Protein: ATN1
Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein)

Gene: ATN1
Organism: Homo sapiens
Interactions: 183
UniProt ID: P54259

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001906 - cell killing
GO:0003713 - transcription coactivator activity
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

869446

WDR5
WD repeat-containing protein 5

6

9

High-throughput

0.740

High

869459

MTG8
Protein CBFA2T1

3

6

Small-scale

0.671

High

869551

RERE
Arginine-glutamic acid dipeptide repeats protein

3

15

Small-scale

0.653

High

869559

BAIP2
BAR/IMD domain-containing adapter protein 2

2

8

Small-scale

0.653

High

125277

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

9

Small-scale

0.629

High

869454

EWS
RNA-binding protein EWS

2

6

High-throughput

0.614

High

869515

LENG8
Leukocyte receptor cluster member 8

2

8

High-throughput

0.613

High

869491

SIAH1
E3 ubiquitin-protein ligase SIAH1

2

4

High-throughput

0.595

High

869535

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

2

9

Small-scale

0.595

High

808424

YAP1
Transcriptional coactivator YAP1

2

20

High-throughput

0.595

High

869553

ZN608
Zinc finger protein 608

2

9

Small-scale

0.595

High

869563

NR2E1
Nuclear receptor subfamily 2 group E member 1

2

20

Small-scale

0.594

High

869547

RFOX1
RNA binding protein fox-1 homolog 1

1

5

High-throughput

0.573

High

869469

TRIP6
Thyroid receptor-interacting protein 6

1

0

High-throughput

0.558

High

869526

RHXF2
Rhox homeobox family member 2

1

13

High-throughput

0.552

High

170053

PLS1
Phospholipid scramblase 1

1

2

High-throughput

0.541

High

209017

NCK2
Cytoplasmic protein NCK2

1

15

High-throughput

0.541

High

843584

FXR1
RNA-binding protein FXR1

1

9

High-throughput

0.541

High

843992

FXR2
RNA-binding protein FXR2

1

9

High-throughput

0.541

High

869445

PSME3
Proteasome activator complex subunit 3

1

2

High-throughput

0.541

High

869500

TSC1
Hamartin

1

3

High-throughput

0.541

High

869527

EFC4B
EF-hand calcium-binding domain-containing protein 4B

1

1

High-throughput

0.541

High

869466

RBBP5
Retinoblastoma-binding protein 5

1

17

High-throughput

0.536

High

869498

AUTS2
Autism susceptibility gene 2 protein

1

18

Small-scale

0.536

High

869490

MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

1

15

Small-scale

0.527

High

869511

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

9

Small-scale

0.527

High

869516

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

12

Small-scale

0.527

High

869504

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.518

High

869521

MDFI
MyoD family inhibitor

1

0

High-throughput

0.518

High

869464

BECN1
Beclin-1

1

0

Small-scale

0.513

High

150922

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

9

High-throughput

0.508

High

198865

RFOX2
RNA binding protein fox-1 homolog 2

1

6

High-throughput

0.508

High

199101

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

5

High-throughput

0.508

High

203444

MTG8R
Protein CBFA2T2

1

4

High-throughput

0.508

High

637819

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.508

High

803452

BAG6
Large proline-rich protein BAG6

1

10

High-throughput

0.508

High

820857

PRC2A
Protein PRRC2A

1

17

High-throughput

0.508

High

869438

ATN1
Atrophin-1

1

12

High-throughput

0.508

High

869453

RBM10
RNA-binding protein 10

1

2

High-throughput

0.508

High

869460

TLE5
TLE family member 5

1

4

High-throughput

0.508

High

869471

MA7D1
MAP7 domain-containing protein 1

1

5

High-throughput

0.508

High

869488

MEGF8
Multiple epidermal growth factor-like domains protein 8

1

16

High-throughput

0.508

High

869489

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

High-throughput

0.508

High

869499

KAT6B
Histone acetyltransferase KAT6B

1

15

High-throughput

0.508

High

869501

KAT6A
Histone acetyltransferase KAT6A

1

14

High-throughput

0.508

High

869503

NELL1
Protein kinase C-binding protein NELL1

1

11

High-throughput

0.508

High

869517

SPAG5
Sperm-associated antigen 5

1

3

High-throughput

0.508

High

869518

NELL2
Protein kinase C-binding protein NELL2

1

15

High-throughput

0.508

High

869522

TEP1
Telomerase protein component 1

1

10

High-throughput

0.508

High

869555

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

11

High-throughput

0.508

High

869560

JAG2
Protein jagged-2

1

5

High-throughput

0.508

High

869564

ARIP4
Helicase ARIP4

1

4

High-throughput

0.508

High

869541

PKHA5
Pleckstrin homology domain-containing family A member 5

1

14

High-throughput

0.506

High

869505

GCC1
GRIP and coiled-coil domain-containing protein 1

1

3

High-throughput

0.494

High

869524

KR412
Keratin-associated protein 4-12

1

7

High-throughput

0.494

High

869533

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

10

High-throughput

0.494

High

839470

SPB8
Serpin B8

1

0

High-throughput

0.493

High

362074

MBP
Myelin basic protein

1

0

High-throughput

0.486

High

869444

ARF3
ADP-ribosylation factor 3

1

0

High-throughput

0.486

High

869452

LRP2
Low-density lipoprotein receptor-related protein 2

1

0

High-throughput

0.486

High

869513

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.486

High

869542

CENPJ
Centromere protein J

1

0

High-throughput

0.486

High

159935

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

4

High-throughput

0.481

High

257460

CREST
Calcium-responsive transactivator

1

5

High-throughput

0.481

High

271062

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

2

High-throughput

0.481

High

309681

KAT7
Histone acetyltransferase KAT7

1

7

High-throughput

0.481

High

312752

TFIP8
Tumor necrosis factor alpha-induced protein 8

1

1

High-throughput

0.481

High

324296

BAG3
BAG family molecular chaperone regulator 3

1

2

High-throughput

0.481

High

443419

VIME
Vimentin

1

6

High-throughput

0.481

High

855000

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

5

High-throughput

0.481

High

869447

CSK21
Casein kinase II subunit alpha

1

10

High-throughput

0.481

High

869449

PITX1
Pituitary homeobox 1

1

14

High-throughput

0.481

High

869457

TLE1
Transducin-like enhancer protein 1

1

12

High-throughput

0.481

High

869463

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

High-throughput

0.481

High

869482

OLIG3
Oligodendrocyte transcription factor 3

1

7

High-throughput

0.481

High

869486

SAXO4
Stabilizer of axonemal microtubules 4

1

1

High-throughput

0.481

High

869487

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

17

High-throughput

0.481

High

869510

ZN503
Zinc finger protein 503

1

1

High-throughput

0.481

High

869512

RBM14
RNA-binding protein 14

1

8

High-throughput

0.481

High

869519

PITX2
Pituitary homeobox 2

1

14

High-throughput

0.481

High

869523

RBM4B
RNA-binding protein 4B

1

7

High-throughput

0.481

High

869525

HINFP
Histone H4 transcription factor

1

3

Small-scale

0.481

High

869531

TEKT3
Tektin-3

1

1

High-throughput

0.481

High

869532

DGC6L
Protein DGCR6L

1

1

High-throughput

0.481

High

869544

DMRT3
Doublesex- and mab-3-related transcription factor 3

1

1

High-throughput

0.481

High

869546

EKI2
Ethanolamine kinase 2

1

1

High-throughput

0.481

High

869558

CTND2
Catenin delta-2

1

6

Small-scale

0.481

High

869562

NOC2L
Nucleolar complex protein 2 homolog

1

1

High-throughput

0.481

High

68279

P20L1
PHD finger protein 20-like protein 1

1

5

High-throughput

0.479

High

122583

MEN1
Menin

1

3

High-throughput

0.479

High

164205

ZN609
Zinc finger protein 609

1

13

High-throughput

0.479

High

165652

SET1A
Histone-lysine N-methyltransferase SETD1A

1

20

High-throughput

0.479

High

171012

TBXT
T-box transcription factor T

1

5

High-throughput

0.479

High

197683

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.479

High

267637

TADA3
Transcriptional adapter 3

1

1

High-throughput

0.479

High

318592

EYA4
Eyes absent homolog 4

1

14

High-throughput

0.479

High

487262

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

505199

EGR2
E3 SUMO-protein ligase EGR2

1

5

High-throughput

0.479

High

600108

TAF1
Transcription initiation factor TFIID subunit 1

1

13

High-throughput

0.479

High

679076

TLX1
T-cell leukemia homeobox protein 1

1

17

High-throughput

0.479

High

848177

HCFC1
Host cell factor 1

1

12

High-throughput

0.479

High

869439

TERF1
Telomeric repeat-binding factor 1

1

2

High-throughput

0.479

High

869440

FOXA1
Hepatocyte nuclear factor 3-alpha

1

5

High-throughput

0.479

High

869441

PAX9
Paired box protein Pax-9

1

14

High-throughput

0.479

High

869442

GSC
Homeobox protein goosecoid

1

12

High-throughput

0.479

High

869448

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

869456

KMT2A
Histone-lysine N-methyltransferase 2A

1

20

High-throughput

0.479

High

869458

TLE3
Transducin-like enhancer protein 3

1

12

High-throughput

0.479

High

869468

TERF2
Telomeric repeat-binding factor 2

1

2

High-throughput

0.479

High

869478

GGYF2
GRB10-interacting GYF protein 2

1

4

Small-scale

0.479

High

869483

KANL1
KAT8 regulatory NSL complex subunit 1

1

1

High-throughput

0.479

High

869484

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

869492

ZZZ3
ZZ-type zinc finger-containing protein 3

1

1

High-throughput

0.479

High

869494

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.479

High

869495

NUP43
Nucleoporin Nup43

1

16

High-throughput

0.479

High

869496

NUP35
Nucleoporin NUP35

1

2

High-throughput

0.479

High

869497

SP7
Transcription factor Sp7

1

9

High-throughput

0.479

High

869506

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

11

High-throughput

0.479

High

869508

SGF29
SAGA-associated factor 29

1

1

High-throughput

0.479

High

869509

MCRS1
Microspherule protein 1

1

1

High-throughput

0.479

High

869529

PHF20
PHD finger protein 20

1

8

High-throughput

0.479

High

869537

KAT8
Histone acetyltransferase KAT8

1

7

High-throughput

0.479

High

869538

CSR2B
Cysteine-rich protein 2-binding protein

1

9

High-throughput

0.479

High

869540

KANL2
KAT8 regulatory NSL complex subunit 2

1

1

High-throughput

0.479

High

869545

MBIP1
MAP3K12-binding inhibitory protein 1

1

1

High-throughput

0.479

High

869548

WWOX
WW domain-containing oxidoreductase

1

2

High-throughput

0.479

High

869549

CXXC1
CXXC-type zinc finger protein 1

1

15

High-throughput

0.479

High

869550

KANL3
KAT8 regulatory NSL complex subunit 3

1

2

High-throughput

0.479

High

869554

YETS2
YEATS domain-containing protein 2

1

11

High-throughput

0.479

High

869556

KMT2B
Histone-lysine N-methyltransferase 2B

1

20

High-throughput

0.479

High

869557

SET1B
Histone-lysine N-methyltransferase SETD1B

1

20

High-throughput

0.479

High

869561

KDM2A
Lysine-specific demethylase 2A

1

5

Small-scale

0.479

High

869566

HCFC2
Host cell factor 2

1

12

High-throughput

0.479

High

61627

MEG11
Multiple epidermal growth factor-like domains protein 11

1

4

High-throughput

0.464

High

129725

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

5

High-throughput

0.464

High

254210

SLIT1
Slit homolog 1 protein

1

2

High-throughput

0.464

High

254233

MEGF6
Multiple epidermal growth factor-like domains protein 6

1

7

High-throughput

0.464

High

264284

GGYF1
GRB10-interacting GYF protein 1

1

3

High-throughput

0.464

High

327971

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

11

High-throughput

0.464

High

612833

FBLN1
Fibulin-1

1

14

High-throughput

0.464

High

869450

FBLN2
Fibulin-2

1

15

High-throughput

0.464

High

869451

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

4

High-throughput

0.464

High

869455

CACB1
Voltage-dependent L-type calcium channel subunit beta-1

1

1

High-throughput

0.464

High

869461

DMPK
Myotonin-protein kinase

1

2

High-throughput

0.464

High

869462

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

1

13

High-throughput

0.464

High

869465

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

12

High-throughput

0.464

High

869467

K1H1
Keratin, type I cuticular Ha1

1

1

High-throughput

0.464

High

869470

ECM1
Extracellular matrix protein 1

1

1

High-throughput

0.464

High

869476

PRC2B
Protein PRRC2B

1

13

High-throughput

0.464

High

869480

STXB4
Syntaxin-binding protein 4

1

6

High-throughput

0.464

High

869481

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

1

5

High-throughput

0.464

High

869493

LTBP4
Latent-transforming growth factor beta-binding protein 4

1

9

High-throughput

0.464

High

869502

PCSK5
Proprotein convertase subtilisin/kexin type 5

1

5

High-throughput

0.464

High

869507

RNF31
E3 ubiquitin-protein ligase RNF31

1

4

High-throughput

0.464

High

869536

CHRD
Chordin

1

5

High-throughput

0.464

High

869543

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

9

High-throughput

0.464

High

869552

FBLN5
Fibulin-5

1

12

High-throughput

0.464

High

381882

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.460

High

869565

RN115
E3 ubiquitin-protein ligase RNF115

1

0

Small-scale

0.460

High

869530

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

230103

ZN862
Zinc finger protein 862

1

1

High-throughput

0.457

High

253969

MTG16
Protein CBFA2T3

1

4

Small-scale

0.457

High

260294

PROP1
Homeobox protein prophet of Pit-1

1

12

Small-scale

0.457

High

869539

Q9H9J5
cDNA FLJ12694 fis, clone NT2RP1000358, highly similar to Homo sapiens mRNA; cDNA DKFZp564C186

1

1

High-throughput

0.457

High

869514

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

6

High-throughput

0.445

High

58861

SSPO
SCO-spondin

1

5

High-throughput

0.439

High

150690

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

12

Small-scale

0.439

High

869443

KR122
Keratin-associated protein 12-2

1

6

High-throughput

0.439

High

869472

KR192
Keratin-associated protein 19-2

1

1

High-throughput

0.439

High

869473

KRA62
Keratin-associated protein 6-2

1

2

High-throughput

0.439

High

869474

KR195
Keratin-associated protein 19-5

1

1

High-throughput

0.439

High

869475

KR151
Keratin-associated protein 15-1

1

1

High-throughput

0.439

High

869479

S2548
Solute carrier family 25 member 48

1

1

High-throughput

0.439

High

869485

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

1

2

High-throughput

0.439

High

869520

LYST
Lysosomal-trafficking regulator

1

7

Small-scale

0.439

High

869534

KRA93
Keratin-associated protein 9-3

1

6

High-throughput

0.439

High

64526

ZSWM8
Zinc finger SWIM domain-containing protein 8

1

0

High-throughput

0.265

Low

571695

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

0

High-throughput

0.265

Low

660441

GRN
Progranulin

1

0

High-throughput

0.265

Low

857912

CRIP2
Cysteine-rich protein 2

1

0

High-throughput

0.265

Low

869528

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.249

Low

869477

Q5ZEY4
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024