Protein: AFF1
AF4/FMR2 family member 1 (ALL1-fused gene from chromosome 4 protein) (Protein AF-4) (Protein FEL) (Proto-oncogene AF4)

Gene: AFF1
Organism: Homo sapiens
Interactions: 54
UniProt ID: P51825

Gene Ontology (top 5):
GO:0008023 - transcription elongation factor complex
GO:0010468 - regulation of gene expression
GO:0032783 - super elongation complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

841575

CDK9
Cyclin-dependent kinase 9

13

11

Small-scale

0.983

High

850806

ENL
Protein ENL

8

15

Small-scale

0.970

High

788015

AF9
Protein AF-9

6

8

Small-scale

0.950

High

130150

ELL2
RNA polymerase II elongation factor ELL2

3

17

Small-scale

0.861

High

850827

ELL3
RNA polymerase II elongation factor ELL3

3

11

High-throughput

0.861

High

850799

AFF1
AF4/FMR2 family member 1

3

15

Small-scale

0.827

High

236727

CCNT1
Cyclin-T1

5

4

Small-scale

0.823

High

850828

AFF4
AF4/FMR2 family member 4

2

16

Small-scale

0.811

High

850819

CAMKV
CaM kinase-like vesicle-associated protein

2

4

High-throughput

0.726

High

850824

EAF1
ELL-associated factor 1

4

2

High-throughput

0.699

High

850803

ELL
RNA polymerase II elongation factor ELL

1

11

Small-scale

0.618

High

850820

Q8TD98
MLL/AF4 fusion protein

1

18

Small-scale

0.575

High

817642

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

4

High-throughput

0.574

High

850807

KMT2A
Histone-lysine N-methyltransferase 2A

2

20

Small-scale

0.574

High

850810

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

8

High-throughput

0.553

High

850816

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

7

Small-scale

0.535

High

244143

BRD4
Bromodomain-containing protein 4

2

10

Small-scale

0.533

High

303034

HEXI1
Protein HEXIM1

2

1

Small-scale

0.533

High

199100

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

7

Small-scale

0.501

High

313406

MED26
Mediator of RNA polymerase II transcription subunit 26

1

1

High-throughput

0.489

High

522596

MYH7
Myosin-7

1

3

High-throughput

0.489

High

850804

FGF12
Fibroblast growth factor 12

1

2

High-throughput

0.489

High

850809

HDAC1
Histone deacetylase 1

1

6

High-throughput

0.489

High

850818

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

5

High-throughput

0.489

High

850822

ZN526
Zinc finger protein 526

1

3

High-throughput

0.489

High

850826

E41L1
Band 4.1-like protein 1

1

9

High-throughput

0.489

High

850829

E41L3
Band 4.1-like protein 3

1

9

High-throughput

0.489

High

850800

RM12
Large ribosomal subunit protein bL12m

1

1

High-throughput

0.470

High

171374

SMAD9
Mothers against decapentaplegic homolog 9

1

6

High-throughput

0.464

High

850811

H31T
Histone H3.1t

1

12

Small-scale

0.457

High

308520

KI20A
Kinesin-like protein KIF20A

1

14

High-throughput

0.437

High

418062

NPM
Nucleophosmin

1

2

Small-scale

0.437

High

509926

VDR
Vitamin D3 receptor

1

20

Small-scale

0.437

High

569424

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.437

High

575343

EGR1
Early growth response protein 1

1

10

High-throughput

0.437

High

624818

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

Small-scale

0.437

High

640379

DDX6
Probable ATP-dependent RNA helicase DDX6

1

3

Small-scale

0.437

High

850802

AF10
Protein AF-10

1

5

Small-scale

0.437

High

850808

TF65
Transcription factor p65

1

7

Small-scale

0.437

High

850813

LARP7
La-related protein 7

1

2

Small-scale

0.437

High

850814

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.437

High

850815

CARM1
Histone-arginine methyltransferase CARM1

1

3

Small-scale

0.437

High

850821

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

Small-scale

0.437

High

850823

ESR2
Estrogen receptor beta

1

20

High-throughput

0.437

High

850825

NSD1
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

11

Small-scale

0.437

High

850801

ARFP1
Arfaptin-1

2

0

High-throughput

0.316

High

178905

MOT7
Monocarboxylate transporter 7

1

0

High-throughput

0.279

Low

299108

SASH1
SAM and SH3 domain-containing protein 1

1

0

Small-scale

0.251

Low

599783

5NTD
5'-nucleotidase

1

0

Small-scale

0.251

Low

664163

NEC1
Neuroendocrine convertase 1

1

0

Small-scale

0.249

Low

850805

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

850817

CCAR2
Cell cycle and apoptosis regulator protein 2

1

0

Small-scale

0.249

Low

850812

Q2Q440
MLL/ENL fusion protein

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024