Protein: TSR1
Pre-rRNA-processing protein TSR1 homolog

Gene: TSR1
Organism: Homo sapiens
Interactions: 237
UniProt ID: Q2NL82

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000479 - endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0003924 - GTPase activity
GO:0005525 - GTP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1102154

LTV1
Protein LTV1 homolog

3

0

High-throughput

0.827

High

1046842

BYST
Bystin

5

2

High-throughput

0.716

High

916616

RS6
Small ribosomal subunit protein eS6

4

3

High-throughput

0.694

High

1102168

RIOK2
Serine/threonine-protein kinase RIO2

1

4

High-throughput

0.691

High

834608

NU153
Nuclear pore complex protein Nup153

3

2

High-throughput

0.675

High

910446

RS14
Small ribosomal subunit protein uS11

3

4

High-throughput

0.675

High

1060768

IMB1
Importin subunit beta-1

3

1

High-throughput

0.675

High

1102117

RRP12
RRP12-like protein

3

2

High-throughput

0.675

High

445421

RSSA
Small ribosomal subunit protein uS2

3

6

High-throughput

0.667

High

550802

RS2
Small ribosomal subunit protein uS5

3

3

High-throughput

0.667

High

910691

RS23
Small ribosomal subunit protein uS12

1

0

High-throughput

0.656

High

1085746

IF16
Gamma-interferon-inducible protein 16

3

3

High-throughput

0.656

High

586784

CSK22
Casein kinase II subunit alpha'

2

3

High-throughput

0.628

High

616344

RS3
Small ribosomal subunit protein uS3

2

3

High-throughput

0.628

High

759680

RS19
Small ribosomal subunit protein eS19

2

4

High-throughput

0.628

High

907342

RS8
Small ribosomal subunit protein eS8

2

2

High-throughput

0.628

High

907940

RS16
Small ribosomal subunit protein uS9

2

2

High-throughput

0.628

High

911151

RS13
Small ribosomal subunit protein uS15

2

3

High-throughput

0.628

High

962119

HNRPU
Heterogeneous nuclear ribonucleoprotein U

2

2

High-throughput

0.628

High

133511

NOP56
Nucleolar protein 56

2

3

High-throughput

0.611

High

582319

NUCL
Nucleolin

2

1

High-throughput

0.611

High

898338

RS3A
Small ribosomal subunit protein eS1

2

5

High-throughput

0.611

High

920206

RS24
Small ribosomal subunit protein eS24

2

2

High-throughput

0.611

High

314646

PARN
Poly(A)-specific ribonuclease PARN

2

0

High-throughput

0.602

High

1102143

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

0

High-throughput

0.602

High

1102134

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

2

0

High-throughput

0.585

High

227613

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

244521

BRD4
Bromodomain-containing protein 4

2

1

High-throughput

0.584

High

346931

MYC
Myc proto-oncogene protein

2

2

High-throughput

0.584

High

552858

RFA2
Replication protein A 32 kDa subunit

2

1

High-throughput

0.584

High

603534

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

3

High-throughput

0.584

High

651347

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

1

High-throughput

0.584

High

720599

RFA3
Replication protein A 14 kDa subunit

2

1

High-throughput

0.584

High

918399

H2B1C
Histone H2B type 1-C/E/F/G/I

2

4

High-throughput

0.584

High

934823

H31
Histone H3.1

2

7

High-throughput

0.584

High

1102116

LARP7
La-related protein 7

2

4

High-throughput

0.584

High

1102178

ANLN
Anillin

2

1

High-throughput

0.584

High

1102122

RHBD2
Rhomboid domain-containing protein 2

2

0

High-throughput

0.580

High

1102190

CIDEB
Lipid transferase CIDEB

2

0

High-throughput

0.580

High

1102183

SLX9
Ribosome biogenesis protein SLX9 homolog

2

0

High-throughput

0.576

High

920878

RS30
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

1

2

High-throughput

0.575

High

369720

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

1051296

DCTN1
Dynactin subunit 1

2

0

High-throughput

0.559

High

127282

IPO5
Importin-5

1

1

High-throughput

0.536

High

152966

RIOK3
Serine/threonine-protein kinase RIO3

1

4

High-throughput

0.536

High

211755

BUD23
Probable 18S rRNA

1

1

High-throughput

0.536

High

229952

NUAK1
NUAK family SNF1-like kinase 1

1

1

High-throughput

0.536

High

403243

LA
Lupus La protein

1

3

High-throughput

0.536

High

418327

NPM
Nucleophosmin

1

2

High-throughput

0.536

High

444175

RS17
Small ribosomal subunit protein eS17

1

3

High-throughput

0.536

High

515282

KPSH1
Serine/threonine-protein kinase H1

1

1

High-throughput

0.536

High

796585

KSYK
Tyrosine-protein kinase SYK

1

2

High-throughput

0.536

High

806033

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.536

High

806873

RS9
Small ribosomal subunit protein uS4

1

4

High-throughput

0.536

High

807168

RS5
Small ribosomal subunit protein uS7

1

1

High-throughput

0.536

High

842888

TCPQ
T-complex protein 1 subunit theta

1

1

High-throughput

0.536

High

846478

BLK
Tyrosine-protein kinase Blk

1

1

High-throughput

0.536

High

850933

HDGF
Hepatoma-derived growth factor

1

2

High-throughput

0.536

High

893044

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.536

High

905648

RS7
Small ribosomal subunit protein eS7

1

3

High-throughput

0.536

High

907684

RS15A
Small ribosomal subunit protein uS8

1

3

High-throughput

0.536

High

910853

RS18
Small ribosomal subunit protein uS13

1

2

High-throughput

0.536

High

911400

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.536

High

914986

RS4X
Small ribosomal subunit protein eS4, X isoform

1

1

High-throughput

0.536

High

919992

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.536

High

920473

RS25
Small ribosomal subunit protein eS25

1

2

High-throughput

0.536

High

920779

RS28
Small ribosomal subunit protein eS28

1

2

High-throughput

0.536

High

929212

RS21
Small ribosomal subunit protein eS21

1

2

High-throughput

0.536

High

929486

RACK1
Small ribosomal subunit protein RACK1

1

6

High-throughput

0.536

High

934206

CSK21
Casein kinase II subunit alpha

1

2

High-throughput

0.536

High

940702

NOP14
Nucleolar protein 14

1

2

High-throughput

0.536

High

943119

KC1G2
Casein kinase I isoform gamma-2

1

4

High-throughput

0.536

High

983620

FAK1
Focal adhesion kinase 1

1

4

High-throughput

0.536

High

992581

ACK1
Activated CDC42 kinase 1

1

2

High-throughput

0.536

High

992795

SRSF1
Serine/arginine-rich splicing factor 1

1

4

High-throughput

0.536

High

1019773

ILF3
Interleukin enhancer-binding factor 3

1

5

High-throughput

0.536

High

1027894

DDX10
Probable ATP-dependent RNA helicase DDX10

1

6

High-throughput

0.536

High

1054355

RBM39
RNA-binding protein 39

1

1

High-throughput

0.536

High

1102127

RS27L
Ribosomal protein eS27-like

1

3

High-throughput

0.536

High

1102131

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.536

High

1102133

DHX37
Probable ATP-dependent RNA helicase DHX37

1

2

High-throughput

0.536

High

1102144

PSPC1
Paraspeckle component 1

1

1

High-throughput

0.536

High

1102165

RBM42
RNA-binding protein 42

1

1

High-throughput

0.536

High

1102166

NOC4L
Nucleolar complex protein 4 homolog

1

2

High-throughput

0.536

High

1102167

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

1

High-throughput

0.536

High

1102176

CBX8
Chromobox protein homolog 8

1

1

High-throughput

0.536

High

1102179

DDX21
Nucleolar RNA helicase 2

1

5

High-throughput

0.536

High

1102182

PNO1
RNA-binding protein PNO1

1

2

High-throughput

0.536

High

1102192

NOB1
RNA-binding protein NOB1

1

1

High-throughput

0.536

High

559117

H15
Histone H1.5

1

5

High-throughput

0.515

High

1102185

LYAR
Cell growth-regulating nucleolar protein

1

1

High-throughput

0.515

High

146824

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.513

High

383491

PRM2
Protamine-2

1

0

High-throughput

0.513

High

447950

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.513

High

508555

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

647904

MARK3
MAP/microtubule affinity-regulating kinase 3

1

0

High-throughput

0.513

High

649535

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

770859

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.513

High

828777

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

843218

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.513

High

867428

ICLN
Methylosome subunit pICln

1

0

High-throughput

0.513

High

876806

NP1L1
Nucleosome assembly protein 1-like 1

1

0

High-throughput

0.513

High

897749

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.513

High

943251

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.513

High

1063425

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.513

High

1077848

MYLK
Myosin light chain kinase, smooth muscle

1

0

High-throughput

0.513

High

1102129

CENPQ
Centromere protein Q

1

0

High-throughput

0.513

High

1102132

JAZF1
Juxtaposed with another zinc finger protein 1

1

0

High-throughput

0.513

High

1102155

AURKB
Aurora kinase B

1

0

High-throughput

0.513

High

1102186

IBTK
Inhibitor of Bruton tyrosine kinase

1

0

High-throughput

0.513

High

1102194

G3BP2
Ras GTPase-activating protein-binding protein 2

1

0

High-throughput

0.513

High

1102195

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.513

High

1102201

UBP16
Ubiquitin carboxyl-terminal hydrolase 16

1

0

High-throughput

0.513

High

902612

SUMO2
Small ubiquitin-related modifier 2

1

1

High-throughput

0.501

High

239591

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.493

High

278947

SPF30
Survival of motor neuron-related-splicing factor 30

1

0

High-throughput

0.493

High

485247

TZAP
Telomere zinc finger-associated protein

1

1

High-throughput

0.489

High

1102130

HDGR2
Hepatoma-derived growth factor-related protein 2

1

2

High-throughput

0.489

High

122799

MEN1
Menin

1

1

High-throughput

0.479

High

125496

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

1

High-throughput

0.479

High

148884

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

179658

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.479

High

239349

CC14B
Dual specificity protein phosphatase CDC14B

1

3

High-throughput

0.479

High

258048

DNJB6
DnaJ homolog subfamily B member 6

1

2

High-throughput

0.479

High

294892

RECQ4
ATP-dependent DNA helicase Q4

1

5

High-throughput

0.479

High

298557

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

322705

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

8

High-throughput

0.479

High

359995

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.479

High

374312

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

386836

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

433793

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.479

High

442201

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

2

High-throughput

0.479

High

569795

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

792994

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

4

High-throughput

0.479

High

808663

YAP1
Transcriptional coactivator YAP1

1

2

High-throughput

0.479

High

822278

KC1D
Casein kinase I isoform delta

1

3

High-throughput

0.479

High

824072

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

828246

CENPA
Histone H3-like centromeric protein A

1

7

High-throughput

0.479

High

829010

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

2

High-throughput

0.479

High

903268

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.479

High

908634

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

922193

RL31
Large ribosomal subunit protein eL31

1

3

High-throughput

0.479

High

944807

RED1
Double-stranded RNA-specific editase 1

1

6

High-throughput

0.479

High

952372

H33
Histone H3.3

1

7

High-throughput

0.479

High

1018513

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

2

High-throughput

0.479

High

1022109

NFX1
Transcriptional repressor NF-X1

1

1

High-throughput

0.479

High

1025770

TADBP
TAR DNA-binding protein 43

1

2

High-throughput

0.479

High

1027021

CBX3
Chromobox protein homolog 3

1

1

High-throughput

0.479

High

1059652

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

2

High-throughput

0.479

High

1063827

TNIP1
TNFAIP3-interacting protein 1

1

4

High-throughput

0.479

High

1064359

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1075597

TRBP2
RISC-loading complex subunit TARBP2

1

8

High-throughput

0.479

High

1102118

HABP4
Intracellular hyaluronan-binding protein 4

1

1

High-throughput

0.479

High

1102120

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

1102121

IFIX
Pyrin and HIN domain-containing protein 1

1

3

High-throughput

0.479

High

1102126

H32
Histone H3.2

1

7

High-throughput

0.479

High

1102138

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1102141

BICD2
Protein bicaudal D homolog 2

1

2

High-throughput

0.479

High

1102142

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1102145

DNJC9
DnaJ homolog subfamily C member 9

1

4

High-throughput

0.479

High

1102149

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1102150

KAT6A
Histone acetyltransferase KAT6A

1

3

High-throughput

0.479

High

1102151

FBXW7
F-box/WD repeat-containing protein 7

1

2

High-throughput

0.479

High

1102152

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

4

High-throughput

0.479

High

1102157

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

1102161

DNJC2
DnaJ homolog subfamily C member 2

1

2

High-throughput

0.479

High

1102162

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

1

High-throughput

0.479

High

1102172

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.479

High

1102174

LN28A
Protein lin-28 homolog A

1

5

High-throughput

0.479

High

1102175

RC3H2
Roquin-2

1

1

High-throughput

0.479

High

1102177

BRD7
Bromodomain-containing protein 7

1

2

High-throughput

0.479

High

1102180

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.479

High

1102187

DNJB4
DnaJ homolog subfamily B member 4

1

4

High-throughput

0.479

High

1102188

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1102189

TBK1
Serine/threonine-protein kinase TBK1

1

2

High-throughput

0.479

High

1102193

FZR1
Fizzy-related protein homolog

1

5

High-throughput

0.479

High

1102197

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

1102200

RBM8A
RNA-binding protein 8A

1

1

High-throughput

0.479

High

1046370

BMPR2
Bone morphogenetic protein receptor type-2

1

0

Small-scale

0.460

High

718898

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

793984

MATR3
Matrin-3

1

0

High-throughput

0.458

High

813508

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

835389

GSK3A
Glycogen synthase kinase-3 alpha

1

0

High-throughput

0.458

High

877749

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

898921

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.458

High

927100

1433Z
14-3-3 protein zeta/delta

1

0

High-throughput

0.458

High

959449

VIGLN
Vigilin

1

0

High-throughput

0.458

High

998786

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1036620

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1041691

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1071646

KS6A2
Ribosomal protein S6 kinase alpha-2

1

0

High-throughput

0.458

High

1102115

UVSSA
UV-stimulated scaffold protein A

1

0

Small-scale

0.458

High

1102123

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1102128

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1102136

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

1102137

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

1102146

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1102147

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1102148

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

0

High-throughput

0.458

High

1102153

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.458

High

1102159

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.458

High

1102160

CIC
Protein capicua homolog

1

0

High-throughput

0.458

High

1102163

BARD1
BRCA1-associated RING domain protein 1

1

0

High-throughput

0.458

High

1102169

TRI31
E3 ubiquitin-protein ligase TRIM31

1

0

High-throughput

0.458

High

1102170

IN80B
INO80 complex subunit B

1

0

High-throughput

0.458

High

1102181

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

1102184

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

1102198

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

90086

D6RAT0
Small ribosomal subunit protein eS1

1

5

High-throughput

0.445

High

402098

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

830378

KC1E
Casein kinase I isoform epsilon

1

4

High-throughput

0.445

High

879118

SUMO3
Small ubiquitin-related modifier 3

1

1

Small-scale

0.445

High

931189

YBOX1
Y-box-binding protein 1

1

5

High-throughput

0.445

High

1102139

RN169
E3 ubiquitin-protein ligase RNF169

1

1

Small-scale

0.445

High

1102164

RIOK1
Serine/threonine-protein kinase RIO1

1

4

High-throughput

0.445

High

517280

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

1055285

PDIA5
Protein disulfide-isomerase A5

1

1

High-throughput

0.437

High

1102124

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1102158

DNJC1
DnaJ homolog subfamily C member 1

1

6

High-throughput

0.437

High

1102173

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1102191

HECD1
E3 ubiquitin-protein ligase HECTD1

1

3

High-throughput

0.437

High

1102199

MAFB
Transcription factor MafB

1

1

High-throughput

0.437

High

306198

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

0

High-throughput

0.426

High

967038

XPC
DNA repair protein complementing XP-C cells

1

0

High-throughput

0.426

High

988916

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.426

High

1102119

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1102171

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

47418

RPSA2
Small ribosomal subunit protein uS2B

1

6

High-throughput

0.407

High

59195

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.279

Low

1102196

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.279

Low

352121

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

384934

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1053572

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

1102125

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.249

Low

1102135

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

1102140

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1102156

PRR11
Proline-rich protein 11

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024