Protein: SHRPN
Sharpin (Shank-associated RH domain-interacting protein) (Shank-interacting protein-like 1) (mSIPL1)

Gene: SHRPN, Sharpin
Organism: Mus musculus
Interactions: 27
UniProt ID: Q91WA6

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0007005 - mitochondrion organization
GO:0008270 - zinc ion binding
GO:0008544 - epidermis development
GO:0010803 - regulation of tumor necrosis factor-mediated signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1362262

RNF31
E3 ubiquitin-protein ligase RNF31

4

4

Small-scale

0.703

High

1362266

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

4

5

Small-scale

0.696

High

509210

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

2

4

Small-scale

0.602

High

811925

TRAF2
TNF receptor-associated factor 2

2

6

Small-scale

0.576

High

147614

EYA2
Protein phosphatase EYA2

1

4

Small-scale

0.552

High

1021852

EYA1
Protein phosphatase EYA1

1

3

Small-scale

0.535

High

548165

ITA5
Integrin alpha-5

1

7

Small-scale

0.501

High

312510

NEMO
NF-kappa-B essential modulator

1

3

Small-scale

0.500

High

204504

TNF11
Tumor necrosis factor ligand superfamily member 11

1

3

Small-scale

0.479

High

449249

TNFA
Tumor necrosis factor

1

3

Small-scale

0.479

High

669429

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

5

Small-scale

0.479

High

921297

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

Small-scale

0.479

High

1204078

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

3

Small-scale

0.479

High

1362265

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

1

Small-scale

0.479

High

98270

E9QAE4
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

0

Small-scale

0.458

High

205178

FYB1
FYN-binding protein 1

1

0

Small-scale

0.458

High

312333

ZN106
Zinc finger protein 106

1

0

Small-scale

0.458

High

1362263

STK24
Serine/threonine-protein kinase 24

1

0

Small-scale

0.458

High

1362267

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

Small-scale

0.458

High

921218

CUX1
Homeobox protein cut-like 1

1

3

Small-scale

0.437

High

999982

SURF6
Surfeit locus protein 6

1

1

Small-scale

0.437

High

1190971

CAN13
Calpain-13

1

1

Small-scale

0.437

High

266674

PACA
Pituitary adenylate cyclase-activating polypeptide

1

0

Small-scale

0.249

Low

1135289

TEKT4
Tektin-4

1

0

Small-scale

0.249

Low

1189653

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

0

Small-scale

0.249

Low

1274141

ASAP2
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2

1

0

Small-scale

0.249

Low

1362264

SCNBA
Sodium channel protein type 11 subunit alpha

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025