Protein: PO4F2
POU domain, class 4, transcription factor 2 (Brain-specific homeobox/POU domain protein 3B) (Brain-3B) (Brn-3B)

Gene: PO4F2, POU4F2
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q12837

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000165 - MAPK cascade
GO:0000785 - chromatin
GO:0000791 - euchromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

70964

NOTO
Homeobox protein notochord

2

20

High-throughput

0.783

High

249323

DLX3
Homeobox protein DLX-3

2

20

High-throughput

0.783

High

895709

LHX2
LIM/homeobox protein Lhx2

2

20

High-throughput

0.783

High

1086975

CRDL2
Chordin-like protein 2

2

5

High-throughput

0.606

High

1086978

IKBD
NF-kappa-B inhibitor delta

2

2

High-throughput

0.606

High

1086980

PCSK5
Proprotein convertase subtilisin/kexin type 5

2

3

High-throughput

0.606

High

1086981

RBPMS
RNA-binding protein with multiple splicing

2

1

High-throughput

0.606

High

1086984

HDHD3
Haloacid dehalogenase-like hydrolase domain-containing protein 3

2

4

High-throughput

0.606

High

1086993

SPY4
Protein sprouty homolog 4

2

2

High-throughput

0.606

High

376818

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

2

0

High-throughput

0.580

High

705323

GRN
Progranulin

2

0

High-throughput

0.580

High

877597

CCN3
CCN family member 3

2

0

High-throughput

0.580

High

1081358

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

1086963

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.580

High

1086995

MMAD
Cobalamin trafficking protein CblD

2

0

High-throughput

0.580

High

1086996

PLS2
Phospholipid scramblase 2

2

0

High-throughput

0.580

High

1086998

PP13
Galactoside-binding soluble lectin 13

2

0

High-throughput

0.580

High

300750

KRT38
Keratin, type I cuticular Ha8

2

9

High-throughput

0.553

High

665924

IBP6
Insulin-like growth factor-binding protein 6

2

1

High-throughput

0.553

High

685842

KRA59
Keratin-associated protein 5-9

2

20

High-throughput

0.553

High

890629

RGS19
Regulator of G-protein signaling 19

2

1

High-throughput

0.553

High

948266

KR121
Keratin-associated protein 12-1

2

2

High-throughput

0.553

High

948312

KR122
Keratin-associated protein 12-2

2

19

High-throughput

0.553

High

949535

KR123
Keratin-associated protein 12-3

2

2

High-throughput

0.553

High

950465

KR108
Keratin-associated protein 10-8

2

18

High-throughput

0.553

High

950754

KR109
Keratin-associated protein 10-9

2

20

High-throughput

0.553

High

1007471

KRT83
Keratin, type II cuticular Hb3

2

2

High-throughput

0.553

High

1009643

NGAL
Neutrophil gelatinase-associated lipocalin

2

1

High-throughput

0.553

High

1086952

K1H1
Keratin, type I cuticular Ha1

2

9

High-throughput

0.553

High

1086953

VWC2
Brorin

2

4

High-throughput

0.553

High

1086956

KRA61
Keratin-associated protein 6-1

2

1

High-throughput

0.553

High

1086959

KR133
Keratin-associated protein 13-3

2

2

High-throughput

0.553

High

1086962

GT253
Inactive glycosyltransferase 25 family member 3

2

1

High-throughput

0.553

High

1086968

KR511
Keratin-associated protein 5-11

2

18

High-throughput

0.553

High

1086970

KRA54
Keratin-associated protein 5-4

2

14

High-throughput

0.553

High

1086971

KRA53
Keratin-associated protein 5-3

2

17

High-throughput

0.553

High

1086974

ATL4
ADAMTS-like protein 4

2

2

High-throughput

0.553

High

1086977

TRI42
Tripartite motif-containing protein 42

2

13

High-throughput

0.553

High

1086979

KRT35
Keratin, type I cuticular Ha5

2

9

High-throughput

0.553

High

1086983

KR412
Keratin-associated protein 4-12

2

19

High-throughput

0.553

High

1086985

KRA98
Keratin-associated protein 9-8

2

19

High-throughput

0.553

High

1086986

KRA93
Keratin-associated protein 9-3

2

19

High-throughput

0.553

High

1086987

KRA92
Keratin-associated protein 9-2

2

19

High-throughput

0.553

High

1086988

KR411
Keratin-associated protein 4-11

2

19

High-throughput

0.553

High

1086989

KRA45
Keratin-associated protein 4-5

2

19

High-throughput

0.553

High

1086990

KRA44
Keratin-associated protein 4-4

2

19

High-throughput

0.553

High

1086991

KRA42
Keratin-associated protein 4-2

2

19

High-throughput

0.553

High

1086994

CHRD
Chordin

2

7

High-throughput

0.553

High

395999

ESR1
Estrogen receptor

1

20

Small-scale

0.527

High

1086982

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

2

High-throughput

0.489

High

950053

KR105
Keratin-associated protein 10-5

1

19

High-throughput

0.470

High

950927

KR10B
Keratin-associated protein 10-11

1

19

High-throughput

0.470

High

1065868

Q08AG9
Steroid 21-hydroxylase

1

1

High-throughput

0.470

High

1086957

KRA63
Keratin-associated protein 6-3

1

1

High-throughput

0.470

High

475202

CP21A
Steroid 21-hydroxylase

1

1

High-throughput

0.439

High

949691

KR101
Keratin-associated protein 10-1

1

20

High-throughput

0.439

High

1059627

KRA11
Keratin-associated protein 1-1

1

19

High-throughput

0.439

High

1086976

KR131
Keratin-associated protein 13-1

1

2

High-throughput

0.439

High

70187

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

426078

PPB1
Alkaline phosphatase, placental type

2

0

High-throughput

0.316

High

532138

RET3
Retinol-binding protein 3

2

0

High-throughput

0.316

High

584679

MCP
Membrane cofactor protein

2

0

High-throughput

0.316

High

694333

CO8A1
Collagen alpha-1(VIII) chain

2

0

High-throughput

0.316

High

949642

KR124
Keratin-associated protein 12-4

2

0

High-throughput

0.316

High

1086954

KR192
Keratin-associated protein 19-2

2

0

High-throughput

0.316

High

1086955

KR212
Keratin-associated protein 21-2

2

0

High-throughput

0.316

High

1086958

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.316

High

1086960

KR197
Keratin-associated protein 19-7

2

0

High-throughput

0.316

High

1086964

LCE1C
Late cornified envelope protein 1C

2

0

High-throughput

0.316

High

1086965

LCE1F
Late cornified envelope protein 1F

2

0

High-throughput

0.316

High

1086967

LCE5A
Late cornified envelope protein 5A

2

0

High-throughput

0.316

High

1086969

KRA56
Keratin-associated protein 5-6

2

0

High-throughput

0.316

High

1086972

IGFL1
Insulin growth factor-like family member 1

2

0

High-throughput

0.316

High

1086973

LYPD2
Ly6/PLAUR domain-containing protein 2

2

0

High-throughput

0.316

High

1086992

KRA32
Keratin-associated protein 3-2

2

0

High-throughput

0.316

High

1086997

F86C1
Putative protein FAM86C1P

2

0

High-throughput

0.316

High

1086999

CHIC2
Cysteine-rich hydrophobic domain-containing protein 2

2

0

High-throughput

0.316

High

1086961

HIG2B
HIG1 domain family member 2B

1

0

High-throughput

0.268

Low

1086966

LCE2C
Late cornified envelope protein 2C

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025