Protein: CP21A
Steroid 21-hydroxylase (EC 1.14.14.16) (21-OHase) (Cytochrome P-450c21) (Cytochrome P450 21) (Cytochrome P450 XXI) (Cytochrome P450-C21) (Cytochrome P450-C21B)

Gene: CP21A, CYP21A2
Organism: Homo sapiens
Interactions: 23
UniProt ID: P08686

Gene Ontology (top 5):
GO:0004509 - steroid 21-monooxygenase activity
GO:0005496 - steroid binding
GO:0005506 - iron ion binding
GO:0005789 - endoplasmic reticulum membrane
GO:0006694 - steroid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

475198

HEMH
Ferrochelatase, mitochondrial

1

1

High-throughput

0.445

High

466

NBPFJ
NBPF family member NBPF19

1

1

High-throughput

0.439

High

70090

CRTP1
Cysteine-rich tail protein 1

1

2

High-throughput

0.439

High

475200

HXA1
Homeobox protein Hox-A1

1

2

High-throughput

0.439

High

475201

CREB5
Cyclic AMP-responsive element-binding protein 5

1

3

High-throughput

0.439

High

475202

PO4F2
POU domain, class 4, transcription factor 2

1

1

High-throughput

0.439

High

475203

LCE3C
Late cornified envelope protein 3C

1

1

High-throughput

0.439

High

475205

LCE1F
Late cornified envelope protein 1F

1

1

High-throughput

0.439

High

475206

LCE3B
Late cornified envelope protein 3B

1

3

High-throughput

0.439

High

475207

LCE2C
Late cornified envelope protein 2C

1

1

High-throughput

0.439

High

475208

LCE5A
Late cornified envelope protein 5A

1

1

High-throughput

0.439

High

475209

NT2NA
Notch homolog 2 N-terminal-like protein A

1

1

High-throughput

0.439

High

475211

KRA13
Keratin-associated protein 1-3

1

6

High-throughput

0.439

High

475212

NR4A3
Nuclear receptor subfamily 4 group A member 3

1

4

High-throughput

0.439

High

475213

LCE3D
Late cornified envelope protein 3D

1

2

High-throughput

0.439

High

475214

KRA92
Keratin-associated protein 9-2

1

6

High-throughput

0.439

High

475215

KRA42
Keratin-associated protein 4-2

1

6

High-throughput

0.439

High

475216

PICK1
PRKCA-binding protein

1

1

High-throughput

0.439

High

475217

CRCT1
Cysteine-rich C-terminal protein 1

1

1

High-throughput

0.439

High

475197

CH60
60 kDa heat shock protein, mitochondrial

2

0

High-throughput

0.313

High

475199

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.269

Low

475204

LCE1D
Late cornified envelope protein 1D

1

0

High-throughput

0.251

Low

475210

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025