Protein: RNF31
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (Putative Ariadne-like ubiquitin ligase) (PAUL) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31)

Gene: RNF31
Organism: Mus musculus
Interactions: 18
UniProt ID: Q924T7

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0009898 - cytoplasmic side of plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

509228

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

2

20

Small-scale

0.778

High

1363382

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

6

19

Small-scale

0.730

High

312511

NEMO
NF-kappa-B essential modulator

4

16

Small-scale

0.705

High

1362262

SHRPN
Sharpin

4

4

Small-scale

0.703

High

957266

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

Small-scale

0.647

High

669430

TNR1A
Tumor necrosis factor receptor superfamily member 1A

3

7

Small-scale

0.640

High

449250

TNFA
Tumor necrosis factor

2

3

Small-scale

0.584

High

1281914

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

Small-scale

0.561

High

1190000

OTUL
Ubiquitin thioesterase otulin

1

2

Small-scale

0.512

High

204505

TNF11
Tumor necrosis factor ligand superfamily member 11

1

3

Small-scale

0.479

High

312163

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

9

Small-scale

0.479

High

1033494

TERA
Transitional endoplasmic reticulum ATPase

1

7

Small-scale

0.479

High

1188860

STING
Stimulator of interferon genes protein

1

2

High-throughput

0.479

High

1221353

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

12

Small-scale

0.479

High

811884

TRAF1
TNF receptor-associated factor 1

1

11

High-throughput

0.457

High

1222170

MUSK
Muscle, skeletal receptor tyrosine-protein kinase

1

3

Small-scale

0.437

High

1363381

Q99K94
Signal transducer and activator of transcription

1

7

Small-scale

0.437

High

1317415

ALMS1
Centrosome-associated protein ALMS1

1

7

Small-scale

0.417

High


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Last updated: 11Aug2025