Protein: CLN5
Bis(monoacylglycero)phosphate synthase CLN5 (BMP synthase CLN5) (EC 2.3.1.-) (Ceroid-lipofuscinosis neuronal protein 5) (Protein CLN5) (Palmitoyl protein thioesterase CLN5) (EC 3.1.2.22) (S-depalmitoylase CLN5) [Cleaved into: Bis(monoacylglycero)phosphate synthase CLN5, secreted form]

Gene: CLN5
Organism: Homo sapiens
Interactions: 68
UniProt ID: O75503

Gene Ontology (top 5):
GO:0005537 - D-mannose binding
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005775 - vacuolar lumen
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

284419

FBX6
F-box only protein 6

3

2

Small-scale

0.656

High

284386

FDFT
Squalene synthase

2

0

High-throughput

0.580

High

284402

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

2

0

High-throughput

0.580

High

284409

CALR3
Calreticulin-3

2

3

High-throughput

0.558

High

284368

IGF2
Insulin-like growth factor 2

2

1

High-throughput

0.553

High

284401

S41A1
Solute carrier family 41 member 1

2

1

High-throughput

0.553

High

284408

S41A2
Solute carrier family 41 member 2

2

1

High-throughput

0.553

High

284376

MPRI
Cation-independent mannose-6-phosphate receptor

1

1

High-throughput

0.536

High

284424

FBX2
F-box only protein 2

1

2

High-throughput

0.536

High

284366

AGRL1
Adhesion G protein-coupled receptor L1

1

0

High-throughput

0.513

High

284380

PRG2
Bone marrow proteoglycan

1

0

High-throughput

0.513

High

284385

GALNS
N-acetylgalactosamine-6-sulfatase

1

0

High-throughput

0.513

High

284388

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.513

High

284413

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

0

High-throughput

0.513

High

284416

ZWILC
Protein zwilch homolog

1

0

High-throughput

0.513

High

284418

XPP3
Xaa-Pro aminopeptidase 3

1

0

High-throughput

0.513

High

284373

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.493

High

284394

CLN3
Battenin

1

0

Small-scale

0.493

High

185293

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

170583

CLGN
Calmegin

1

3

Small-scale

0.479

High

229602

CALU
Calumenin

1

1

Small-scale

0.479

High

284372

ADT2
ADP/ATP translocase 2

1

3

Small-scale

0.479

High

284377

ADT1
ADP/ATP translocase 1

1

3

Small-scale

0.479

High

284378

ADT3
ADP/ATP translocase 3

1

3

Small-scale

0.479

High

284379

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

Small-scale

0.479

High

284381

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

1

Small-scale

0.479

High

284383

CALR
Calreticulin

1

3

Small-scale

0.479

High

284384

CALX
Calnexin

1

3

Small-scale

0.479

High

284387

TXTP
Tricarboxylate transport protein, mitochondrial

1

5

Small-scale

0.479

High

284395

OS9
Protein OS-9

1

1

Small-scale

0.479

High

284396

RCN2
Reticulocalbin-2

1

1

Small-scale

0.479

High

284404

FBX27
F-box only protein 27

1

2

Small-scale

0.479

High

284399

TMM31
Transmembrane protein 31

1

0

High-throughput

0.460

High

162137

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

Small-scale

0.458

High

172331

XPO1
Exportin-1

1

0

Small-scale

0.458

High

209401

SERA
D-3-phosphoglycerate dehydrogenase

1

0

Small-scale

0.458

High

284367

CDS2
Phosphatidate cytidylyltransferase 2

1

0

Small-scale

0.458

High

284371

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

Small-scale

0.458

High

284374

MMP3
Stromelysin-1

1

0

High-throughput

0.458

High

284375

DOPO
Dopamine beta-hydroxylase

1

0

Small-scale

0.458

High

284382

ARF4
ADP-ribosylation factor 4

1

0

Small-scale

0.458

High

284389

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

0

Small-scale

0.458

High

284390

HMCS1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic

1

0

Small-scale

0.458

High

284391

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.458

High

284397

GANAB
Neutral alpha-glucosidase AB

1

0

Small-scale

0.458

High

284398

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

0

High-throughput

0.458

High

284411

KCTD7
BTB/POZ domain-containing protein KCTD7

1

0

Small-scale

0.458

High

284415

SPNS1
Protein spinster homolog 1

1

0

Small-scale

0.458

High

284420

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

0

Small-scale

0.458

High

284422

SE1L1
Protein sel-1 homolog 1

1

0

Small-scale

0.458

High

217299

PROM1
Prominin-1

1

0

Small-scale

0.438

High

284392

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

5

Small-scale

0.437

High

284407

ERLEC
Endoplasmic reticulum lectin 1

1

1

High-throughput

0.437

High

284417

GHC1
Mitochondrial glutamate carrier 1

1

5

Small-scale

0.437

High

284423

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

4

Small-scale

0.437

High

284406

LIPH
Lipase member H

2

0

High-throughput

0.318

High

284421

OBP2A
Odorant-binding protein 2a

2

0

High-throughput

0.318

High

284405

GP152
Probable G-protein coupled receptor 152

2

0

High-throughput

0.316

High

284365

CLC3A
C-type lectin domain family 3 member A

1

0

High-throughput

0.279

Low

284370

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

0

High-throughput

0.279

Low

284403

CNPY4
Protein canopy homolog 4

1

0

High-throughput

0.279

Low

284410

TAFA4
Chemokine-like protein TAFA-4

1

0

High-throughput

0.279

Low

284412

SPXN
Spexin

1

0

High-throughput

0.279

Low

107449

INSR2
Insulin, isoform 2

1

0

High-throughput

0.251

Low

284369

CP1A1
Cytochrome P450 1A1

1

0

High-throughput

0.249

Low

284393

TADBP
TAR DNA-binding protein 43

1

0

Small-scale

0.249

Low

284400

RHG36
Rho GTPase-activating protein 36

1

0

Small-scale

0.249

Low

284414

SFXN3
Sideroflexin-3

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025