Interactor 1: IRS2 (P81122)
Insulin receptor substrate 2 (IRS-2) (4PS)
Gene: IRS2

Interactor 2: GRB10 (Q60760)
Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Maternally expressed gene 1 protein)
Gene: GRB10

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 12783867
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IRS~PH, PH~PH, PH~RA
Common GO terms GO:0005158 - insulin receptor binding
GO:0005829 - cytosol
GO:0008286 - insulin receptor signaling pathway
GO:0030674 - protein-macromolecule adaptor activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1321
Mm

1 621
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024