Protein: SCLY
Selenocysteine lyase (hSCL) (EC 4.4.1.16)

Gene: SCLY
Organism: Homo sapiens
Interactions: 16
UniProt ID: Q96I15

Gene Ontology (top 5):
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0006520 - amino acid metabolic process
GO:0009000 - selenocysteine lyase activity
GO:0016261 - selenocysteine catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1325752

LNX2
Ligand of Numb protein X 2

3

1

High-throughput

0.601

High

667983

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.513

High

849394

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.513

High

946446

MTPN
Myotrophin

1

0

High-throughput

0.513

High

1332097

EIF1A
Probable RNA-binding protein EIF1AD

1

0

High-throughput

0.513

High

1367779

TFG
Protein TFG

1

0

High-throughput

0.513

High

1393922

EXOS5
Exosome complex component RRP46

1

0

High-throughput

0.513

High

185933

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

355096

APBA3
Amyloid-beta A4 precursor protein-binding family A member 3

1

1

High-throughput

0.489

High

230399

CREB3
Cyclic AMP-responsive element-binding protein 3

1

0

High-throughput

0.486

High

1393921

SPS2
Selenide, water dikinase 2

1

0

Small-scale

0.480

High

242586

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

1255070

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1227255

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

1393923

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.299

High

1393924

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025