Protein: UHRF2
E3 ubiquitin-protein ligase UHRF2 (EC 2.3.2.27) (NIRF) (Np95-like ring finger protein) (Nuclear protein 97) (Nuclear zinc finger protein Np97) (RING-type E3 ubiquitin transferase UHRF2) (Ubiquitin-like PHD and RING finger domain-containing protein 2) (Ubiquitin-like-containing PHD and RING finger domains protein 2)

Gene: UHRF2
Organism: Mus musculus
Interactions: 75
UniProt ID: Q7TMI3

Gene Ontology (top 5):
GO:0000792 - heterochromatin
GO:0003677 - DNA binding
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1274286

BAZ1B
Tyrosine-protein kinase BAZ1B

1

20

Small-scale

0.665

High

73917

B2RQG2
PHD finger protein 3

1

6

Small-scale

0.618

High

98168

E9Q6A7
Bromodomain PHD finger transcription factor

1

20

Small-scale

0.618

High

107149

F8VQ93
PH-interacting protein

1

20

Small-scale

0.618

High

312614

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

20

Small-scale

0.618

High

480978

NUCL
Nucleolin

1

9

Small-scale

0.618

High

508941

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

10

Small-scale

0.618

High

533442

H2B1F
Histone H2B type 1-F/J/L

1

20

Small-scale

0.618

High

533453

H2B1M
Histone H2B type 1-M

1

20

Small-scale

0.618

High

694443

H2AX
Histone H2AX

1

20

Small-scale

0.618

High

721341

CBX2
Chromobox protein homolog 2

1

20

Small-scale

0.618

High

936634

KMT2A
Histone-lysine N-methyltransferase 2A

1

20

Small-scale

0.618

High

1204122

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

9

Small-scale

0.618

High

1224053

TIF1B
Transcription intermediary factor 1-beta

1

20

Small-scale

0.618

High

1233104

H2A2A
Histone H2A type 2-A

1

20

Small-scale

0.618

High

1274261

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

15

Small-scale

0.618

High

1274269

NSD2
Histone-lysine N-methyltransferase NSD2

1

19

Small-scale

0.618

High

1274270

H2A1F
Histone H2A type 1-F

1

20

Small-scale

0.618

High

1274277

BRWD1
Bromodomain and WD repeat-containing protein 1

1

20

Small-scale

0.618

High

1274279

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

20

Small-scale

0.618

High

1274283

RBP2
E3 SUMO-protein ligase RanBP2

1

2

Small-scale

0.618

High

1274281

INT12
Integrator complex subunit 12

1

0

Small-scale

0.586

High

1274265

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

19

Small-scale

0.553

High

1274282

Q9DCC5
Cbx3 protein

1

20

Small-scale

0.553

High

1274287

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

4

Small-scale

0.553

High

1274276

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

17

Small-scale

0.515

High

59710

TPX2
Targeting protein for Xklp2

1

2

Small-scale

0.479

High

98298

E9QAR4
Zinc finger protein 384

1

2

Small-scale

0.479

High

109289

G5E8K8
AHNAK nucleoprotein

1

2

Small-scale

0.479

High

312027

WIZ
Protein Wiz

1

3

Small-scale

0.479

High

382497

P53
Cellular tumor antigen p53

1

7

Small-scale

0.479

High

482136

JUNB
Transcription factor JunB

1

4

Small-scale

0.479

High

688477

TWST1
Twist-related protein 1

1

6

High-throughput

0.479

High

964531

SUMO2
Small ubiquitin-related modifier 2

1

7

Small-scale

0.479

High

980655

H4
Histone H4

1

9

Small-scale

0.479

High

989262

HSP7C
Heat shock cognate 71 kDa protein

1

6

Small-scale

0.479

High

1023475

TBB5
Tubulin beta-5 chain

1

7

Small-scale

0.479

High

1030122

TOP2A
DNA topoisomerase 2-alpha

1

11

Small-scale

0.479

High

1201209

TR150
Thyroid hormone receptor-associated protein 3

1

12

Small-scale

0.479

High

1204087

TASO2
Protein TASOR 2

1

1

Small-scale

0.479

High

1221604

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

3

Small-scale

0.479

High

1222193

LAP2B
Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma

1

2

Small-scale

0.479

High

1222458

HCFC1
Host cell factor 1

1

4

Small-scale

0.479

High

1222763

ZN638
Zinc finger protein 638

1

5

Small-scale

0.479

High

1223250

ATRX
Transcriptional regulator ATRX

1

17

Small-scale

0.479

High

1223411

NPM
Nucleophosmin

1

4

Small-scale

0.479

High

1225762

TOP2B
DNA topoisomerase 2-beta

1

12

Small-scale

0.479

High

1235703

NIPBL
Nipped-B-like protein

1

13

Small-scale

0.479

High

1239845

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

1

Small-scale

0.479

High

1246052

RIF1
Telomere-associated protein RIF1

1

11

Small-scale

0.479

High

1253435

Q6ZQ47
Activity-dependent neuroprotector homeobox protein

1

6

Small-scale

0.479

High

1274262

MBB1A
Myb-binding protein 1A

1

3

Small-scale

0.479

High

1274264

KI20B
Kinesin-like protein KIF20B

1

13

Small-scale

0.479

High

1274267

KAISO
Transcriptional regulator Kaiso

1

3

Small-scale

0.479

High

1274268

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

7

Small-scale

0.479

High

1274272

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

8

Small-scale

0.479

High

1274273

VIGLN
Vigilin

1

13

Small-scale

0.479

High

1274275

TAF9
Transcription initiation factor TFIID subunit 9

1

1

Small-scale

0.479

High

1274280

SERB1
SERPINE1 mRNA-binding protein 1

1

7

Small-scale

0.479

High

1274284

DDX21
Nucleolar RNA helicase 2

1

15

Small-scale

0.479

High

1274285

SUMO3
Small ubiquitin-related modifier 3

1

7

Small-scale

0.479

High

1190833

PEG3
Paternally-expressed gene 3 protein

1

0

Small-scale

0.458

High

1242724

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

0

Small-scale

0.458

High

1274263

SGO2A
Shugoshin 2A

1

0

Small-scale

0.458

High

1274274

STEEP
STING ER exit protein

1

0

Small-scale

0.458

High

59869

MGAP
MAX gene-associated protein

1

7

Small-scale

0.437

High

104753

TPR
Nucleoprotein TPR

1

9

Small-scale

0.437

High

609024

HS71B
Heat shock 70 kDa protein 1B

1

6

Small-scale

0.437

High

628509

VIME
Vimentin

1

20

Small-scale

0.437

High

1222227

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

5

Small-scale

0.437

High

1225293

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

4

Small-scale

0.437

High

1274266

Q8BH76
DNA polymerase delta subunit 3

1

1

Small-scale

0.437

High

1274271

NAT10
RNA cytidine acetyltransferase

1

3

Small-scale

0.437

High

1274278

SMTN
Smoothelin

1

3

Small-scale

0.437

High


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Last updated: 11Aug2025