HitPredict - High confidence protein-protein interactions

Protein: TNF11
Tumor necrosis factor ligand superfamily member 11 (Osteoclast differentiation factor) (ODF) (Osteoprotegerin ligand) (OPGL) (Receptor activator of nuclear factor kappa-B ligand) (RANKL) (TNF-related activation-induced cytokine) (TRANCE) (CD antigen CD254) [Cleaved into: Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form]

Gene: TNF11, Tnfsf11
Organism: Mus musculus
Interactions: 10
UniProt ID: O35235

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001503 - ossification
GO:0002158 - osteoclast proliferation
GO:0002548 - monocyte chemotaxis
GO:0005125 - cytokine activity

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
204499	TNR11 Tumor necrosis factor receptor superfamily member 11A	4	20	Small-scale	0.903	High
148115	TR11B Tumor necrosis factor receptor superfamily member 11B	1	20	Small-scale	0.730	High
204498	TNF11 Tumor necrosis factor ligand superfamily member 11	1	8	Small-scale	0.647	High
204500	EGR2 E3 SUMO-protein ligase EGR2	1	5	Small-scale	0.479	High
204501	TRAF6 TNF receptor-associated factor 6	1	9	Small-scale	0.479	High
204502	TNAP3 Tumor necrosis factor alpha-induced protein 3	1	3	Small-scale	0.479	High
204504	SHRPN Sharpin	1	3	Small-scale	0.479	High
204505	RNF31 E3 ubiquitin-protein ligase RNF31	1	3	Small-scale	0.479	High
204503	STAC2 SH3 and cysteine-rich domain-containing protein 2	1	13	Small-scale	0.437	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025