Protein: I23O1
Indoleamine 2,3-dioxygenase 1 (IDO-1) (EC 1.13.11.52) (Indoleamine-pyrrole 2,3-dioxygenase)

Gene: I23O1, IDO1
Organism: Homo sapiens
Interactions: 11
UniProt ID: P14902

Gene Ontology (top 5):
GO:0002666 - positive regulation of T cell tolerance induction
GO:0002678 - positive regulation of chronic inflammatory response
GO:0002830 - positive regulation of type 2 immune response
GO:0004833 - tryptophan 2,3-dioxygenase activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

576924

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.529

High

576922

PP16A
Protein phosphatase 1 regulatory subunit 16A

1

0

High-throughput

0.518

High

144041

MA2B1
Lysosomal alpha-mannosidase

1

0

High-throughput

0.513

High

421432

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

576923

DDX24
ATP-dependent RNA helicase DDX24

1

0

High-throughput

0.473

High

576925

FXL17
F-box/LRR-repeat protein 17

1

0

Small-scale

0.460

High

378410

IFNG
Interferon gamma

1

0

Small-scale

0.458

High

576920

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

Small-scale

0.458

High

576921

EEA1
Early endosome antigen 1

1

0

High-throughput

0.458

High

576919

INGR1
Interferon gamma receptor 1

1

0

Small-scale

0.249

Low

516644

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025