437

High

1353902

Q8VD35
Orthodenticle homeobox 2

1

5

Small-scale

0.437

High

97980

RYR2
Ryanodine receptor 2

1

8

High-throughput

0.407

High

1253438

Q6ZQ47
Activity-dependent neuroprotector homeobox protein

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025