Protein: PTPS
6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12)

Gene: PTPS, PTS
Organism: Homo sapiens
Interactions: 45
UniProt ID: Q03393

Gene Ontology (top 5):
GO:0003874 - 6-pyruvoyltetrahydropterin synthase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006520 - amino acid metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

976169

PTPS
6-pyruvoyl tetrahydrobiopterin synthase

11

4

Small-scale

0.982

High

132830

SDCB1
Syntenin-1

2

0

High-throughput

0.601

High

844018

FXR2
RNA-binding protein FXR2

2

0

High-throughput

0.593

High

976186

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.593

High

976184

AP2M1
AP-2 complex subunit mu

2

0

High-throughput

0.580

High

976185

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.580

High

750235

COIL
Coilin

1

0

High-throughput

0.549

High

976180

LNX1
E3 ubiquitin-protein ligase LNX

1

0

High-throughput

0.549

High

976191

THA10
THAP domain-containing protein 10

1

0

High-throughput

0.549

High

411683

LCK
Tyrosine-protein kinase Lck

2

0

High-throughput

0.547

High

976171

MK07
Mitogen-activated protein kinase 7

2

0

High-throughput

0.547

High

976183

ARHG1
Rho guanine nucleotide exchange factor 1

2

0

High-throughput

0.547

High

976176

ZFP1
Zinc finger protein 1 homolog

1

0

High-throughput

0.513

High

976177

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.513

High

976190

AGO4
Protein argonaute-4

1

0

High-throughput

0.513

High

976195

SAR1B
Small COPII coat GTPase SAR1B

1

0

High-throughput

0.513

High

976196

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.513

High

181847

SOCS1
Suppressor of cytokine signaling 1

1

1

Small-scale

0.479

High

976182

ASB5
Ankyrin repeat and SOCS box protein 5

1

1

High-throughput

0.479

High

976194

ASB1
Ankyrin repeat and SOCS box protein 1

1

1

High-throughput

0.479

High

242081

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

298443

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

325698

LATS1
Serine/threonine-protein kinase LATS1

1

0

High-throughput

0.458

High

369450

ESR1
Estrogen receptor

1

0

High-throughput

0.458

High

896044

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

908408

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

976170

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

976173

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.458

High

976174

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

976178

GOLI
E3 ubiquitin-protein ligase RNF130

1

0

High-throughput

0.458

High

976189

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

0

High-throughput

0.458

High

976192

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

960356

CDK16
Cyclin-dependent kinase 16

1

0

Small-scale

0.438

High

496889

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

976175

T2H2L
General transcription factor IIH subunit 2-like protein

3

0

High-throughput

0.347

High

976179

TEX29
Testis-expressed protein 29

3

0

High-throughput

0.347

High

439114

SYPH
Synaptophysin

2

0

High-throughput

0.328

High

976187

TAFA4
Chemokine-like protein TAFA-4

2

0

High-throughput

0.328

High

321991

ZMYM6
Zinc finger MYM-type protein 6

1

0

High-throughput

0.279

Low

976172

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.279

Low

976181

FNDC8
Fibronectin type III domain-containing protein 8

1

0

High-throughput

0.279

Low

976188

CIC
Protein capicua homolog

1

0

High-throughput

0.249

Low

976193

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low

362587

C1QC
Complement C1q subcomponent subunit C

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024