Protein: FBX27
F-box only protein 27 (F-box/G-domain protein 5)

Gene: FBX27, FBXO27
Organism: Homo sapiens
Interactions: 19
UniProt ID: Q8NI29

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006516 - glycoprotein catabolic process
GO:0019005 - SCF ubiquitin ligase complex
GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

992269

SKP1
S-phase kinase-associated protein 1

4

7

Small-scale

0.890

High

1112610

CUL1
Cullin-1

2

8

Small-scale

0.776

High

533722

CLUS
Clusterin

2

1

High-throughput

0.628

High

1341057

NELL1
Protein kinase C-binding protein NELL1

2

20

High-throughput

0.628

High

983896

RBX1
E3 ubiquitin-protein ligase RBX1

2

5

Small-scale

0.601

High

1341059

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

Small-scale

0.501

High

160826

TOR1B
Torsin-1B

1

5

High-throughput

0.489

High

1295015

TMM25
Transmembrane protein 25

1

1

High-throughput

0.489

High

1341056

OIT3
Oncoprotein-induced transcript 3 protein

1

20

High-throughput

0.489

High

1341058

BOC
Brother of CDO

1

8

High-throughput

0.489

High

284404

CLN5
Bis(monoacylglycero)phosphate synthase CLN5

1

2

Small-scale

0.479

High

461731

HS90A
Heat shock protein HSP 90-alpha

1

5

High-throughput

0.479

High

468618

HS90B
Heat shock protein HSP 90-beta

1

5

High-throughput

0.479

High

540575

LAMP1
Lysosome-associated membrane glycoprotein 1

1

5

Small-scale

0.479

High

390685

TFR1
Transferrin receptor protein 1

1

3

Small-scale

0.437

High

562250

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

Small-scale

0.437

High

596884

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

1

Small-scale

0.437

High

549832

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

0

High-throughput

0.279

Low

604403

ASM
Sphingomyelin phosphodiesterase

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025