Protein: SPART
Spartin (Spastic paraplegia 20 protein) (Trans-activated by hepatitis C virus core protein 1)

Gene: SPART
Organism: Homo sapiens
Interactions: 98
UniProt ID: Q8N0X7

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005741 - mitochondrial outer membrane
GO:0005811 - lipid droplet
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1229716

ITCH
E3 ubiquitin-protein ligase Itchy homolog

7

10

Small-scale

0.747

High

1229721

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

6

10

Small-scale

0.738

High

1229727

SMUF1
E3 ubiquitin-protein ligase SMURF1

5

10

Small-scale

0.717

High

1229731

HECW2
E3 ubiquitin-protein ligase HECW2

2

10

High-throughput

0.628

High

502313

BIP
Endoplasmic reticulum chaperone BiP

2

7

Small-scale

0.621

High

498308

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

1

High-throughput

0.606

High

800599

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

2

3

High-throughput

0.606

High

1138837

OTU1
Ubiquitin thioesterase OTU1

2

3

High-throughput

0.606

High

1151616

OTU7B
OTU domain-containing protein 7B

2

6

High-throughput

0.606

High

1229714

OTUL
Ubiquitin thioesterase otulin

2

1

High-throughput

0.606

High

1229717

UBAC1
Ubiquitin-associated domain-containing protein 1

2

4

High-throughput

0.606

High

1229734

RABX5
Rab5 GDP/GTP exchange factor

2

1

High-throughput

0.606

High

1229732

POLK
DNA polymerase kappa

2

0

High-throughput

0.602

High

238184

PLIN3
Perilipin-3

2

0

Small-scale

0.598

High

1229725

SMUF2
E3 ubiquitin-protein ligase SMURF2

2

10

Small-scale

0.595

High

125574

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

10

Small-scale

0.586

High

228022

PRKN
E3 ubiquitin-protein ligase parkin

2

20

High-throughput

0.584

High

1229730

WWOX
WW domain-containing oxidoreductase

2

2

High-throughput

0.584

High

307543

EPN2
Epsin-2

2

0

High-throughput

0.580

High

1229718

DESI2
Deubiquitinase DESI2

2

0

High-throughput

0.580

High

582384

NUCL
Nucleolin

1

3

Small-scale

0.554

High

751720

GRP75
Stress-70 protein, mitochondrial

1

9

Small-scale

0.554

High

1229726

GPR35
G-protein coupled receptor 35

1

2

High-throughput

0.541

High

1229735

DP13A
DCC-interacting protein 13-alpha

1

2

High-throughput

0.541

High

164961

SC16A
Protein transport protein Sec16A

1

4

High-throughput

0.536

High

234831

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

2

Small-scale

0.536

High

316676

ACSL3
Fatty acid CoA ligase Acsl3

1

2

Small-scale

0.536

High

325271

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

3

Small-scale

0.536

High

443647

VIME
Vimentin

1

5

Small-scale

0.536

High

499916

CH60
60 kDa heat shock protein, mitochondrial

1

3

Small-scale

0.536

High

586848

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.536

High

863482

COPA
Coatomer subunit alpha

1

5

Small-scale

0.536

High

960881

CLH1
Clathrin heavy chain 1

1

1

Small-scale

0.536

High

1051608

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

3

Small-scale

0.536

High

1060820

IMB1
Importin subunit beta-1

1

3

Small-scale

0.536

High

1085433

MK06
Mitogen-activated protein kinase 6

1

7

High-throughput

0.536

High

1229720

KLC2
Kinesin light chain 2

1

6

Small-scale

0.536

High

787943

EPS15
Epidermal growth factor receptor substrate 15

1

4

Small-scale

0.527

High

779724

CCNF
Cyclin-F

1

6

High-throughput

0.515

High

124433

HIP1
Huntingtin-interacting protein 1

1

3

High-throughput

0.515

High

527604

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.515

High

1229736

SHLB1
Endophilin-B1

1

3

High-throughput

0.515

High

702943

KINH
Kinesin-1 heavy chain

1

0

Small-scale

0.513

High

313559

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

7

High-throughput

0.508

High

395159

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

1028396

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

6

Small-scale

0.501

High

1175018

TBA1A
Tubulin alpha-1A chain

1

20

Small-scale

0.501

High

279026

RAD17
Cell cycle checkpoint protein RAD17

1

3

High-throughput

0.489

High

595298

LMNB1
Lamin-B1

1

8

Small-scale

0.489

High

778210

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

5

Small-scale

0.489

High

322869

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

476039

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

16

High-throughput

0.479

High

518707

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.479

High

525987

IFM1
Interferon-induced transmembrane protein 1

1

2

High-throughput

0.479

High

553158

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

569870

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

668822

PML
Protein PML

1

5

High-throughput

0.479

High

718982

PHB1
Prohibitin 1

1

3

High-throughput

0.479

High

781567

CETN2
Centrin-2

1

6

High-throughput

0.479

High

791750

HD
Huntingtin

1

3

High-throughput

0.479

High

813600

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.479

High

998876

EP300
Histone acetyltransferase p300

1

7

High-throughput

0.479

High

1025457

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

5

High-throughput

0.479

High

1036727

SQSTM
Sequestosome-1

1

4

High-throughput

0.479

High

1042005

CUL3
Cullin-3

1

12

High-throughput

0.479

High

1056077

NBR1
Next to BRCA1 gene 1 protein

1

1

High-throughput

0.479

High

1078584

SMAD2
Mothers against decapentaplegic homolog 2

1

1

High-throughput

0.479

High

1080720

ZYX
Zyxin

1

3

High-throughput

0.479

High

1081094

CCDC6
Coiled-coil domain-containing protein 6

1

4

High-throughput

0.479

High

1101157

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

1151964

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1170766

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1200281

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

3

High-throughput

0.479

High

1200488

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1222459

SLX4
Structure-specific endonuclease subunit SLX4

1

4

High-throughput

0.479

High

1229710

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

4

High-throughput

0.479

High

1229711

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

1229712

AKAP1
A-kinase anchor protein 1, mitochondrial

1

3

High-throughput

0.479

High

1229713

CSN5
COP9 signalosome complex subunit 5

1

8

High-throughput

0.479

High

1229719

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

3

High-throughput

0.479

High

1229723

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.479

High

1229728

DJC11
DnaJ homolog subfamily C member 11

1

8

High-throughput

0.479

High

1229733

TBK1
Serine/threonine-protein kinase TBK1

1

4

High-throughput

0.479

High

532574

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

1229729

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

475098

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

16

Small-scale

0.445

High

853943

NCBP2
Nuclear cap-binding protein subunit 2

1

4

High-throughput

0.445

High

651660

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

720894

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

1026476

RFA4
Replication protein A 30 kDa subunit

1

4

High-throughput

0.437

High

1159390

FBX42
F-box only protein 42

1

4

High-throughput

0.437

High

1188545

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1229722

DJC25
DnaJ homolog subfamily C member 25

1

4

High-throughput

0.437

High

1229715

OTUB2
Ubiquitin thioesterase OTUB2

2

0

High-throughput

0.316

High

961722

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.279

Low

1229724

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.279

Low

258480

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.249

Low

473403

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024