Protein: DPOLQ
DNA polymerase theta (DNA polymerase eta) [Includes: Helicase POLQ (EC 3.6.4.12); DNA polymerase POLQ (EC 2.7.7.7) (RNA-directed DNA polymerase POLQ) (EC 2.7.7.49)]

Gene: DPOLQ, POLQ
Organism: Homo sapiens
Interactions: 19
UniProt ID: O75417

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003684 - damaged DNA binding
GO:0003678 - DNA helicase activity
GO:0003682 - chromatin binding
GO:0003887 - DNA-directed DNA polymerase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

281140

DPOLQ
DNA polymerase theta

1

11

Small-scale

0.740

High

281147

RBM25
RNA-binding protein 25

2

5

High-throughput

0.621

High

281150

RAD51
DNA repair protein RAD51 homolog 1

1

6

Small-scale

0.561

High

163673

TCRG1
Transcription elongation regulator 1

1

8

High-throughput

0.536

High

280432

PR40A
Pre-mRNA-processing factor 40 homolog A

1

14

High-throughput

0.536

High

281145

HSP74
Heat shock 70 kDa protein 4

1

7

High-throughput

0.536

High

281146

MAGA9
Melanoma-associated antigen 9

1

3

High-throughput

0.536

High

281151

TEBP
Prostaglandin E synthase 3

1

3

High-throughput

0.536

High

281154

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

5

High-throughput

0.536

High

271766

OBSL1
Obscurin-like protein 1

1

3

High-throughput

0.479

High

281141

HEXI1
Protein HEXIM1

1

2

High-throughput

0.479

High

281142

HMGB1
High mobility group protein B1

1

11

High-throughput

0.479

High

281144

NUCL
Nucleolin

1

11

High-throughput

0.479

High

281149

AP2S1
AP-2 complex subunit sigma

1

1

High-throughput

0.479

High

281152

SLN11
Schlafen family member 11

1

2

High-throughput

0.479

High

281153

SLX4
Structure-specific endonuclease subunit SLX4

1

4

High-throughput

0.479

High

281143

XRCC1
DNA repair protein XRCC1

1

0

Small-scale

0.458

High

281148

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.458

High


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Last updated: 11Aug2025