HitPredict

Interactor 1: TLL (P18102)
Protein tailless (Nuclear receptor subfamily 2 group E member 2)
Gene: TLL

Interactor 2: Q86BH2 (Q86BH2)
Grunge, isoform C
Gene: Gug

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	24495972, 17503969
Identification Methods	protein complementation assay, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002121 - inter-male aggressive behavior GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 452 Dm			1 1988
+	Dm
		612458 TLL_DROME (1-452): 4.37e-116: 349: 100.00		Q8IQA6_DROME (1-1988): 0: 700: 98.89
+	Dm
		594750 7UP1_DROME (1-447): 7.89e-97: 303: 27.35		Q86BH2_DROME (1-1988): 0: 734: 100.00
+	Hs
		396838 ESR1_HUMAN (2-452): 9.32e-95: 299: 19.56		MTA3_HUMAN (4-417): 5.81e-71: 252: 18.14
+	Hs
		396042 ESR1_HUMAN (2-452): 9.32e-95: 299: 19.56		MTA1_HUMAN (4-414): 7.44e-60: 223: 18.06
+	Hs
		1367148 ESR2_HUMAN (34-449): 1.54e-83: 268: 23.08		MTA3_HUMAN (4-417): 5.81e-71: 252: 18.14
+	Hs
		316717 ESR1_HUMAN (2-452): 9.32e-95: 299: 19.56		MTA2_HUMAN (4-485): 1.16e-54: 206: 16.67
+	Hs
		404531 GCR_HUMAN (3-411): 2.06e-90: 292: 20.43		RCOR1_HUMAN (7-413): 3.57e-56: 206: 15.94
+	Hs
		1461146 NR2E1_HUMAN (20-452): 1.91e-94: 291: 37.70		RCOR1_HUMAN (7-413): 3.57e-56: 206: 15.94
+	Hs
		1102615 ESR2_HUMAN (34-449): 1.54e-83: 268: 23.08		MTA1_HUMAN (4-414): 7.44e-60: 223: 18.06
+	Hs
		316934 ESR2_HUMAN (34-449): 1.54e-83: 268: 23.08		MTA2_HUMAN (4-485): 1.16e-54: 206: 16.67
+	Hs
		404501 GCR_HUMAN (3-411): 2.06e-90: 292: 20.43		RCOR3_HUMAN (9-246): 2.84e-45: 174: 22.18
+	Hs
		928371 NR2E1_HUMAN (20-452): 1.91e-94: 291: 37.70		ATN1_HUMAN (1111-1847): 1.22e-40: 167: 21.13
+	Mm
		204255 NR2E1_MOUSE (20-452): 6.64e-95: 293: 37.70		ATN1_MOUSE (1111-1847): 2.13e-35: 150: 21.16
+	Hs
		395433 ESR1_HUMAN (2-452): 9.32e-95: 299: 19.56		MUC1_HUMAN (192-1109): 2.14e-33: 143: 13.36
+	Hs
		590324 ESR2_HUMAN (34-449): 1.54e-83: 268: 23.08		MUC1_HUMAN (192-1109): 2.14e-33: 143: 13.36
+	Mm
		1225430 NR6A1_MOUSE (34-442): 1.88e-97: 303: 21.60		NCOR2_MOUSE (123-1713): 2.91e-18: 94.4: 9.52
+	Hs
		404271 GCR_HUMAN (3-411): 2.06e-90: 292: 20.43		MUC16_HUMAN (192-1791): 3.14e-18: 94.4: 6.74
+	Hs
		396770 ESR1_HUMAN (2-452): 9.32e-95: 299: 19.56		MINT_HUMAN (187-1461): 1.01e-14: 82.7: 10.14
+	Hs
		404360 GCR_HUMAN (3-411): 2.06e-90: 292: 20.43		MINT_HUMAN (187-1461): 1.01e-14: 82.7: 10.14
+	Hs
		1454812 NR2E1_HUMAN (20-452): 1.91e-94: 291: 37.70		RERE_HUMAN (452-1429): 9.81e-15: 82.9: 10.68