Protein: PACA
Pituitary adenylate cyclase-activating polypeptide (PACAP) [Cleaved into: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)]

Gene: PACA, ADCYAP1
Organism: Homo sapiens
Interactions: 34
UniProt ID: P18509

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005184 - neuropeptide hormone activity
GO:0005576 - extracellular region
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 - activation of adenylate cyclase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

577454

PACR
Pituitary adenylate cyclase-activating polypeptide type I receptor

1

2

Small-scale

0.692

High

577476

PCS1N
ProSAAS

3

0

High-throughput

0.638

High

577469

PXDN
Peroxidasin homolog

2

1

High-throughput

0.611

High

577461

STK4
Serine/threonine-protein kinase 4

3

1

High-throughput

0.609

High

577462

STK3
Serine/threonine-protein kinase 3

3

1

High-throughput

0.609

High

577455

SCTR
Secretin receptor

1

2

Small-scale

0.527

High

577464

ARMC8
Armadillo repeat-containing protein 8

1

0

High-throughput

0.513

High

577470

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.513

High

577453

DPP4
Dipeptidyl peptidase 4

1

3

Small-scale

0.501

High

394082

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.493

High

500716

CLUS
Clusterin

1

0

Small-scale

0.484

High

577458

YPEL5
Protein yippee-like 5

1

0

High-throughput

0.458

High

577460

SEPR
Prolyl endopeptidase FAP

1

3

Small-scale

0.457

High

577477

MKLN1
Muskelin

1

1

High-throughput

0.437

High

570619

DCAM
S-adenosylmethionine decarboxylase proenzyme

3

0

High-throughput

0.347

High

577456

ICLN
Methylosome subunit pICln

3

0

High-throughput

0.347

High

577459

NUCB1
Nucleobindin-1

3

0

High-throughput

0.347

High

577466

GCC2
GRIP and coiled-coil domain-containing protein 2

3

0

High-throughput

0.347

High

577472

SAV1
Protein salvador homolog 1

3

0

High-throughput

0.347

High

577478

T10B
Mitochondrial import inner membrane translocase subunit Tim10 B

3

0

High-throughput

0.347

High

320599

GGPPS
Geranylgeranyl pyrophosphate synthase

2

0

High-throughput

0.328

High

577463

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

2

0

High-throughput

0.328

High

171120

CETN3
Centrin-3

2

0

High-throughput

0.318

High

577471

CSN8
COP9 signalosome complex subunit 8

2

0

High-throughput

0.318

High

577474

COPRS
Coordinator of PRMT5 and differentiation stimulator

2

0

High-throughput

0.318

High

528510

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.282

High

520683

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

0

High-throughput

0.279

Low

577457

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

0

High-throughput

0.279

Low

255492

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

577465

GID4
Glucose-induced degradation protein 4 homolog

1

0

High-throughput

0.249

Low

577467

P20D2
Xaa-Arg dipeptidase

1

0

High-throughput

0.249

Low

577473

OSBL3
Oxysterol-binding protein-related protein 3

1

0

High-throughput

0.249

Low

577475

GID8
Glucose-induced degradation protein 8 homolog

1

0

High-throughput

0.249

Low

577468

CPMD8
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8

1

0

Small-scale

0.213

Low


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Last updated: 15 Jul 2024