Protein: ZN644
Zinc finger protein 644 (Zinc finger motif enhancer-binding protein 2) (Zep-2)

Gene: ZN644, ZNF644
Organism: Homo sapiens
Interactions: 177
UniProt ID: Q9H582

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001222 - transcription corepressor binding
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1230902

Z324B
Zinc finger protein 324B

2

17

High-throughput

0.811

High

1434506

ZN223
Zinc finger protein 223

2

16

High-throughput

0.811

High

675677

TYY1
Transcriptional repressor protein YY1

2

17

High-throughput

0.789

High

1097560

CBX3
Chromobox protein homolog 3

4

20

High-throughput

0.699

High

1332345

ZN383
Zinc finger protein 383

1

10

High-throughput

0.691

High

1434514

ZN281
Zinc finger protein 281

1

13

High-throughput

0.691

High

998806

H31
Histone H3.1

4

11

High-throughput

0.676

High

1014203

CBX1
Chromobox protein homolog 1

3

20

High-throughput

0.675

High

1395184

ZN462
Zinc finger protein 462

3

6

High-throughput

0.675

High

1396304

EHMT2
Histone-lysine N-methyltransferase EHMT2

3

11

High-throughput

0.675

High

644054

FBRL
rRNA 2'-O-methyltransferase fibrillarin

3

4

High-throughput

0.667

High

1324713

MIER2
Mesoderm induction early response protein 2

3

4

High-throughput

0.667

High

1434489

SUV92
Histone-lysine N-methyltransferase SUV39H2

3

10

High-throughput

0.667

High

216542

SUV91
Histone-lysine N-methyltransferase SUV39H1

2

11

High-throughput

0.628

High

1418393

PCGF6
Polycomb group RING finger protein 6

2

4

High-throughput

0.628

High

1434494

SSF1
Suppressor of SWI4 1 homolog

2

3

High-throughput

0.628

High

1434516

LMBL1
Lethal(3)malignant brain tumor-like protein 1

2

1

High-throughput

0.628

High

244110

ZN292
Zinc finger protein 292

1

19

High-throughput

0.618

High

339856

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.618

High

538471

EGR2
E3 SUMO-protein ligase EGR2

1

18

High-throughput

0.618

High

613182

EGR1
Early growth response protein 1

1

14

High-throughput

0.618

High

944742

KLF3
Krueppel-like factor 3

1

18

High-throughput

0.618

High

1095357

RLF
Zinc finger protein Rlf

1

15

High-throughput

0.618

High

1118683

KLF9
Krueppel-like factor 9

1

18

High-throughput

0.618

High

1405731

KLF6
Krueppel-like factor 6

1

20

High-throughput

0.618

High

1416908

KLF16
Krueppel-like factor 16

1

20

High-throughput

0.618

High

1434505

KLF15
Krueppel-like factor 15

1

20

High-throughput

0.618

High

1434517

KLF12
Krueppel-like factor 12

1

19

High-throughput

0.618

High

345002

WIZ
Protein Wiz

2

9

High-throughput

0.611

High

872745

SOX2
Transcription factor SOX-2

2

15

High-throughput

0.611

High

1017209

H33
Histone H3.3

2

11

High-throughput

0.611

High

1100378

TIF1B
Transcription intermediary factor 1-beta

2

20

High-throughput

0.611

High

1235080

ADNP2
Activity-dependent neuroprotector homeobox protein 2

2

7

High-throughput

0.611

High

1395208

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

2

2

High-throughput

0.611

High

1432091

ADNP
Activity-dependent neuroprotector homeobox protein

2

1

High-throughput

0.611

High

1434493

EHMT1
Histone-lysine N-methyltransferase EHMT1

2

10

High-throughput

0.611

High

1434500

ZMYM2
Zinc finger MYM-type protein 2

2

2

High-throughput

0.611

High

1434511

CDYL
Chromodomain Y-like protein

2

20

Small-scale

0.611

High

1292807

SKAP1
Src kinase-associated phosphoprotein 1

3

2

High-throughput

0.609

High

1057908

RL18
Large ribosomal subunit protein eL18

2

0

High-throughput

0.602

High

143257

NFIB
Nuclear factor 1 B-type

2

15

High-throughput

0.584

High

474292

NFIC
Nuclear factor 1 C-type

2

15

High-throughput

0.584

High

1088019

NFIA
Nuclear factor 1 A-type

2

15

High-throughput

0.584

High

1133662

NFIX
Nuclear factor 1 X-type

2

15

High-throughput

0.584

High

1233946

Q6ICH2
single-stranded DNA cytosine deaminase

2

5

High-throughput

0.584

High

787342

ACV1B
Activin receptor type-1B

1

0

High-throughput

0.578

High

1093049

CDC16
Cell division cycle protein 16 homolog

2

1

High-throughput

0.574

High

1355882

XAGE3
X antigen family member 3

2

7

High-throughput

0.574

High

1392385

XAGE2
X antigen family member 2

2

7

High-throughput

0.574

High

1411296

LZTS2
Leucine zipper putative tumor suppressor 2

2

3

High-throughput

0.574

High

338962

CBX6
Chromobox protein homolog 6

1

20

High-throughput

0.536

High

502129

H2AZ
Histone H2A.Z

1

4

High-throughput

0.536

High

648378

USF1
Upstream stimulatory factor 1

1

4

High-throughput

0.536

High

659588

CRCM
Colorectal mutant cancer protein

1

2

High-throughput

0.536

High

853408

CBX5
Chromobox protein homolog 5

1

20

High-throughput

0.536

High

1065431

SSRP1
FACT complex subunit SSRP1

1

10

High-throughput

0.536

High

1163205

H2B2E
Histone H2B type 2-E

1

8

High-throughput

0.536

High

1329870

SIR6
NAD-dependent protein deacylase sirtuin-6

1

3

High-throughput

0.536

High

1368124

HDAC2
Histone deacetylase 2

1

2

High-throughput

0.536

High

1382529

TRI52
E3 ubiquitin-protein ligase TRIM52

1

18

High-throughput

0.536

High

1434498

FOXJ2
Forkhead box protein J2

1

1

High-throughput

0.536

High

601857

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.513

High

1233797

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.513

High

1238820

TECT3
Tectonic-3

1

0

High-throughput

0.513

High

1324596

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.513

High

214943

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

0

High-throughput

0.493

High

1434503

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.493

High

317751

NOL4
Nucleolar protein 4

1

1

High-throughput

0.489

High

859999

RL28
Large ribosomal subunit protein eL28

1

5

High-throughput

0.489

High

890260

TIG1
Retinoic acid receptor responder protein 1

1

3

High-throughput

0.489

High

1196248

GAG2E
G antigen 2E

1

7

High-throughput

0.489

High

1340669

NEDD1
Protein NEDD1

1

3

High-throughput

0.489

High

1434501

GGE2D
G antigen 2D

1

7

High-throughput

0.489

High

1434510

PNMA2
Paraneoplastic antigen Ma2

1

3

High-throughput

0.489

High

65384

DPRX
Divergent paired-related homeobox

1

6

High-throughput

0.479

High

129430

MEN1
Menin

1

3

High-throughput

0.479

High

181564

TBXT
T-box transcription factor T

1

3

High-throughput

0.479

High

210117

CRX
Cone-rod homeobox protein

1

14

High-throughput

0.479

High

225110

TLX3
T-cell leukemia homeobox protein 3

1

17

High-throughput

0.479

High

226599

TLX2
T-cell leukemia homeobox protein 2

1

12

High-throughput

0.479

High

239998

SOX15
Transcription factor SOX-15

1

15

High-throughput

0.479

High

274754

DNJB6
DnaJ homolog subfamily B member 6

1

5

High-throughput

0.479

High

298956

DNJB5
DnaJ homolog subfamily B member 5

1

5

High-throughput

0.479

High

414628

P53
Cellular tumor antigen p53

1

4

High-throughput

0.479

High

487755

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

519422

MYB
Transcriptional activator Myb

1

1

High-throughput

0.479

High

581729

MYOD1
Myoblast determination protein 1

1

3

High-throughput

0.479

High

607110

CEBPB
CCAAT/enhancer-binding protein beta

1

7

High-throughput

0.479

High

662278

PAX7
Paired box protein Pax-7

1

8

High-throughput

0.479

High

662499

GATA2
Endothelial transcription factor GATA-2

1

3

High-throughput

0.479

High

685348

PAX6
Paired box protein Pax-6

1

6

High-throughput

0.479

High

697252

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

High-throughput

0.479

High

703199

TEAD1
Transcriptional enhancer factor TEF-1

1

1

High-throughput

0.479

High

725319

TLX1
T-cell leukemia homeobox protein 1

1

13

High-throughput

0.479

High

739030

ELF1
ETS-related transcription factor Elf-1

1

10

High-throughput

0.479

High

800103

COIL
Coilin

1

4

High-throughput

0.479

High

832574

ETV3
ETS translocation variant 3

1

9

High-throughput

0.479

High

834054

HNF4A
Hepatocyte nuclear factor 4-alpha

1

9

High-throughput

0.479

High

837090

ELK3
ETS domain-containing protein Elk-3

1

10

High-throughput

0.479

High

877562

LHX1
LIM/homeobox protein Lhx1

1

7

High-throughput

0.479

High

883689

CENPA
Histone H3-like centromeric protein A

1

11

High-throughput

0.479

High

887223

CEBPA
CCAAT/enhancer-binding protein alpha

1

7

High-throughput

0.479

High

895798

LHX2
LIM/homeobox protein Lhx2

1

8

High-throughput

0.479

High

938505

PAX9
Paired box protein Pax-9

1

5

High-throughput

0.479

High

980321

H4
Histone H4

1

3

High-throughput

0.479

High

981095

H2B1C
Histone H2B type 1-C/E/F/G/I

1

8

High-throughput

0.479

High

982826

RS24
Small ribosomal subunit protein eS24

1

1

High-throughput

0.479

High

990733

1433Z
14-3-3 protein zeta/delta

1

7

High-throughput

0.479

High

995271

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.479

High

1005094

RNF4
E3 ubiquitin-protein ligase RNF4

1

14

High-throughput

0.479

High

1024184

TFAM
Transcription factor A, mitochondrial

1

10

High-throughput

0.479

High

1037898

HEN1
Helix-loop-helix protein 1

1

6

High-throughput

0.479

High

1056651

PAX8
Paired box protein Pax-8

1

9

High-throughput

0.479

High

1094737

CAF1A
Chromatin assembly factor 1 subunit A

1

2

High-throughput

0.479

High

1094816

CAF1B
Chromatin assembly factor 1 subunit B

1

2

High-throughput

0.479

High

1114298

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1132979

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

1152741

ELF2
ETS-related transcription factor Elf-2

1

8

High-throughput

0.479

High

1236167

Z280D
Zinc finger protein 280D

1

16

High-throughput

0.479

High

1240777

PMF1
Polyamine-modulated factor 1

1

1

High-throughput

0.479

High

1276788

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1277237

POGZ
Pogo transposable element with ZNF domain

1

9

High-throughput

0.479

High

1313430

SMC5
Structural maintenance of chromosomes protein 5

1

4

High-throughput

0.479

High

1314420

SLX4
Structure-specific endonuclease subunit SLX4

1

3

High-throughput

0.479

High

1379949

LHX4
LIM/homeobox protein Lhx4

1

8

High-throughput

0.479

High

1387558

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

3

High-throughput

0.479

High

1394505

NSL1
Kinetochore-associated protein NSL1 homolog

1

1

High-throughput

0.479

High

1405433

FEV
Protein FEV

1

7

High-throughput

0.479

High

1405637

ELF4
ETS-related transcription factor Elf-4

1

10

High-throughput

0.479

High

1429540

MIS12
Protein MIS12 homolog

1

1

High-throughput

0.479

High

1433041

DSN1
Kinetochore-associated protein DSN1 homolog

1

1

High-throughput

0.479

High

1434490

SOX17
Transcription factor SOX-17

1

15

High-throughput

0.479

High

1434496

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

1434497

VSX1
Visual system homeobox 1

1

8

High-throughput

0.479

High

1434499

LHX3
LIM/homeobox protein Lhx3

1

8

High-throughput

0.479

High

1434502

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

1

1

Small-scale

0.479

High

1434504

XPO7
Exportin-7

1

8

High-throughput

0.479

High

1434507

FBW1B
F-box/WD repeat-containing protein 11

1

1

High-throughput

0.479

High

1434509

ELF5
ETS-related transcription factor Elf-5

1

9

High-throughput

0.479

High

1434512

ASF1A
Histone chaperone ASF1A

1

1

High-throughput

0.479

High

1434515

ZN330
Zinc finger protein 330

1

3

High-throughput

0.479

High

1434518

ETV7
Transcription factor ETV7

1

10

High-throughput

0.479

High

1434519

CDY2
Testis-specific chromodomain protein Y 2

1

6

High-throughput

0.479

High

589683

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

946532

YBEY
Endoribonuclease YbeY

1

0

High-throughput

0.458

High

981698

RAN
GTP-binding nuclear protein Ran

1

0

High-throughput

0.458

High

1037819

IRF8
Interferon regulatory factor 8

1

0

High-throughput

0.458

High

1216487

AHDC1
Transcription factor Gibbin

1

0

High-throughput

0.458

High

1244831

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1332181

SCAI
Protein SCAI

1

0

High-throughput

0.458

High

1434491

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

73452

B2CML4
single-stranded DNA cytosine deaminase

1

5

High-throughput

0.445

High

1103375

CTBP1
C-terminal-binding protein 1

1

4

High-throughput

0.445

High

1383329

ABC3D
DNA dC->dU-editing enzyme APOBEC-3D

1

5

High-throughput

0.445

High

191091

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

4

High-throughput

0.437

High

391777

PRPC
Salivary acidic proline-rich phosphoprotein 1/2

1

1

High-throughput

0.437

High

1212464

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

1

High-throughput

0.437

High

1241957

FBX42
F-box only protein 42

1

2

High-throughput

0.437

High

1308375

CCD71
Coiled-coil domain-containing protein 71

1

1

Small-scale

0.437

High

1338960

NUP43
Nucleoporin Nup43

1

2

High-throughput

0.437

High

1428621

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.437

High

1434495

DJC17
DnaJ homolog subfamily C member 17

1

9

High-throughput

0.437

High

1434492

MINY3
Ubiquitin carboxyl-terminal hydrolase MINDY-3

3

0

High-throughput

0.347

High

270685

ATP9A
Probable phospholipid-transporting ATPase IIA

1

0

High-throughput

0.279

Low

366265

FA9
Coagulation factor IX

1

0

High-throughput

0.279

Low

1178888

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

1231287

BLT3A
Bridge-like lipid transfer protein family member 3A

1

0

High-throughput

0.279

Low

1248237

CSPG4
Chondroitin sulfate proteoglycan 4

1

0

High-throughput

0.279

Low

1328627

PAR16
Protein mono-ADP-ribosyltransferase PARP16

1

0

High-throughput

0.279

Low

1390354

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1412258

NOL10
Nucleolar protein 10

1

0

High-throughput

0.279

Low

1434508

TF3C4
General transcription factor 3C polypeptide 4

1

0

High-throughput

0.279

Low

1434513

TDRKH
Tudor and KH domain-containing protein

1

0

High-throughput

0.279

Low

1204393

SGO1
Shugoshin 1

1

0

High-throughput

0.249

Low

1311858

DHX40
Probable ATP-dependent RNA helicase DHX40

1

0

High-throughput

0.249

Low

1357557

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low

1384877

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025