Protein: KPCG
Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)

Gene: KPCG, PRKCG
Organism: Homo sapiens
Interactions: 78
UniProt ID: P05129

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004697 - diacylglycerol-dependent serine/threonine kinase activity
GO:0004698 - calcium,diacylglycerol-dependent serine/threonine kinase activity
GO:0004712 - protein serine/threonine/tyrosine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

397135

KPCA
Protein kinase C alpha type

5

18

High-throughput

0.925

High

397123

HS90A
Heat shock protein HSP 90-alpha

3

20

High-throughput

0.817

High

397124

HS90B
Heat shock protein HSP 90-beta

3

20

High-throughput

0.817

High

397137

DNJA1
DnaJ homolog subfamily A member 1

2

13

High-throughput

0.737

High

397165

CDC37
Hsp90 co-chaperone Cdc37

2

12

High-throughput

0.737

High

397122

KPCB
Protein kinase C beta type

1

18

High-throughput

0.691

High

397162

RCN2
Reticulocalbin-2

2

6

High-throughput

0.659

High

397169

NOXA1
NADPH oxidase activator 1

1

3

High-throughput

0.656

High

397146

RGS2
Regulator of G-protein signaling 2

1

5

Small-scale

0.647

High

397151

GSK3A
Glycogen synthase kinase-3 alpha

1

19

Small-scale

0.647

High

397152

EPHB1
Ephrin type-B receptor 1

1

17

Small-scale

0.647

High

397159

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

20

Small-scale

0.647

High

397161

ARHG7
Rho guanine nucleotide exchange factor 7

1

10

Small-scale

0.647

High

397170

ARHGP
Rho guanine nucleotide exchange factor 25

1

15

Small-scale

0.647

High

397172

AFAP1
Actin filament-associated protein 1

1

5

Small-scale

0.647

High

397180

DNJC5
DnaJ homolog subfamily C member 5

1

2

Small-scale

0.647

High

397181

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

12

Small-scale

0.647

High

397171

DJC10
DnaJ homolog subfamily C member 10

1

7

High-throughput

0.618

High

397120

KPCG
Protein kinase C gamma type

1

17

High-throughput

0.618

High

397138

1433S
14-3-3 protein sigma

1

20

High-throughput

0.618

High

397144

STAT3
Signal transducer and activator of transcription 3

1

8

Small-scale

0.618

High

397147

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

19

Small-scale

0.618

High

397154

1433G
14-3-3 protein gamma

1

20

Small-scale

0.618

High

397155

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.618

High

397160

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

20

High-throughput

0.575

High

397167

H90B2
Putative heat shock protein HSP 90-beta 2

1

20

High-throughput

0.575

High

225827

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

2

15

High-throughput

0.571

High

323540

BAG2
BAG family molecular chaperone regulator 2

2

5

High-throughput

0.571

High

324988

AIFM1
Apoptosis-inducing factor 1, mitochondrial

2

3

High-throughput

0.571

High

388146

HSPB1
Heat shock protein beta-1

2

14

High-throughput

0.571

High

397121

ADT2
ADP/ATP translocase 2

2

12

High-throughput

0.571

High

397127

CH60
60 kDa heat shock protein, mitochondrial

2

5

High-throughput

0.571

High

397128

HSP7C
Heat shock cognate 71 kDa protein

2

12

High-throughput

0.571

High

397130

G6PD
Glucose-6-phosphate 1-dehydrogenase

2

1

High-throughput

0.571

High

397131

PRPS2
Ribose-phosphate pyrophosphokinase 2

2

15

High-throughput

0.571

High

397134

HSP76
Heat shock 70 kDa protein 6

2

12

High-throughput

0.571

High

397139

STIP1
Stress-induced-phosphoprotein 1

2

4

High-throughput

0.571

High

397143

LONM
Lon protease homolog, mitochondrial

2

5

High-throughput

0.571

High

397153

PRPS1
Ribose-phosphate pyrophosphokinase 1

2

15

High-throughput

0.571

High

397156

TBB4B
Tubulin beta-4B chain

2

20

High-throughput

0.571

High

397158

S25A3
Solute carrier family 25 member 3

2

17

High-throughput

0.571

High

397163

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

2

15

High-throughput

0.571

High

397166

PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial

2

2

High-throughput

0.571

High

397178

TCF25
Ribosome quality control complex subunit TCF25

2

1

High-throughput

0.571

High

397187

NS1BP
Influenza virus NS1A-binding protein

2

7

High-throughput

0.571

High

397148

GRIA4
Glutamate receptor 4

1

8

Small-scale

0.561

High

397168

RBP10
Ran-binding protein 10

1

7

Small-scale

0.561

High

397173

SAMD3
Sterile alpha motif domain-containing protein 3

1

0

High-throughput

0.556

High

397185

IBTK
Inhibitor of Bruton tyrosine kinase

1

10

Small-scale

0.553

High

397164

LTBP1
Latent-transforming growth factor beta-binding protein 1

2

5

High-throughput

0.521

High

277880

PIAS1
E3 SUMO-protein ligase PIAS1

1

4

High-throughput

0.515

High

397125

K1C19
Keratin, type I cytoskeletal 19

1

11

High-throughput

0.515

High

397174

CCHCR
Coiled-coil alpha-helical rod protein 1

1

8

High-throughput

0.508

High

397183

PICK1
PRKCA-binding protein

1

9

High-throughput

0.508

High

321863

RIGI
Antiviral innate immune response receptor RIG-I

1

11

Small-scale

0.501

High

393911

A4
Amyloid-beta precursor protein

1

9

High-throughput

0.501

High

396602

ITB2
Integrin beta-2

1

14

Small-scale

0.501

High

397126

TAU
Microtubule-associated protein tau

1

13

Small-scale

0.501

High

397129

TOP2A
DNA topoisomerase 2-alpha

1

6

Small-scale

0.501

High

397132

GFAP
Glial fibrillary acidic protein

1

11

Small-scale

0.501

High

397140

SDC2
Syndecan-2

1

4

Small-scale

0.501

High

397141

HSP74
Heat shock 70 kDa protein 4

1

19

Small-scale

0.501

High

397142

CTNB1
Catenin beta-1

1

6

Small-scale

0.501

High

397145

CASR
Extracellular calcium-sensing receptor

1

8

Small-scale

0.501

High

397157

DAB2
Disabled homolog 2

1

16

Small-scale

0.501

High

397179

TRIM5
Tripartite motif-containing protein 5

1

9

Small-scale

0.501

High

397182

UBE2T
Ubiquitin-conjugating enzyme E2 T

1

2

Small-scale

0.501

High

397186

FBX7
F-box only protein 7

1

4

High-throughput

0.501

High

397175

TCP1L
T-complex protein 10A homolog 1

1

0

High-throughput

0.493

High

130013

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.486

High

397133

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

3

Small-scale

0.479

High

397149

GBRA4
Gamma-aminobutyric acid receptor subunit alpha-4

1

3

Small-scale

0.479

High

397177

RANB9
Ran-binding protein 9

1

7

Small-scale

0.479

High

397184

SCN3A
Sodium channel protein type 3 subunit alpha

1

1

Small-scale

0.457

High

397136

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

7

Small-scale

0.457

High

397150

HSP77
Putative heat shock 70 kDa protein 7

1

15

High-throughput

0.445

High

397176

F167A
Protein FAM167A

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024