HitPredict

Interactor 1: NHR43 (Q18299)
Nuclear hormone receptor family member nhr-43
Gene: nhr-43

Interactor 2: Q86PI8 (Q86PI8)
Nuclear receptor NHR-114
Gene: Q86PI8

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Hormone_recep~Hormone_recep, Hormone_recep~zf-C4, zf-C4~zf-C4
Common GO terms	GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 449 Ce			1 304
+	Ce
		112628 NHR43_CAEEL (1-449): 7.25e-99: 305: 100.00		NH114_CAEEL (1-304): 1.45e-89: 274: 94.41
+	Ce
		1164724 NHR43_CAEEL (1-449): 7.25e-99: 305: 100.00		NHR47_CAEEL (5-271): 9.65e-70: 228: 32.48
+	Ce
		837123 NHR10_CAEEL (30-448): 1.19e-79: 254: 14.05		NHR10_CAEEL (2-304): 3.79e-74: 234: 52.48
+	Hs
		395475 RXRA_HUMAN (3-449): 1.49e-85: 271: 13.59		ESR1_HUMAN (7-303): 1.58e-63: 212: 23.00
+	Hs
		543559 RXRA_HUMAN (3-449): 1.49e-85: 271: 13.59		ERR1_HUMAN (8-281): 2.01e-61: 202: 24.45
+	Hs
		625807 RXRA_HUMAN (3-449): 1.49e-85: 271: 13.59		NR1H3_HUMAN (3-303): 4.42e-61: 202: 21.60
+	Mm
		704503 RXRA_MOUSE (3-449): 7.6e-86: 272: 13.38		NR1H3_MOUSE (3-303): 1.47e-60: 200: 21.60
+	Hs
		533245 RXRA_HUMAN (3-449): 1.49e-85: 271: 13.59		THA_HUMAN (1-283): 2.58e-59: 198: 20.00
+	Hs
		625788 RXRA_HUMAN (3-449): 1.49e-85: 271: 13.59		NR1H2_HUMAN (3-303): 2.34e-59: 198: 19.28
+	Hs
		565506 RXRA_HUMAN (3-449): 1.49e-85: 271: 13.59		RARG_HUMAN (13-284): 2.5e-59: 197: 23.53
+	Hs
		403810 RXRA_HUMAN (3-449): 1.49e-85: 271: 13.59		GCR_HUMAN (5-303): 6.89e-56: 194: 19.21
+	Hs
		625780 RXRA_HUMAN (3-449): 1.49e-85: 271: 13.59		RXRG_HUMAN (3-280): 2.78e-57: 192: 24.46
+	Ce
		233373 O44577_CAEEL (43-419): 1.33e-80: 257: 22.25		NHR49_CAEEL (13-282): 6.11e-62: 205: 27.78
+	Hs
		625756 RXRA_HUMAN (3-449): 1.49e-85: 271: 13.59		RXRA_HUMAN (3-287): 3.31e-56: 190: 22.11
+	Mm
		704571 RXRG_MOUSE (1-449): 3.21e-79: 254: 12.42		NR1H3_MOUSE (3-303): 1.47e-60: 200: 21.60
+	Mm
		704569 RXRG_MOUSE (1-449): 3.21e-79: 254: 12.42		NR1H2_MOUSE (3-303): 9.77e-60: 198: 18.81
+	Hs
		98533 RXRB_HUMAN (17-449): 7.38e-78: 253: 13.10		F1D8P7_HUMAN (3-303): 1.29e-57: 193: 19.22
+	Mm
		542829 RXRA_MOUSE (3-449): 7.6e-86: 272: 13.38		RARA_MOUSE (15-90): 4.62e-21: 94.7: 50.00
+	Hs
		520510 RXRA_HUMAN (3-449): 1.49e-85: 271: 13.59		RARA_HUMAN (15-90): 4.41e-21: 94.7: 50.00
+	Hs
		533212 RXRA_HUMAN (3-449): 1.49e-85: 271: 13.59		RARB_HUMAN (15-114): 8.33e-21: 94: 41.00