Protein: WIZ
Protein Wiz (Widely-interspaced zinc finger-containing protein) (Zinc finger protein 803)

Gene: WIZ
Organism: Homo sapiens
Interactions: 208
UniProt ID: O95785

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001222 - transcription corepressor binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

344931

CTBP1
C-terminal-binding protein 1

8

3

Small-scale

0.748

High

344983

EHMT2
Histone-lysine N-methyltransferase EHMT2

7

10

Small-scale

0.747

High

345016

TRI10
Tripartite motif-containing protein 10

4

9

High-throughput

0.691

High

344914

H31
Histone H3.1

4

13

High-throughput

0.676

High

344917

CBX1
Chromobox protein homolog 1

3

20

High-throughput

0.675

High

344933

HDAC1
Histone deacetylase 1

3

3

High-throughput

0.675

High

344981

ZN462
Zinc finger protein 462

3

6

High-throughput

0.675

High

344849

CATG
Cathepsin G

3

1

High-throughput

0.667

High

344930

CBX3
Chromobox protein homolog 3

3

20

High-throughput

0.667

High

344960

ZBT46
Zinc finger and BTB domain-containing protein 46

3

15

High-throughput

0.667

High

344966

MIER2
Mesoderm induction early response protein 2

3

4

High-throughput

0.667

High

344910

H4
Histone H4

3

2

High-throughput

0.640

High

344887

CBX5
Chromobox protein homolog 5

2

20

Small-scale

0.628

High

344976

HDAC2
Histone deacetylase 2

2

3

High-throughput

0.628

High

345004

IKZF5
Zinc finger protein Pegasus

2

16

High-throughput

0.628

High

345028

LMBL1
Lethal(3)malignant brain tumor-like protein 1

2

1

High-throughput

0.628

High

345009

COPRS
Coordinator of PRMT5 and differentiation stimulator

3

0

High-throughput

0.616

High

344852

H2AZ
Histone H2A.Z

2

4

High-throughput

0.611

High

344870

TYY1
Transcriptional repressor protein YY1

2

19

High-throughput

0.611

High

344905

CTBP2
C-terminal-binding protein 2

2

3

Small-scale

0.611

High

344918

H33
Histone H3.3

2

13

High-throughput

0.611

High

344952

RICTR
Rapamycin-insensitive companion of mTOR

2

1

Small-scale

0.611

High

344996

RPA49
DNA-directed RNA polymerase I subunit RPA49

2

1

High-throughput

0.611

High

345002

ZN644
Zinc finger protein 644

2

9

High-throughput

0.611

High

345007

EHMT1
Histone-lysine N-methyltransferase EHMT1

2

10

High-throughput

0.611

High

345024

CDYL
Chromodomain Y-like protein

2

17

Small-scale

0.611

High

128698

MEN1
Menin

2

2

High-throughput

0.584

High

344850

NFIC
Nuclear factor 1 C-type

2

14

High-throughput

0.584

High

344856

ANDR
Androgen receptor

2

12

High-throughput

0.584

High

344891

SOX2
Transcription factor SOX-2

2

12

Small-scale

0.584

High

344907

KLF3
Krueppel-like factor 3

2

20

High-throughput

0.584

High

344927

NFIA
Nuclear factor 1 A-type

2

14

High-throughput

0.584

High

344938

NFIX
Nuclear factor 1 X-type

2

14

High-throughput

0.584

High

344964

SLX4
Structure-specific endonuclease subunit SLX4

2

1

High-throughput

0.584

High

344972

XAGE3
X antigen family member 3

2

7

High-throughput

0.574

High

344979

XAGE2
X antigen family member 2

2

7

High-throughput

0.574

High

344847

ESR1
Estrogen receptor

2

12

High-throughput

0.571

High

129630

CBX4
E3 SUMO-protein ligase CBX4

1

20

High-throughput

0.536

High

133072

FOXE1
Forkhead box protein E1

1

2

High-throughput

0.536

High

344842

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.536

High

344853

H2A1
Histone H2A type 1

1

2

High-throughput

0.536

High

344868

APC
Adenomatous polyposis coli protein

1

2

High-throughput

0.536

High

344888

NOTC1
Neurogenic locus notch homolog protein 1

1

20

High-throughput

0.536

High

344897

TIG1
Retinoic acid receptor responder protein 1

1

3

High-throughput

0.536

High

344903

FOXG1
Forkhead box protein G1

1

1

High-throughput

0.536

High

344908

MAX
Protein max

1

4

High-throughput

0.536

High

344939

NUMA1
Nuclear mitotic apparatus protein 1

1

5

High-throughput

0.536

High

344943

H2B2E
Histone H2B type 2-E

1

5

High-throughput

0.536

High

344958

MIER3
Mesoderm induction early response protein 3

1

4

High-throughput

0.536

High

344965

MIER1
Mesoderm induction early response protein 1

1

4

High-throughput

0.536

High

344968

SIR6
NAD-dependent protein deacylase sirtuin-6

1

3

High-throughput

0.536

High

344969

CDYL2
Chromodomain Y-like protein 2

1

4

High-throughput

0.536

High

344989

MEP50
Methylosome protein WDR77

1

2

High-throughput

0.536

High

344995

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

1

1

High-throughput

0.536

High

344904

PKNX1
Homeobox protein PKNOX1

1

0

High-throughput

0.518

High

168025

RGS12
Regulator of G-protein signaling 12

1

0

High-throughput

0.513

High

344865

TBG1
Tubulin gamma-1 chain

1

0

High-throughput

0.513

High

344901

ICLN
Methylosome subunit pICln

1

0

High-throughput

0.513

High

344902

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.513

High

344916

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

0

High-throughput

0.513

High

344924

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

0

High-throughput

0.513

High

344934

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

344936

BOP1
Ribosome biogenesis protein BOP1

1

0

High-throughput

0.513

High

344954

UBP45
Ubiquitin carboxyl-terminal hydrolase 45

1

0

High-throughput

0.513

High

344990

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.513

High

216361

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

10

High-throughput

0.508

High

344848

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.508

High

344861

RCC1
Regulator of chromosome condensation

1

1

High-throughput

0.508

High

344880

CDN1A
Cyclin-dependent kinase inhibitor 1

1

2

High-throughput

0.508

High

344890

RS10
Small ribosomal subunit protein eS10

1

3

High-throughput

0.508

High

344941

T22D1
TSC22 domain family protein 1

1

1

High-throughput

0.508

High

344942

SMN
Survival motor neuron protein

1

1

High-throughput

0.508

High

345003

SUV92
Histone-lysine N-methyltransferase SUV39H2

1

9

High-throughput

0.508

High

344862

NUCL
Nucleolin

1

0

High-throughput

0.493

High

344944

GAG2E
G antigen 2E

1

7

High-throughput

0.489

High

345017

GGE2D
G antigen 2D

1

7

High-throughput

0.489

High

345023

PNMA2
Paraneoplastic antigen Ma2

1

3

High-throughput

0.489

High

325416

RPP14
Ribonuclease P protein subunit p14

1

0

High-throughput

0.486

High

344932

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.486

High

345008

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.486

High

344985

CRBN
Protein cereblon

1

0

Small-scale

0.480

High

142775

NFIB
Nuclear factor 1 B-type

1

14

High-throughput

0.479

High

181483

TBXT
T-box transcription factor T

1

1

High-throughput

0.479

High

190782

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

3

High-throughput

0.479

High

209936

CRX
Cone-rod homeobox protein

1

11

High-throughput

0.479

High

224923

TLX3
T-cell leukemia homeobox protein 3

1

12

High-throughput

0.479

High

226505

TLX2
T-cell leukemia homeobox protein 2

1

9

High-throughput

0.479

High

239910

SOX15
Transcription factor SOX-15

1

12

High-throughput

0.479

High

277496

H2AY
Core histone macro-H2A.1

1

5

High-throughput

0.479

High

285018

EED
Polycomb protein EED

1

4

High-throughput

0.479

High

339627

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

344841

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

14

High-throughput

0.479

High

344843

FOS
Protein c-Fos

1

2

High-throughput

0.479

High

344844

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

344845

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

6

High-throughput

0.479

High

344851

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

344855

MYB
Transcriptional activator Myb

1

1

High-throughput

0.479

High

344857

EGR2
E3 SUMO-protein ligase EGR2

1

19

High-throughput

0.479

High

344858

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

344859

MYOD1
Myoblast determination protein 1

1

4

High-throughput

0.479

High

344860

H2AX
Histone H2AX

1

3

High-throughput

0.479

High

344863

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

4

High-throughput

0.479

High

344866

GATA2
Endothelial transcription factor GATA-2

1

3

High-throughput

0.479

High

344867

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

3

High-throughput

0.479

High

344869

BRD2
Bromodomain-containing protein 2

1

1

High-throughput

0.479

High

344871

PAX6
Paired box protein Pax-6

1

5

High-throughput

0.479

High

344872

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

344873

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

High-throughput

0.479

High

344874

TEAD1
Transcriptional enhancer factor TEF-1

1

1

High-throughput

0.479

High

344875

TLX1
T-cell leukemia homeobox protein 1

1

10

High-throughput

0.479

High

344876

H2B1B
Histone H2B type 1-B

1

5

High-throughput

0.479

High

344877

HNF1B
Hepatocyte nuclear factor 1-beta

1

8

High-throughput

0.479

High

344878

BRCA1
Breast cancer type 1 susceptibility protein

1

7

High-throughput

0.479

High

344879

COIL
Coilin

1

3

High-throughput

0.479

High

344881

HNF4A
Hepatocyte nuclear factor 4-alpha

1

6

High-throughput

0.479

High

344882

ELK3
ETS domain-containing protein Elk-3

1

10

High-throughput

0.479

High

344886

GATA4
Transcription factor GATA-4

1

3

High-throughput

0.479

High

344892

LHX1
LIM/homeobox protein Lhx1

1

7

High-throughput

0.479

High

344893

CDK8
Cyclin-dependent kinase 8

1

1

High-throughput

0.479

High

344894

CENPA
Histone H3-like centromeric protein A

1

13

High-throughput

0.479

High

344896

CEBPA
CCAAT/enhancer-binding protein alpha

1

7

High-throughput

0.479

High

344898

LHX2
LIM/homeobox protein Lhx2

1

9

High-throughput

0.479

High

344909

RS6
Small ribosomal subunit protein eS6

1

3

High-throughput

0.479

High

344911

H2B1C
Histone H2B type 1-C/E/F/G/I

1

5

High-throughput

0.479

High

344912

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.479

High

344919

TFAM
Transcription factor A, mitochondrial

1

7

High-throughput

0.479

High

344923

EWS
RNA-binding protein EWS

1

2

High-throughput

0.479

High

344925

HEN1
Helix-loop-helix protein 1

1

7

High-throughput

0.479

High

344926

HME1
Homeobox protein engrailed-1

1

2

High-throughput

0.479

High

344928

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.479

High

344929

CAF1B
Chromatin assembly factor 1 subunit B

1

2

High-throughput

0.479

High

344935

CUL3
Cullin-3

1

20

High-throughput

0.479

High

344937

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

344940

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.479

High

344946

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

1

High-throughput

0.479

High

344949

RN123
E3 ubiquitin-protein ligase RNF123

1

3

High-throughput

0.479

High

344951

PMF1
Polyamine-modulated factor 1

1

1

High-throughput

0.479

High

344953

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

344956

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

344957

POGZ
Pogo transposable element with ZNF domain

1

8

High-throughput

0.479

High

344963

SMC5
Structural maintenance of chromosomes protein 5

1

4

High-throughput

0.479

High

344970

SP7
Transcription factor Sp7

1

20

High-throughput

0.479

High

344971

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

344973

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

1

High-throughput

0.479

High

344975

ESR2
Estrogen receptor beta

1

12

High-throughput

0.479

High

344977

BIRC7
Baculoviral IAP repeat-containing protein 7

1

1

High-throughput

0.479

High

344978

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

2

High-throughput

0.479

High

344980

NSL1
Kinetochore-associated protein NSL1 homolog

1

1

High-throughput

0.479

High

344982

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

1

High-throughput

0.479

High

344984

CIC
Protein capicua homolog

1

4

High-throughput

0.479

High

344986

RING2
E3 ubiquitin-protein ligase RING2

1

7

High-throughput

0.479

High

344987

FEV
Protein FEV

1

7

High-throughput

0.479

High

344991

SOX7
Transcription factor SOX-7

1

10

High-throughput

0.479

High

344992

KLF16
Krueppel-like factor 16

1

20

High-throughput

0.479

High

344997

WWTR1
WW domain-containing transcription regulator protein 1

1

2

High-throughput

0.479

High

344998

MIS12
Protein MIS12 homolog

1

1

High-throughput

0.479

High

344999

DSN1
Kinetochore-associated protein DSN1 homolog

1

1

High-throughput

0.479

High

345005

SOX17
Transcription factor SOX-17

1

12

High-throughput

0.479

High

345011

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

345012

VSX1
Visual system homeobox 1

1

7

High-throughput

0.479

High

345015

NXF1
Nuclear RNA export factor 1

1

1

High-throughput

0.479

High

345018

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

1

1

Small-scale

0.479

High

345019

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

345020

FBW1B
F-box/WD repeat-containing protein 11

1

1

High-throughput

0.479

High

345021

ELF5
ETS-related transcription factor Elf-5

1

9

High-throughput

0.479

High

345025

ASF1A
Histone chaperone ASF1A

1

1

High-throughput

0.479

High

345026

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

20

Small-scale

0.479

High

345027

ZN330
Zinc finger protein 330

1

3

High-throughput

0.479

High

345029

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.479

High

345030

CDY2
Testis-specific chromodomain protein Y 2

1

5

High-throughput

0.479

High

254318

CC14B
Dual specificity protein phosphatase CDC14B

1

0

High-throughput

0.458

High

344899

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

344900

HMGA2
High mobility group protein HMGI-C

1

0

Small-scale

0.458

High

344913

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

344920

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

344922

TFAP4
Transcription factor AP-4

1

0

Small-scale

0.458

High

344947

RC3H1
Roquin-1

1

0

High-throughput

0.458

High

344950

IFIX
Pyrin and HIN domain-containing protein 1

1

0

High-throughput

0.458

High

344959

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

344962

BAP18
BPTF-associated chromatin complex component 1

1

0

High-throughput

0.458

High

344988

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

345000

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

0

High-throughput

0.458

High

345022

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

344885

EAA3
Excitatory amino acid transporter 3

1

4

High-throughput

0.445

High

344889

RS9
Small ribosomal subunit protein uS4

1

1

Small-scale

0.445

High

344974

S39A7
Zinc transporter SLC39A7

1

4

High-throughput

0.445

High

345010

S22AB
Solute carrier family 22 member 11

1

2

High-throughput

0.445

High

292990

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.437

High

344846

PRPC
Salivary acidic proline-rich phosphoprotein 1/2

1

1

High-throughput

0.437

High

344906

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

2

High-throughput

0.437

High

344948

OTUD1
OTU domain-containing protein 1

1

1

High-throughput

0.437

High

344961

CCD71
Coiled-coil domain-containing protein 71

1

1

Small-scale

0.437

High

345001

PKHA4
Pleckstrin homology domain-containing family A member 4

1

16

High-throughput

0.437

High

344915

RPP30
Ribonuclease P protein subunit p30

1

0

High-throughput

0.426

High

344921

E2F1
Transcription factor E2F1

1

0

High-throughput

0.426

High

344994

IFIH1
Interferon-induced helicase C domain-containing protein 1

1

0

Small-scale

0.426

High

344883

EAA1
Excitatory amino acid transporter 1

1

4

High-throughput

0.407

High

344884

EAA2
Excitatory amino acid transporter 2

1

4

High-throughput

0.407

High

344945

S39AC
Zinc transporter ZIP12

1

4

High-throughput

0.407

High

345013

DOK5
Docking protein 5

2

0

High-throughput

0.300

High

345006

CH033
UPF0488 protein C8orf33

1

0

High-throughput

0.265

Low

344854

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

344895

ARL4D
ADP-ribosylation factor-like protein 4D

1

0

High-throughput

0.249

Low

344955

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.249

Low

344967

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

345014

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low

344864

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.232

Low

344993

S17A9
Voltage-gated purine nucleotide uniporter SLC17A9

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025