Protein: LNX1
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb protein X 1) (Ligand of Numb-binding protein 1) (Numb-binding protein 1) (RING-type E3 ubiquitin transferase LNX)

Gene: LNX1
Organism: Mus musculus
Interactions: 87
UniProt ID: O70263

Gene Ontology (top 5):
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination
GO:0030165 - PDZ domain binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

250665

NUMB
Protein numb homolog

1

20

Small-scale

0.724

High

400

A0A087WPM2
Protein tyrosine phosphatase, receptor type, f polypeptide

1

20

High-throughput

0.618

High

71321

B2RXW8
Ppfia1 protein

1

15

High-throughput

0.618

High

250592

LNX1
E3 ubiquitin-protein ligase LNX

1

19

Small-scale

0.618

High

250603

LIPA3
Liprin-alpha-3

1

15

High-throughput

0.618

High

250608

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

20

High-throughput

0.618

High

250640

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

15

High-throughput

0.618

High

250631

IGSF5
Immunoglobulin superfamily member 5

1

4

Small-scale

0.561

High

250623

KAZRN
Kazrin

1

14

High-throughput

0.553

High

250638

LIPA2
Liprin-alpha-2

1

20

High-throughput

0.553

High

250641

LIPB1
Liprin-beta-1

1

15

High-throughput

0.553

High

250597

CAH1
Carbonic anhydrase 1

1

5

Small-scale

0.552

High

250614

CXAR
Coxsackievirus and adenovirus receptor homolog

1

20

Small-scale

0.506

High

192816

CDK14
Cyclin-dependent kinase 14

1

4

High-throughput

0.479

High

193580

CTND2
Catenin delta-2

1

20

High-throughput

0.479

High

250595

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

3

High-throughput

0.479

High

250596

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

1

5

High-throughput

0.479

High

250598

HS71B
Heat shock 70 kDa protein 1B

1

8

High-throughput

0.479

High

250599

SC6A1
Sodium- and chloride-dependent GABA transporter 1

1

20

High-throughput

0.479

High

250601

HS74L
Heat shock 70 kDa protein 4L

1

8

High-throughput

0.479

High

250602

EAA1
Excitatory amino acid transporter 1

1

6

High-throughput

0.479

High

250604

1433G
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]

1

20

High-throughput

0.479

High

250605

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

2

High-throughput

0.479

High

250606

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

250607

KPCG
Protein kinase C gamma type

1

18

High-throughput

0.479

High

250609

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

250610

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.479

High

250615

CTNB1
Catenin beta-1

1

19

High-throughput

0.479

High

250619

CTNA2
Catenin alpha-2

1

6

High-throughput

0.479

High

250621

NDRG1
Protein NDRG1

1

2

High-throughput

0.479

High

250622

HECAM
Hepatic and glial cell adhesion molecule

1

19

High-throughput

0.479

High

250624

CARL1
F-actin-uncapping protein LRRC16A

1

1

High-throughput

0.479

High

250625

SPKAP
A-kinase anchor protein SPHKAP

1

2

High-throughput

0.479

High

250628

ERC2
ERC protein 2

1

15

High-throughput

0.479

High

250629

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

16

High-throughput

0.479

High

250633

C170B
Centrosomal protein of 170 kDa protein B

1

9

High-throughput

0.479

High

250637

ATLA1
Atlastin-1

1

1

High-throughput

0.479

High

250639

Q8C048
Calcium-transporting ATPase

1

15

High-throughput

0.479

High

250643

FERM2
Fermitin family homolog 2

1

2

High-throughput

0.479

High

250644

TBCE
Tubulin-specific chaperone E

1

5

High-throughput

0.479

High

250647

WASF1
Actin-binding protein WASF1

1

7

High-throughput

0.479

High

250648

MIOS
GATOR2 complex protein MIOS

1

1

High-throughput

0.479

High

250652

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

20

High-throughput

0.479

High

250653

SRGP1
SLIT-ROBO Rho GTPase-activating protein 1

1

20

High-throughput

0.479

High

250655

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

11

High-throughput

0.479

High

250656

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.479

High

250657

DTNA
Dystrobrevin alpha

1

7

High-throughput

0.479

High

250658

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed]

1

7

High-throughput

0.479

High

250661

SRCN1
SRC kinase signaling inhibitor 1

1

7

High-throughput

0.479

High

250663

NDRG3
Protein NDRG3

1

2

High-throughput

0.479

High

250664

NDRG2
Protein NDRG2

1

2

High-throughput

0.479

High

250667

AT12A
Potassium-transporting ATPase alpha chain 2

1

5

High-throughput

0.479

High

57129

CAMP1
Calmodulin-regulated spectrin-associated protein 1

1

0

High-throughput

0.458

High

250600

SYWC
Tryptophan--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

250659

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.458

High

69900

SCN7A
Sodium channel protein type 7 subunit alpha

1

4

Small-scale

0.457

High

82718

CTTB2
Cortactin-binding protein 2

1

10

High-throughput

0.437

High

193231

AP1B1
AP-1 complex subunit beta-1

1

4

High-throughput

0.437

High

193426

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

4

High-throughput

0.437

High

250593

CLD1
Claudin-1

1

7

Small-scale

0.437

High

250594

K1C13
Keratin, type I cytoskeletal 13

1

8

High-throughput

0.437

High

250611

LDB1
LIM domain-binding protein 1

1

1

High-throughput

0.437

High

250612

TCPB
T-complex protein 1 subunit beta

1

2

High-throughput

0.437

High

250613

NPTN
Neuroplastin

1

9

High-throughput

0.437

High

250616

Q3U2G2
Heat shock 70 kDa protein 4

1

8

High-throughput

0.437

High

250617

FCSD2
F-BAR and double SH3 domains protein 2

1

8

High-throughput

0.437

High

250618

2A5G
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

1

1

High-throughput

0.437

High

250620

K1C15
Keratin, type I cytoskeletal 15

1

9

High-throughput

0.437

High

250626

BCR
Breakpoint cluster region protein

1

20

High-throughput

0.437

High

250627

PHLB1
Pleckstrin homology-like domain family B member 1

1

20

High-throughput

0.437

High

250630

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

3

High-throughput

0.437

High

250635

GSTM7
Glutathione S-transferase Mu 7

1

2

High-throughput

0.437

High

250636

EFTU
Elongation factor Tu, mitochondrial

1

4

High-throughput

0.437

High

250642

KLH11
Kelch-like protein 11

1

10

High-throughput

0.437

High

250645

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

7

High-throughput

0.437

High

250649

Q91V89
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit

1

1

High-throughput

0.437

High

250650

Q91WH7
Sodium/potassium-transporting ATPase subunit alpha

1

5

High-throughput

0.437

High

250651

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.437

High

250654

VMA5A
von Willebrand factor A domain-containing protein 5A

1

1

High-throughput

0.437

High

250660

NDEL1
Nuclear distribution protein nudE-like 1

1

5

High-throughput

0.437

High

250662

ADDA
Alpha-adducin

1

5

High-throughput

0.437

High

250666

UN13B
Protein unc-13 homolog B

1

12

High-throughput

0.437

High

222966

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.249

Low

250632

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

250634

TCPR1
Tectonin beta-propeller repeat-containing protein 1

1

0

High-throughput

0.249

Low

250646

SNP47
Synaptosomal-associated protein 47

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024