Protein: MED8
Mediator of RNA polymerase II transcription subunit 8 (Mediator complex subunit 8)

Gene: MED8
Organism: Drosophila melanogaster
Interactions: 48
UniProt ID: A1ZBT5

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003712 - transcription coregulator activity
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0070847 - core mediator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

56297

MED6
Mediator of RNA polymerase II transcription subunit 6

1

1

High-throughput

0.618

High

56303

MED7
Mediator of RNA polymerase II transcription subunit 7

1

1

High-throughput

0.618

High

56324

MED11
Mediator of RNA polymerase II transcription subunit 11

1

2

High-throughput

0.618

High

56331

MED18
Mediator of RNA polymerase II transcription subunit 18

1

1

High-throughput

0.618

High

56294

MED29
Mediator of RNA polymerase II transcription subunit 29

2

1

High-throughput

0.576

High

56287

DORS
Embryonic polarity protein dorsal

1

0

High-throughput

0.486

High

56295

MED13
Mediator of RNA polymerase II transcription subunit 13

1

2

High-throughput

0.479

High

56300

EBI
F-box-like/WD repeat-containing protein ebi

1

1

High-throughput

0.479

High

56302

MED10
Mediator of RNA polymerase II transcription subunit 10

1

1

High-throughput

0.479

High

56310

MED17
Mediator of RNA polymerase II transcription subunit 17

1

1

High-throughput

0.479

High

56311

Q9VF03
Brahma associated protein 155 kDa

1

2

High-throughput

0.479

High

56316

MED27
Mediator of RNA polymerase II transcription subunit 27

1

1

High-throughput

0.479

High

56319

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.479

High

56322

CDK8
Cyclin-dependent kinase 8

1

3

High-throughput

0.479

High

56325

BAP60
Brahma-associated protein of 60 kDa

1

1

High-throughput

0.479

High

56327

MED30
Mediator of RNA polymerase II transcription subunit 30

1

2

High-throughput

0.479

High

56328

MED14
Mediator of RNA polymerase II transcription subunit 14

1

1

High-throughput

0.479

High

56329

MED23
Mediator of RNA polymerase II transcription subunit 23

1

1

High-throughput

0.479

High

56330

MED16
Mediator of RNA polymerase II transcription subunit 16

1

1

High-throughput

0.479

High

56332

MED15
Mediator of RNA polymerase II transcription subunit 15

1

1

High-throughput

0.479

High

56288

BRM
ATP-dependent helicase brm

1

0

High-throughput

0.458

High

56291

Q24090
GH08712p

1

0

High-throughput

0.458

High

56292

Q7JQT8
LD41464p

1

0

High-throughput

0.458

High

56308

MED25
Mediator of RNA polymerase II transcription subunit 25

1

0

High-throughput

0.458

High

53636

A1Z904
Dystrobrevin

1

3

High-throughput

0.451

High

56290

Q0E9B2
Dystrobrevin

1

3

High-throughput

0.439

High

56296

DMDE
Dystrophin, isoform E

1

3

High-throughput

0.439

High

56320

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

1

High-throughput

0.437

High

56293

Q7JWD6
Elongin-C

1

1

High-throughput

0.417

High

56309

DMDA
Dystrophin, isoforms A/C/F/G/H

1

3

High-throughput

0.417

High

56317

TR112
Multifunctional methyltransferase subunit TRM112-like protein

3

0

High-throughput

0.340

High

56305

VPS28
Vacuolar protein sorting-associated protein 28 homolog

2

0

High-throughput

0.310

High

56307

Q9VAY6
Pre-mRNA-splicing factor SPF27

2

0

High-throughput

0.310

High

56298

CSN3
COP9 signalosome complex subunit 3

1

0

High-throughput

0.265

Low

56306

Q9VA10
FI21270p1

1

0

High-throughput

0.265

Low

56312

Q9VG03
GH08448p

1

0

High-throughput

0.265

Low

56321

Q9VSZ1
GH05942p

1

0

High-throughput

0.265

Low

55260

A1ZAK9
P-element somatic inhibitor, isoform A

1

0

High-throughput

0.249

Low

56289

DSH
Segment polarity protein dishevelled

1

0

High-throughput

0.249

Low

56299

MESD
LDLR chaperone boca

1

0

High-throughput

0.249

Low

56301

Q960F7
SD03629p

1

0

High-throughput

0.249

Low

56304

LAR4
La-related protein Larp4B

1

0

High-throughput

0.249

Low

56314

Q9VL29
GEO11246p1

1

0

High-throughput

0.249

Low

56315

Q9VNF8
Protein transport protein SEC23

1

0

High-throughput

0.249

Low

56318

Q9VR42
Serine/threonine-protein kinase RIO3

1

0

High-throughput

0.249

Low

56323

Q9VUB7
PAX transcription activation domain interacting protein

1

0

High-throughput

0.249

Low

56326

Q9W0L7
ubiquitinyl hydrolase 1

1

0

High-throughput

0.249

Low

56313

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024