Protein: TNF10
Tumor necrosis factor ligand superfamily member 10 (Apo-2 ligand) (Apo-2L) (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD antigen CD253)

Gene: TNF10, TNFSF10
Organism: Homo sapiens
Interactions: 38
UniProt ID: P50591

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005125 - cytokine activity
GO:0005164 - tumor necrosis factor receptor binding
GO:0005576 - extracellular region
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

154326

TR10B
Tumor necrosis factor receptor superfamily member 10B

19

20

Small-scale

0.985

High

121456

TR10A
Tumor necrosis factor receptor superfamily member 10A

5

20

Small-scale

0.908

High

841082

TR10D
Tumor necrosis factor receptor superfamily member 10D

3

20

Small-scale

0.845

High

841073

CASP8
Caspase-8

17

13

Small-scale

0.760

High

841068

FADD
FAS-associated death domain protein

16

16

Small-scale

0.759

High

181595

CFLAR
CASP8 and FADD-like apoptosis regulator

6

13

Small-scale

0.714

High

155893

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

20

Small-scale

0.647

High

501016

IRF1
Interferon regulatory factor 1

2

7

Small-scale

0.601

High

841069

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

2

8

Small-scale

0.584

High

841061

TNF10
Tumor necrosis factor ligand superfamily member 10

1

8

Small-scale

0.575

High

841071

CUL3
Cullin-3

2

0

Small-scale

0.559

High

841077

ZDH17
Palmitoyltransferase ZDHHC17

1

3

High-throughput

0.541

High

528790

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

788162

CASP3
Caspase-3

1

13

Small-scale

0.501

High

841075

NOMO1
BOS complex subunit NOMO1

1

1

High-throughput

0.489

High

841081

RBM42
RNA-binding protein 42

1

2

High-throughput

0.489

High

260801

H2AY
Core histone macro-H2A.1

1

1

Small-scale

0.479

High

599636

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

3

Small-scale

0.479

High

786275

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

1

Small-scale

0.479

High

841063

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

1

Small-scale

0.479

High

841066

TRAF2
TNF receptor-associated factor 2

1

8

Small-scale

0.479

High

841070

IRF5
Interferon regulatory factor 5

1

7

Small-scale

0.479

High

841072

IRF3
Interferon regulatory factor 3

1

7

Small-scale

0.479

High

841074

PEA15
Astrocytic phosphoprotein PEA-15

1

0

Small-scale

0.458

High

841079

CASPA
Caspase-10

1

13

Small-scale

0.445

High

805342

IEX1
Radiation-inducible immediate-early gene IEX-1

1

0

Small-scale

0.438

High

147405

SOCS3
Suppressor of cytokine signaling 3

1

11

Small-scale

0.437

High

536494

IRF2
Interferon regulatory factor 2

1

7

Small-scale

0.437

High

831866

CEBPD
CCAAT/enhancer-binding protein delta

1

4

Small-scale

0.437

High

841062

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

2

High-throughput

0.437

High

841078

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

4

Small-scale

0.437

High

841067

PAK1
Serine/threonine-protein kinase PAK 1

1

0

Small-scale

0.426

High

532341

PPA5
Tartrate-resistant acid phosphatase type 5

1

0

High-throughput

0.282

High

841076

RBM48
RNA-binding protein 48

1

0

High-throughput

0.282

High

841064

CCZ1B
Vacuolar fusion protein CCZ1 homolog B

1

0

High-throughput

0.279

Low

841080

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

841065

RUNX1
Runt-related transcription factor 1

1

0

Small-scale

0.198

Low


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Last updated: 15 Jul 2024