Protein: ERG1
Squalene monooxygenase (EC 1.14.14.17) (Squalene epoxidase) (SE)

Gene: ERG1, SQLE
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q14534

Gene Ontology (top 5):
GO:0004506 - squalene monooxygenase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006696 - ergosterol biosynthetic process
GO:0008203 - cholesterol metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

231865

MARH6
E3 ubiquitin-protein ligase MARCHF6

5

1

Small-scale

0.707

High

1055238

FAF2
FAS-associated factor 2

3

0

High-throughput

0.638

High

134653

NPT3
Sodium-dependent phosphate transport protein 3

2

1

High-throughput

0.628

High

1055237

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

1

High-throughput

0.606

High

966807

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

0

High-throughput

0.602

High

1055232

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

2

0

High-throughput

0.602

High

1055236

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

0

High-throughput

0.602

High

1055246

REEP4
Receptor expression-enhancing protein 4

2

0

High-throughput

0.580

High

867971

VMAT1
Chromaffin granule amine transporter

1

1

High-throughput

0.536

High

1055244

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

1

High-throughput

0.536

High

196775

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.513

High

558726

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

0

High-throughput

0.513

High

919076

RAN
GTP-binding nuclear protein Ran

1

0

High-throughput

0.513

High

1053752

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.513

High

1055229

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1055240

RUSF1
RUS family member 1

1

0

High-throughput

0.513

High

1055241

ZDH12
Palmitoyltransferase ZDHHC12

1

0

High-throughput

0.513

High

1055235

OR6T1
Olfactory receptor 6T1

1

1

High-throughput

0.489

High

1055248

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

1

High-throughput

0.489

High

1055251

PCDGL
Protocadherin gamma-C4

1

1

High-throughput

0.489

High

1055252

PCDG5
Protocadherin gamma-A5

1

1

High-throughput

0.489

High

216724

CREB3
Cyclic AMP-responsive element-binding protein 3

1

1

High-throughput

0.481

High

1055230

RNFT1
E3 ubiquitin-protein ligase RNFT1

1

1

High-throughput

0.479

High

1055239

RN185
E3 ubiquitin-protein ligase RNF185

1

1

High-throughput

0.479

High

1055249

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1055250

AMFR
E3 ubiquitin-protein ligase AMFR

1

1

High-throughput

0.479

High

1055245

B2L13
Bcl-2-like protein 13

1

0

Small-scale

0.460

High

1055227

IRF4
Interferon regulatory factor 4

1

0

Small-scale

0.458

High

346782

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

940898

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

1055233

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

111537

SIM22
Small integral membrane protein 22

1

0

Small-scale

0.426

High

354948

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

0

High-throughput

0.426

High

989615

ACHD
Acetylcholine receptor subunit delta

2

0

High-throughput

0.328

High

1055228

S39AC
Zinc transporter ZIP12

2

0

High-throughput

0.328

High

1055231

TRML2
Trem-like transcript 2 protein

2

0

High-throughput

0.318

High

1055247

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

457149

ALDOC
Fructose-bisphosphate aldolase C

1

0

High-throughput

0.282

High

1055243

ZN641
Zinc finger protein 641

1

0

High-throughput

0.282

High

1055234

OR2M7
Olfactory receptor 2M7

1

0

High-throughput

0.279

Low

1055242

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.279

Low

1055253

PTC2
Protein patched homolog 2

1

0

High-throughput

0.279

Low

903225

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024